(Q41469628)

1 October 2017

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity (English)

1 reference

1 October 2017

Yasmina Noubia Abdiche

1

1 reference

1 October 2017

Yik Andy Yeung

2

1 reference

1 October 2017

Javier Chaparro-Riggers

3

1 reference

1 October 2017

Ishita Barman

4

1 reference

1 October 2017

Pavel Strop

5

1 reference

1 October 2017

Sherman Michael Chin

6

1 reference

1 October 2017

Amber Pham

7

1 reference

1 October 2017

Gary Bolton

8

1 reference

1 October 2017

Dan McDonough

9

1 reference

1 October 2017

Kevin Lindquist

10

1 reference

1 October 2017

Jaume Pons

11

1 reference

1 October 2017

Arvind Rajpal

12

1 reference

1 October 2017

1 January 2015

1 reference

1 October 2017

Monoclonal Antibodies

1 reference

1 October 2017

7

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1 October 2017

2

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1 October 2017

331-343

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Characterization and screening of IgG binding to the neonatal Fc receptor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Determining the binding affinity of therapeutic monoclonal antibodies towards their native unpurified antigens in human serum

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Expanding the ProteOn XPR36 biosensor into a 36-ligand array expedites protein interaction analysis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

FcRn: the neonatal Fc receptor comes of age.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Analysis of a family of antibodies with different half-lives in mice fails to find a correlation between affinity for FcRn and serum half-life

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,)

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Sedimentation equilibrium analysis of recombinant mouse FcRn with murine IgG1.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Characterization of the 2:1 complex between the class I MHC-related Fc receptor and its Fc ligand in solution

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Recombinant human IgG molecules lacking Fcgamma receptor I binding and monocyte triggering activities

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Stoichiometry of the interaction between the major histocompatibility complex-related Fc receptor and its Fc ligand

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Crystal structure of the complex of rat neonatal Fc receptor with Fc

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Effects of receptor dimerization on the interaction between the class I major histocompatibility complex-related Fc receptor and IgG.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Expression and crystallization of a soluble and functional form of an Fc receptor related to class I histocompatibility molecules

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Biacore surface matrix effects on the binding kinetics and affinity of an antigen/antibody complex.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Robust recombinant FcRn production in mammalian cells enabling oriented immobilization for IgG binding studies.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Reduced elimination of IgG antibodies by engineering the variable region.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Importance of neonatal FcR in regulating the serum half-life of therapeutic proteins containing the Fc domain of human IgG1: a comparative study of the affinity of monoclonal antibodies and Fc-fusion proteins to human neonatal FcR.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Humanized IgG1 variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Quantitative methods for developing Fc mutants with extended half-lives.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622529

Improving biosensor analysis

19 August 2018

1 reference

12 December 2020

Transepithelial transport of maternal antibody: purification of IgG receptor from newborn rat intestine

1 reference

12 December 2020

Binding of subclasses of rat immunoglobulin G to detergent-isolated Fc receptor from neonatal rat intestine

1 reference

12 December 2020

Crystallization and stoichiometry of binding of a complex between a rat intestinal Fc receptor and Fc

1 reference

12 December 2020

Exploring "one-shot" kinetics and small molecule analysis using the ProteOn XPR36 array biosensor

1 reference

12 December 2020

Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates

1 reference

12 December 2020

Human FcRn transgenic mice for pharmacokinetic evaluation of therapeutic antibodies

1 reference

12 December 2020

Pharmacokinetics of humanized monoclonal anti-tumor necrosis factor-{alpha} antibody and its neonatal Fc receptor variants in mice and cynomolgus monkeys

1 reference

12 December 2020

FcRn mediates elongated serum half-life of human IgG in cattle

1 reference

12 December 2020

Monoclonal antibodies with identical Fc sequences can bind to FcRn differentially with pharmacokinetic consequences

1 reference

12 December 2020

10.1080/19420862.2015.1008353

Identifiers

DOI

1 reference

1 October 2017

1 reference

1 October 2017

PubMed publication ID

25658443

1 reference