(Q41491090)

English

Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells

scientific article published on July 2006

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells (English)

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

author name string

Chrystelle V Garat

1

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Dana Fankell

2

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Paul F Erickson

3

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Jane E-B Reusch

4

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Natalie N Bauer

5

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Ivan F McMurtry

6

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Dwight J Klemm

7

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

language of work or name

0 references

publication date

1 July 2006

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

26

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

13

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

4934-4948

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Reversal of experimental pulmonary hypertension by PDGF inhibition

1 reference

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11 June 2018

Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma

1 reference

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Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis

1 reference

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Differential TNF-signaling in chronic inflammatory disorders

1 reference

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11 June 2018

Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation

1 reference

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11 June 2018

The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypert

1 reference

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11 June 2018

Involvement of neuron-derived orphan receptor-1 (NOR-1) in LDL-induced mitogenic stimulus in vascular smooth muscle cells: role of CREB.

1 reference

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11 June 2018

Platelet-derived growth factor-BB-mediated activation of Akt suppresses smooth muscle-specific gene expression through inhibition of mitogen-activated protein kinase and redistribution of serum response factor

1 reference

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11 June 2018

Identification of p53 sequence elements that are required for MDM2-mediated nuclear export

1 reference

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11 June 2018

C-terminal ubiquitination of p53 contributes to nuclear export

1 reference

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11 June 2018

cAMP response element-binding protein mediates thrombin-induced proliferation of vascular smooth muscle cells

1 reference

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11 June 2018

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

1 reference

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11 June 2018

Membrane depolarization mediates phosphorylation and nuclear translocation of CREB in vascular smooth muscle cells.

1 reference

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11 June 2018

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway

1 reference

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11 June 2018

Molecular pathways of cyclic nucleotide-induced inhibition of arterial smooth muscle cell proliferation

1 reference

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11 June 2018

Phosphorylation-dependent targeting of cAMP response element binding protein to the ubiquitin/proteasome pathway in hypoxia

1 reference

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11 June 2018

The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.

1 reference

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11 June 2018

Inhibition of platelet-derived growth factor-induced mitogenesis by phosphodiesterase 3 inhibitors: role of protein kinase A in vascular smooth muscle cell mitogenesis

1 reference

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11 June 2018

A role for the serotonin transporter in hypoxia-induced pulmonary hypertension

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11 June 2018

Molecular mechanisms in intimal hyperplasia

1 reference

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11 June 2018

Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21

1 reference

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11 June 2018

Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489168

11 June 2018

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489168

11 June 2018

Endothelial cell responses to hypoxic stress

1 reference

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11 June 2018

CREB is a regulatory target for the protein kinase Akt/PKB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489168

11 June 2018

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489168

11 June 2018

Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation

1 reference

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11 June 2018

Phosphorylation of the cAMP response element binding protein CREB by cAMP-dependent protein kinase A and glycogen synthase kinase-3 alters DNA-binding affinity, conformation, and increases net charge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489168

11 June 2018

Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype

1 reference

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11 June 2018

Cellular and molecular mechanisms of pulmonary vascular remodeling

1 reference

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11 June 2018

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

1 reference

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11 June 2018

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

1 reference

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11 June 2018

Gating by cyclic AMP: expanded role for an old signaling pathway

1 reference

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11 June 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

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11 June 2018

Vascular remodeling in primary pulmonary hypertension. Potential role for transforming growth factor-beta

1 reference

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Characterization of fibroblast mitogens and chemoattractants produced by endothelial cells exposed to hypoxia

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11 June 2018

Immediate-early gene expression in response to hypertrophic and proliferative stimuli in pulmonary arterial smooth muscle cells.

1 reference

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11 June 2018

Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity

1 reference

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11 June 2018

Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells

1 reference

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11 June 2018

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB.

1 reference

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11 June 2018

Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat

1 reference

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Insulin-like Growth Factor I and Pulmonary Hypertension Induced by Continuous Air Embolization in Sheep

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11 June 2018

cAMP-response element-binding protein mediates prostaglandin F2alpha-induced hypertrophy of vascular smooth muscle cells

1 reference

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Imatinib for the treatment of pulmonary arterial hypertension

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Role of c-Jun N-terminal kinase in the PDGF-induced proliferation and migration of human adipose tissue-derived mesenchymal stem cells.

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19 August 2018

Sustained Akt/PKB activation and transient attenuation of c-jun N-terminal kinase in the inhibition of apoptosis by IGF-1 in vascular smooth muscle cells

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cAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular smooth muscle cell migration

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19 August 2018

ATP-induced mitogenesis is mediated by cyclic AMP response element-binding protein-enhanced TRPC4 expression and activity in human pulmonary artery smooth muscle cells

1 reference

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19 August 2018

PDGF stimulates DNA synthesis in human vascular smooth muscle cells via a novel wortmannin-insensitive phosphatidylinositol 3-kinase

1 reference

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1 reference

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19 August 2018

Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells

1 reference

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19 August 2018

Critical role of cAMP-response element-binding protein for angiotensin II-induced hypertrophy of vascular smooth muscle cells

1 reference

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19 August 2018

Increased expression and activity of RhoA are associated with increased DNA synthesis and reduced p27(Kip1) expression in the vasculature of hypertensive rats

1 reference

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Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs

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19 August 2018

Cyclic AMP regulates cytokine stimulation of endothelin-1 release in human vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular neuronal NO synthase is selectively upregulated by platelet-derived growth factor: involvement of the MEK/ERK pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G1 phase arrest of human smooth muscle cells by heparin, IL-4 and cAMP is linked to repression of cyclin D1 and cdk2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of phosphatidylinositol 3-kinase/Akt pathway in angiotensin II and insulin-like growth factor-1 modulation of nitric oxide synthase in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forskolin inhibits cyclin D1 expression in cultured airway smooth-muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of the cyclin D1 gene is mediated by multiple cis-elements, including SP1 sites and a cAMP-responsive element in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ANG II-induced neointimal growth is mediated via cPLA2- and PLD2-activated Akt in balloon-injured rat carotid artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin, growth factors, and cAMP: antagonism in the signal transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trapidil inhibits platelet-derived growth factor-stimulated mitogen-activated protein kinase cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of CREB by CaM-kinase IV activated by CaM-kinase IV kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16782881

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.02477-05

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

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