(Q41498958)

1 October 2017

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title

Autophagic proteolysis: control and specificity (English)

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1 October 2017

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Blommaart EF

1

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PubMed ID

9184851

1 October 2017

Luiken JJ

series ordinal

2

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PubMed ID

9184851

1 October 2017

Meijer AJ

series ordinal

3

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1 October 2017

1 May 1997

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Journal of Molecular Histology

1 October 2017

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1 October 2017

29

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1 October 2017

365-385

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1 October 2017

5

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Attachment of ribosomes to endoplasmic membranes in mouse pancreas. Degranulation in vivo caused by the inducers of autophagocytosis neutral red, vinblastine, puromycin, and cadmium ions, and prevention by cycloheximide

1 October 2017

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12 December 2020

Stress-induced alterations in autophagic pathway: relationship to ubiquitin system

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12 December 2020

Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity

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12 December 2020

Ubiquitin-activating enzyme, E1, is associated with maturation of autophagic vacuoles

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12 December 2020

The ubiquitin system for protein degradation

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12 December 2020

Autophagic vacuoles rapidly fuse with pre-existing lysosomes in cultured hepatocytes

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12 December 2020

Liver cell volume and protein synthesis

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12 December 2020

Mechanism of activation of liver glycogen synthase by swelling

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12 December 2020

Cytoskeletal changes in hepatocytes induced by Microcystis toxins and their relation to hyperphosphorylation of cell proteins.

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12 December 2020

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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12 December 2020

Control of hepatic proteolysis by leucine and isovaleryl-L-carnitine through a common locus. Evidence for a possible mechanism of recognition at the plasma membrane

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12 December 2020

Radial movement of lysosomes along microtubules in permeabilized macrophages

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12 December 2020

Autophagy and related mechanisms of lysosome-mediated protein degradation

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12 December 2020

Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles

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12 December 2020

Turnover of peroxisomal vesicles by autophagic proteolysis in cultured fibroblasts from Zellweger patients

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12 December 2020

Phosphoinositide 3-kinases and membrane traffic.

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12 December 2020

Serine/threonine kinases in the propagation of the early mitogenic response

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12 December 2020

Effect of phorbol esters on protein kinase C-zeta

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12 December 2020

Tissue and cellular distribution of the extended family of protein kinase C isoenzymes

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12 December 2020

Prelysosomal and lysosomal connections between autophagy and endocytosis

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12 December 2020

Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein

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12 December 2020

Autophagic degradation of peroxisomes in isolated rat hepatocytes.

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12 December 2020

Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6.

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12 December 2020

Ubiquitin in health and disease.

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12 December 2020

Cell volume in the regulation of hepatic function: a mechanism for metabolic control

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12 December 2020

Swelling of rat hepatocytes activates acetyl-CoA carboxylase in parallel to glycogen synthase

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12 December 2020

Phosphorylation of keratin intermediate filaments by protein kinase C, by calmodulin-dependent protein kinase and by cAMP-dependent protein kinase

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12 December 2020

Isolation and some properties of a 34-kDa-membrane protein that may be responsible for ribosome binding in rat liver rough microsomes

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12 December 2020

Autophagy and other vacuolar protein degradation mechanisms

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12 December 2020

Energy depletion and autophagy. Cytochemical and biochemical studies in isolated rat hepatocytes

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12 December 2020

Hepatocyte swelling increases inositol 1,4,5-trisphosphate, calcium and cyclic AMP concentration but antagonizes phosphorylase activation by Ca2+-dependent hormones

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12 December 2020

The ubiquitin-activating enzyme, E1, is required for stress-induced lysosomal degradation of cellular proteins.

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12 December 2020

Regulated import and degradation of a cytosolic protein in the yeast vacuole

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12 December 2020

Inhibition of autophagic-lysosomal delivery and autophagic lactolysis by asparagine

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12 December 2020

Amino acids regulate kidney cell protein breakdown

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12 December 2020

Amino acid control of proteolysis in perfused livers of synchronously fed rats. Mechanism and specificity of alanine co-regulation

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12 December 2020

Proteins containing peptide sequences related to Lys-Phe-Glu-Arg-Gln are selectively depleted in liver and heart, but not skeletal muscle, of fasted rats

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12 December 2020

Control of hepatic proteolysis by amino acids. The role of cell volume

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12 December 2020

Inhibition of hepatic proteolysis by insulin. Role of hormone-induced alterations of the cellular K+ balance

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12 December 2020

Ubiquitinated protein conjugates are specifically enriched in the lysosomal system of fibroblasts

