(Q41457961)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

review article

1 reference

title

Therapeutic strategies for Huntington's disease based on a molecular understanding of the disorder (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

N S Haque

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

P Borghesani

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

1 April 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

Trends in Molecular Medicine

2 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

175-183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

Neurobiology of Huntington's disease

2 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Homozygotes for Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Characterization and localization of the Huntington disease gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Huntington's disease gene (IT15) is widely expressed in human and rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Mouse Huntington's disease gene homolog (Hdh).

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

The identification of a functional nuclear localization signal in the Huntington disease protein

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Mitochondrial impairment reduces the threshold for in vivo NMDA-mediated neuronal death in the striatum.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Mitochondrial defect in Huntington's disease caudate nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Evidence that glyceraldehyde-3-phosphate dehydrogenase is involved in age-induced apoptosis in mature cerebellar neurons in culture.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Inactivation of the mouse Huntington's disease gene homolog Hdh

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Therapeutic antisense and ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Antisense gene therapy for neurodegenerative disease?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

A huntingtin-associated protein enriched in brain with implications for pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Trial of d-alpha-tocopherol in Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Transplanted xenogeneic neural cells in neurodegenerative disease models exhibit remarkable axonal target specificity and distinct growth patterns of glial and axonal fibres.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Huntington's disease: animal models and transplantation repair

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Human gene therapy--an immature genie, but certainly out of the bottle

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Effect of exogenous nerve growth factor on neurotoxicity of and neuronal gene delivery by a herpes simplex amplicon vector in the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Direct gene transfer into mouse muscle in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Persistence of plasmid DNA and expression in rat brain cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

IT15 gene expression in fetal human brain

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

HEAT repeats in the Huntington's disease protein

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901012-5

7 January 2021

10.1016/S1357-4310(97)01012-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9134531%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference