(Q41501775)

1 October 2017

1 reference

title

Covalent binding of xenobiotics to specific proteins in the liver (English)

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1 October 2017

Pumford NR

1

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1 October 2017

Halmes NC

series ordinal

2

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1 October 2017

Hinson JA

series ordinal

3

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1 October 2017

language of work or name

English

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publication date

1 February 1997

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1 October 2017

published in

Drug Metabolism Reviews

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1 October 2017

volume

29

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1 October 2017

issue

1-2

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1 October 2017

page(s)

39-57

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An immunochemical approach of identifying and characterizing protein targets of toxic reactive metabolites

1 October 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Immunochemical detection of liver protein adducts of the nonsteroidal antiinflammatory drug diclofenac

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Immunochemical detection of protein adducts in mice treated with trichloroethylene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Immunochemical analysis of acetaminophen covalent binding to proteins. Partial characterization of the major acetaminophen-binding liver proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Purification, antibody production, and partial amino acid sequence of the 58-kDa acetaminophen-binding liver proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

DNA sequencing of a mouse liver protein that binds selenium: implications for selenium's mechanism of action in cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Different patterns of regulation of the genes encoding the closely related 56 kDa selenium- and acetaminophen-binding proteins in normal tissues and during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Identification of the mouse liver 44-kDa acetaminophen-binding protein as a subunit of glutamine synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Mitochondrial dysfunction in paracetamol hepatotoxicity: in vitro studies in isolated mouse hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Evidence for expression in human liver of halothane-induced neoantigens recognized by antibodies in sera from patients with halothane hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Glutathione-S-transferase is a target for covalent modification by a halothane reactive intermediate in the guinea pig liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Diclofenac-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Fatal hepatitis associated with diclofenac

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Diclofenac-associated hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Diclofenac associated hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Metabolism, toxicity, and carcinogenicity of trichloroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Consideration of the Target Organ Toxicity of Trichloroethylene in Terms of Metabolite Toxicity and Pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

A new syndrome with pigmentation, scleroderma, gynaecomastia, Raynaud's phenomenon and peripheral neuropath

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Prevalence of symptoms of systemic lupus erythematosus (SLE) and of fluorescent antinuclear antibodies associated with chronic exposure to trichloroethylene and other chemicals in well water

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Chloroethylenes: a mechanistic approach to human risk evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

A metabolite of halothane covalently binds to an endoplasmic reticulum protein that is highly homologous to phosphatidylinositol-specific phospholipase C-alpha but has no activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

cDNA cloning and baculovirus expression of the human liver endoplasmic reticulum P58: characterization as a protein disulfide isomerase isoform, but not as a protease or a carnitine acyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Human anti-endoplasmic reticulum antibodies in sera of patients with halothane-induced hepatitis are directed against a trifluoroacetylated carboxylesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

The calcium-binding protein calreticulin is covalently modified in rat liver by a reactive metabolite of the inhalation anesthetic halothane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Serum antibodies from halothane hepatitis patients react with the rat endoplasmic reticulum protein ERp72.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

UDP-glucose:glycoprotein glucosyltransferase associates with endoplasmic reticulum chaperones and its activity is decreased in vivo by the inhalation anesthetic halothane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

Formation and identification of protein adducts to cytosolic proteins in guinea pig liver slices exposed to halothane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539709037572

10.3109/03602539709037572

21 January 2018

Identifiers

DOI

1 reference

1 October 2017

1 reference