(Q36080399)

English

Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

8

object named as

Inger Sandlie

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jan Terje Andersen

1

object named as

Jan Terje Andersen

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

2

object named as

Stian Foss

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Vania E Kenanova

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Tove Olafsen

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Ingvild S Leikfoss

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Derry C Roopenian

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Anna M Wu

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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publication date

8 May 2012

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Europe PubMed Central

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12 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

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12 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

27

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

22927-22937

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

1 reference

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2 October 2017

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Enhanced antibody half-life improves in vivo activity

1 reference

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2 October 2017

ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies).

1 reference

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2 October 2017

Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Dependence of antibody-mediated presentation of antigen on FcRn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Podocytes use FcRn to clear IgG from the glomerular basement membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Fcgamma receptors as regulators of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Elucidation of intracellular recycling pathways leading to exocytosis of the Fc receptor, FcRn, by using multifocal plane microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Radioiodinated versus radiometal-labeled anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments: optimal pharmacokinetics for therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Tailoring antibodies for radionuclide delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Arming antibodies: prospects and challenges for immunoconjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Engineered antibody fragments and the rise of single domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Antibody-targeted radiation cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Engineered human IgG antibodies with longer serum half-lives in primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Increasing the serum persistence of an IgG fragment by random mutagenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

A major histocompatibility complex class I-related Fc receptor for IgG on rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Metabolic properties of IgG subclasses in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Biological activities of immunoglobulins of different classes and subclasses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Catabolism of human gammaG-immunoglobulins of different heavy chain subclasses. I. Catabolism of gammaG-myeloma proteins in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

2 October 2017

Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391105

11 July 2018

Quantitative methods for developing Fc mutants with extended half-lives.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

An engineered human IgG1 antibody with longer serum half-life.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Antibodies in the breakdown lane.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Pilot trial evaluating an 123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Sensitivity and specificity of Gold types 1 to 5 anti-carcinoembryonic antigen monoclonal antibodies: immunohistologic characterization in colorectal cancer and normal tissues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Clinical chemistry of human FcRn transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.355131

21 January 2018

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 stimulates gluconeogenesis in primary cultures of rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delineation of the amino acid residues involved in transcytosis and catabolism of mouse IgG1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the control of gene expression of the carcinoembryonic antigen family in human tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22570488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.355131

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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