(Q41461417)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Heteronemin, a Spongean Sesterterpene, Induces Cell Apoptosis and Autophagy in Human Renal Carcinoma Cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Szu-Ying Wu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Ping-Jyun Sung

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Ya-Ling Chang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Shiow-Lin Pan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

18 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

BioMed Research International

17 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

738241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

17 February 2020

copyright license

start time

1 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Blocking autophagy enhances the apoptosis effect of bufalin on human hepatocellular carcinoma cells through endoplasmic reticulum stress and JNK activation

11 June 2018

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Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response

11 June 2018

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MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1.

11 June 2018

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Oxidative stress and autophagy: mediators of synapse growth?

11 June 2018

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Bortezomib induces autophagy in head and neck squamous cell carcinoma cells via JNK activation

11 June 2018

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c-Jun NH2-terminal kinase activation is essential for up-regulation of LC3 during ceramide-induced autophagy in human nasopharyngeal carcinoma cells

11 June 2018

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11 June 2018

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Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cells.

11 June 2018

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Looking beyond inhibition of VEGF/mTOR: emerging targets for renal cell carcinoma drug development

11 June 2018

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Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

11 June 2018

1 reference

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Mechanisms and functions of p38 MAPK signalling.

11 June 2018

1 reference

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Selective autophagy in cancer development and therapy

11 June 2018

1 reference

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Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy

11 June 2018

1 reference

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Signal integration by JNK and p38 MAPK pathways in cancer development

11 June 2018

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The applicability of mTOR inhibition in solid tumors.

11 June 2018

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Targeting mTOR in renal cell carcinoma

11 June 2018

1 reference

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mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.

11 June 2018

1 reference

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Cellular signaling perturbation by natural products

11 June 2018

1 reference

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Control of mitochondrial apoptosis by the Bcl-2 family

11 June 2018

1 reference

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YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway

11 June 2018

1 reference

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Autophagy in the Pathogenesis of Disease

11 June 2018

1 reference

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

11 June 2018

1 reference

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MAP kinase signalling pathways in cancer

11 June 2018

1 reference

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Reactive oxygen species-induced activation of the MAP kinase signaling pathways

11 June 2018

1 reference

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ERK MAP kinase in G cell cycle progression and cancer

11 June 2018

1 reference

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Ras, PI(3)K and mTOR signalling controls tumour cell growth

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Autophagy and antigen presentation

11 June 2018

1 reference

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Mechanisms of cytochrome c release from mitochondria

11 June 2018

1 reference

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Exploiting the PI3K/AKT pathway for cancer drug discovery

11 June 2018

1 reference

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Autophagy in cell death: an innocent convict?

11 June 2018

1 reference

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PI3K/Akt/mTOR pathway as a target for cancer therapy

11 June 2018

1 reference

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Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma.

11 June 2018

1 reference

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Autophagy: dual roles in life and death?

11 June 2018

1 reference

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Marine sponges as pharmacy

11 June 2018

1 reference

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Cytochrome C-mediated apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Development by self-digestion: molecular mechanisms and biological functions of autophagy

11 June 2018

1 reference

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Cellular autophagy: surrender, avoidance and subversion by microorganisms

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Cell death: critical control points

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Mitochondria: releasing power for life and unleashing the machineries of death

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Autophagosome formation in mammalian cells

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Caspase-independent cell deaths

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Chemistry and clinical biology of the bryostatins

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

AD-1, a novel ginsenoside derivative, shows anti-lung cancer activity via activation of p38 MAPK pathway and generation of reactive oxygen species.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Scalarane sesterterpenoids: semisynthesis and biological activity.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Life and death partners: apoptosis, autophagy and the cross-talk between them

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Antitubercular sesterterpenes from the Thai sponge Brachiaster sp.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4450260

Effects in vitro of pachymatismin, a glycoprotein from the marine sponge Pachymatisma johnstonii, on a non-small-cell bronchopulmonary carcinoma line (NSCLC-N6)

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26090440

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heteronemin, a spongean sesterterpene, inhibits TNF alpha-induced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26090440

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2015/738241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26090440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090440%20AND%20SRC:MED&resulttype=core&format=json