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12 December 2020

Studies on the mechanisms of autophagy: maturation of the autophagic vacuole

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12 December 2020

In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome

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12 December 2020

Nitrogen metabolism and ornithine cycle function

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12 December 2020

Peptide sequences that target cytosolic proteins for lysosomal proteolysis

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12 December 2020

Absence of cytochrome P-450 and presence of autolysosomal membrane antigens on the isolation membranes and autophagosomal membranes in rat hepatocytes

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12 December 2020

Cell swelling inhibits proteolysis in perfused rat liver

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12 December 2020

Swelling of rat hepatocytes stimulates glycogen synthesis

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12 December 2020

Characterization of the isolation membranes and the limiting membranes of autophagosomes in rat hepatocytes by lectin cytochemistry

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12 December 2020

Studies on the mechanisms of autophagy: formation of the autophagic vacuole

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12 December 2020

Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes

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12 December 2020

Amino acid and hormonal control of macromolecular turnover in perfused rat liver. Evidence for selective autophagy

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12 December 2020

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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12 December 2020

Membrane mechanisms in volume and pH regulation in vertebrate cells

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12 December 2020

Ubiquitin-protein conjugates accumulate in the lysosomal system of fibroblasts treated with cysteine proteinase inhibitors

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12 December 2020

Effect of parenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery

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12 December 2020

A combination of intracellular leucine with either glutamate or aspartate inhibits autophagic proteolysis in isolated rat hepatocytes

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12 December 2020

Mechanism and regulation of protein degradation in liver

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12 December 2020

Lysosomal movements during heterophagy and autophagy: with special reference to nematolysosome and wrapping lysosome

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12 December 2020

Energy dependence of different steps in the autophagic-lysosomal pathway

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12 December 2020

Water, K+, H+, lactate and glucose fluxes during cell volume regulation in perfused rat liver

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12 December 2020

Regulation of protein turnover versus growth state. Studies on the mechanism(s) of initiation of acidic vacuolar proteolysis in cells of stationary ascites hepatoma

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12 December 2020

Immunoelectron microscopic localization of ubiquitin in hepatoma cells.

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12 December 2020

Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats

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12 December 2020

Characteristics of a glutamine carrier in skeletal muscle have important consequences for nitrogen loss in injury, infection, and chronic disease

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12 December 2020

Calcium-dependent proteases: an enzyme system active at cellular membranes?

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12 December 2020

Glucagon-induced autophagy and proteolysis in rat liver: mediation by selective deprivation of intracellular amino acids

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12 December 2020

Overall proteolysis in perfused and subfractionated chemically induced malignant hepatoma of rat: effects of amino acids

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12 December 2020

Intracellular protein catabolism: state of the art.

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12 December 2020

Liver autophagy in the influenza B virus model of Reye's syndrome in mice

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12 December 2020

Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver

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12 December 2020

Prelysosomal convergence of autophagic and endocytic pathways

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12 December 2020

Regulation of microautophagy and basal protein turnover in rat liver. Effects of short-term starvation

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12 December 2020

Modulation of the amino acid control of hepatic protein degradation by caloric deprivation. Two modes of alanine co-regulation.

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12 December 2020

Control of proteolysis in perifused rat hepatocytes

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12 December 2020

Multiphasic control of hepatic protein degradation by regulatory amino acids. General features and hormonal modulation

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12 December 2020

Use of a hydrolysable probe, [14C]lactose, to distinguish between pre-lysosomal and lysosomal steps in the autophagic pathway

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12 December 2020

Phosphorylation of ribosomal protein S6 by cAMP-dependent protein kinase and mitogen-stimulated S6 kinase differentially alters translation of globin mRNA.

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12 December 2020

Energy dependence of autophagic protein degradation in isolated rat hepatocytes

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12 December 2020

Quantitative changes in the lysosomal vacuolar system of rat hepatocytes during short-term starvation. A morphometric analysis with special reference to macro- and microautophagy.

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12 December 2020

Effect of glucagon: insulin ratios on hepatic metabolism

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12 December 2020

Mitochondrial Ultrastructure in Reye's Syndrome (Encephalopathy and Fatty Degeneration of the Viscera)

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12 December 2020

Sequestration of cytoplasmic enzymes in an autophagic vacuole-lysosomal system induced by injection of leupeptin

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12 December 2020

Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding

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12 December 2020

Degradation and turnover of peroxisomes in the yeast Hansenula polymorpha induced by selective inactivation of peroxisomal enzymes.

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12 December 2020

Lysosomes are associated with microtubules and not with intermediate filaments in cultured fibroblasts

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12 December 2020

Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver

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12 December 2020

Different effect of amino acid deprivation on syntheses of intra- and extracellular proteins in rat hepatocytes in primary culture

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12 December 2020

Inhibition by insulin of the formation of autophagic vacuoles in rat liver. A morphometric approach to the kinetics of intracellular degradation by autophagy

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12 December 2020

Amino acid control of autophagic sequestration and protein degradation in isolated rat hepatocytes

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12 December 2020

Uptake and degradation of proteins by isolated rat liver lysosomes. Suggestion of a microautophagic pathway of proteolysis

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12 December 2020

Differential phosphorylation of ribosomal protein S6 in isolated rat hepatocytes after incubation with insulin and glucagon

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12 December 2020

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

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12 December 2020

Accumulation of autophagosomes after inhibition of hepatocytic protein degradation by vinblastine, leupeptin or a lysosomotropic amine

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12 December 2020

Inhibition of autophagic vacuole formation and protein degradation by amino acids in isolated hepatocytes

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12 December 2020

Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes

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12 December 2020

Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.

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12 December 2020

Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation

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12 December 2020

Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions.

1 reference

12 December 2020

Rapamycin selectively inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor.

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12 December 2020

Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

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12 December 2020

Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)-phthalate treatment. III. Fusion of early autophagosomes with lysosomal compartments

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12 December 2020

Disruption of the cytokeratin cytoskeleton and inhibition of hepatocytic autophagy by okadaic acid.

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12 December 2020

Characterization of the swelling-induced alkalinization of endocytotic vesicles in fluorescein isothiocyanate-dextran-loaded rat hepatocytes

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12 December 2020

Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells

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12 December 2020

Phosphatidylinositol 3-kinase activity is required for early endosome fusion.

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12 December 2020

Catabolite inactivation of fructose-1,6-bisphosphatase of Saccharomyces cerevisiae. Degradation occurs via the ubiquitin pathway

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12 December 2020

Vanadate inhibition of hepatocytic autophagy. Calcium-modulated and osmolality-modulated antagonism by asparagine

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12 December 2020

Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis

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12 December 2020

Differentiation-dependent autophagy controls the fate of newly synthesized N-linked glycoproteins in the colon adenocarcinoma HT-29 cell line.

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12 December 2020

Ubiquitin and the enigma of intracellular protein degradation.

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12 December 2020

Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells

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12 December 2020

Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes

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12 December 2020

Ubiquitin in homeostasis, development and disease.

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12 December 2020

Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting.

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12 December 2020

Muscle wasting associated with cancer cachexia is linked to an important activation of the atp-dependent ubiquitin-mediated proteolysis

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12 December 2020

Divergent modes of autophagy in the methylotrophic yeast Pichia pastoris.

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12 December 2020

Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy

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12 December 2020

Inhibition of autophagy and multiple steps in asialoglycoprotein endocytosis by inhibitors of tyrosine protein kinases (tyrphostins).

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12 December 2020

Inhibition of proteolysis by cell swelling in the liver requires intact microtubular structures

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12 December 2020

Nascent polypeptide-associated complex protein prevents mistargeting of nascent chains to the endoplasmic reticulum

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12 December 2020

Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha

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12 December 2020

A heterotrimeric Gi3-protein controls autophagic sequestration in the human colon cancer cell line HT-29.

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12 December 2020

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

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12 December 2020

Regulation of ATP-ubiquitin-dependent proteolysis in muscle wasting.

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12 December 2020

Upstream mechanisms of glycogen synthase activation by insulin and insulin-like growth factor-I. Glycogen synthase activation is antagonized by wortmannin or LY294002 but not by rapamycin or by inhibiting p21ras

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12 December 2020

Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid

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12 December 2020

Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)phthalate treatment. II. Immunocytochemical analysis of early and late autophagosomes

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12 December 2020

Inhibition of macroautophagy and proteolysis in the isolated rat hepatocyte by a nontransportable derivative of the multiple antigen peptide Leu8-Lys4-Lys2-Lys-beta Ala

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12 December 2020

Cell swelling and the control of autophagic proteolysis in hepatocytes: involvement of phosphorylation of ribosomal protein S6?

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12 December 2020

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

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12 December 2020

Hsp70s and lysosomal proteolysis

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12 December 2020

Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.

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12 December 2020

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

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12 December 2020

Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin

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12 December 2020

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

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12 December 2020

Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

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12 December 2020

Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex

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12 December 2020

Calpain: new perspectives in molecular diversity and physiological-pathological involvement.

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12 December 2020

Leucine-specific binding of photoreactive Leu7-MAP to a high molecular weight protein on the plasma membrane of the isolated rat hepatocyte.

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12 December 2020

Specificity of leucine effect on protein degradation in perfused rat heart

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12 December 2020

Involvement of microtubules in the link between cell volume and pH of acidic cellular compartments in rat and human hepatocytes

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12 December 2020

Cellular hydration state: an important determinant of protein catabolism in health and disease

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12 December 2020

De novo autophagic vacuole formation in hepatocytes permeabilized by Staphylococcus aureus alpha-toxin. Inhibition by nonhydrolyzable GTP analogs.

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12 December 2020

Stimulation of translation in 3T3-L1 cells in response to insulin and phorbol ester is directly correlated with increased phosphate labelling of initiation factor (eIF-) 4F and ribosomal protein S6.

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12 December 2020

Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily.

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12 December 2020

Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization

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12 December 2020

Multiphasic control of proteolysis by leucine and alanine in the isolated rat hepatocyte.

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12 December 2020

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

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12 December 2020

[Lysosomes in the regulation of hormone secretion in the pituitary-adrenal gland axis]

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12 December 2020

Effect of cell volume on Acridine Orange fluorescence in hepatocytes

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12 December 2020

Formation of autophagosomes during degradation of excess peroxisomes induced by administration of dioctyl phthalate

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12 December 2020

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

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12 December 2020

Polypeptide import and degradation by isolated lysosomes

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12 December 2020

Dependence of hepatocytic autophagy on intracellularly sequestered calcium

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12 December 2020

Autophagic degradation of N-linked glycoproteins is downregulated in differentiated human colon adenocarcinoma cells.

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12 December 2020

Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.

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12 December 2020

Tissue protein turnover during liver carcinogenesis

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12 December 2020

Endocrine and amino acid regulation of liver macroautophagy and proteolytic function

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12 December 2020

The role of enzyme degradation in enzyme turnover during tissue differentiation

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12 December 2020

Selective autophagy of peroxisomes in methylotrophic yeasts

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12 December 2020

Cell swelling and the sensitivity of autophagic proteolysis to inhibition by amino acids in isolated rat hepatocytes

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12 December 2020

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

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12 December 2020

Effects of intracellular amino acid concentrations, cyclic AMP, and dexamethasone on lysosomal proteolysis in primary cultures of perinatal rat hepatocytes.

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12 December 2020

180-kD ribosome receptor is essential for both ribosome binding and protein translocation

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12 December 2020

Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle

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12 December 2020

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

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12 December 2020

Inhibition of hepatocytic autophagy by okadaic acid and other protein phosphatase inhibitors.

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12 December 2020

Evidence for acidity of prelysosomal autophagic/endocytic vacuoles (amphisomes).

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12 December 2020

Factors affecting secretory protein production in primary cultures of rat hepatocytes

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12 December 2020

Wortmannin inhibits transcytosis of dimeric IgA by the polymeric immunoglobulin receptor

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12 December 2020

The effects of wortmannin, a potent inhibitor of phosphatidylinositol 3-kinase, on insulin-stimulated glucose transport, GLUT4 translocation, antilipolysis, and DNA synthesis

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12 December 2020

Inhibition of autophagic proteolysis by cell swelling in hepatocytes

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12 December 2020

Cell hydration and proteolysis control in liver

1 reference

12 December 2020

Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids

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12 December 2020

A target for phosphoinositide 3-kinase: Akt/PKB.

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12 December 2020

Progressive cellular dehydration and proteolysis in critically ill patients

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12 December 2020

The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

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12 December 2020

The role of cellular hydration in the regulation of cell function

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12 December 2020

Regulation of vesicular pH in liver macrophages and parenchymal cells by ammonia and anisotonicity as assessed by fluorescein isothiocyanate-dextran fluorescence

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12 December 2020

The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway

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12 December 2020

Wortmannin-sensitive activation of p70s6k by endogenous and heterologously expressed Gi-coupled receptors

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12 December 2020

Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation

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12 December 2020

The metabolism of sphingo(glyco)lipids is correlated with the differentiation-dependent autophagic pathway in HT-29 cells.

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12 December 2020

The role of the intralysosomal pH in the control of autophagic proteolytic flux in rat hepatocytes.

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12 December 2020

A receptor for the selective uptake and degradation of proteins by lysosomes

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12 December 2020

Protein kinase signaling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes

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12 December 2020

Glutamine nutrition and metabolism: where do we go from here ?

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12 December 2020

The TOR signalling pathway and growth control in yeast

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12 December 2020

Responses of glutamine transport in cultured rat skeletal muscle to osmotically induced changes in cell volume

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12 December 2020

Phorbol esters stimulate phosphatidylinositol 3,4,5-trisphosphate production in 3T3-L1 adipocytes: implications for stimulation of glucose transport

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12 December 2020

p70 S6 kinase: an enigma with variations

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12 December 2020

Proteasomes: destruction as a programme

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12 December 2020

Guanine nucleotide exchange on heterotrimeric Gi3 protein controls autophagic sequestration in HT-29 cells.

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12 December 2020

The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes

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12 December 2020

Identifiers

DOI

10.1023/A:1026486801018

1 reference

1 October 2017

1 reference

PubMed ID

9184851