(Q37008371)

17 August 2017

title

Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics (English)

1 reference

17 August 2017

Consideration of the Target Organ Toxicity of Trichloroethylene in Terms of Metabolite Toxicity and Pharmacokinetics (English)

1 reference

https://api.crossref.org/works/10.3109/03602539109029772

29 November 2022

0 references

1 reference

I. W. Davidson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1802654

29 November 2022

R. P. Beliles

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1802654

29 November 2022

publication date

1 January 1991

1 reference

full work available at URL

17 August 2017

language of work or name

English

0 references

http://www.tandfonline.com/doi/pdf/10.3109/03602539109029772

1 reference

https://api.crossref.org/works/10.3109/03602539109029772

29 November 2022

published in

Drug Metabolism Reviews

1 reference

17 August 2017

volume

23

1 reference

17 August 2017

issue

5-6

1 reference

17 August 2017

page(s)

493-599

1 reference

publication type of scholarly work

17 August 2017

review article

1 reference

Quantitative evaluation of the metabolic interactions between trichloroethylene and 1,1-dichloroethylene in vivo using gas uptake methods

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Chronic trichloroethylene intoxication: a new approach by trigeminal-evoked potentials?

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Interaction of bishydroxycoumarin with chloral hydrate and trichloroethyl phosphate

21 January 2018

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Interactions of trichloroethylene with DNA in vitro and with RNA and DNA of various mouse tissues in vivo

21 January 2018

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Application and Results of Whole-Body Autoradiography in Distribution Studies of Organic Solvents

21 January 2018

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Causes of death among laundry and dry cleaning workers

21 January 2018

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Irreversible binding of chlorinated ethylenes to macromolecules

21 January 2018

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Incubation of 14C-trichloroethylene vapor with rat liver microsomes: uptake of radioactivity and covalent protein binding of metabolites

21 January 2018

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Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation

21 January 2018

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Chemical reactivity, biotransformation, and toxicity of polychlorinated aliphatic compounds

21 January 2018

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Adverse effects of volatile anaesthetics

21 January 2018

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Metabolism, toxicity, and carcinogenicity of trichloroethylene.

21 January 2018

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Delineation of the role of metabolism in the hepatotoxicity of trichloroethylene and perchloroethylene: a dose-effect study

21 January 2018

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Association between clinical symptoms and lymphocyte abnormalities in a population with chronic domestic exposure to industrial solvent-contaminated domestic water supply and a high incidence of leukaemia

21 January 2018

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Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography

21 January 2018

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Identification of N-acetyl(2,2-dichlorovinyl)- and N-acetyl(1,2-dichlorovinyl)-L-cysteine as two regioisomeric mercapturic acids of trichloroethylene in the rat.

21 January 2018

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Ethanol potentiation of halogenated aliphatic solvent toxicity

21 January 2018

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Influence of aliphatic alcohols on the hepatic response to halogenated olefins

21 January 2018

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Metabolism of trichloroethylene by the isolated perfused lung

21 January 2018

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THE METABOLISM OF 36C1-LABELLED TRICHLOROETHYLENE AND TETRACHLOROETHYLENE IN THE RAT.

21 January 2018

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Chloroform: a review of its metabolism, teratogenic, mutagenic, and carcinogenic potential

21 January 2018

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Biological basis for extrapolation across mammalian species

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Novel metabolites of trichloroethylene through dechlorination reactions in rats, mice and humans

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Absorption, elimination and metabolism of trichloroethylene: a quantitative comparison between rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase

21 January 2018

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Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Cardiac irregularities due to trichlorethylene given during labour

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

ANAESTHETIC SOLUBILITY IN BLOOD AND TISSUES: VALUES AND SIGNIFICANCE

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

The pharmacokinetics of metabolism of inhalation anaesthetics. A simulation study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Blink reflex latency after exposure to trichloroethylene in well water

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Physiologically based pharmacokinetic modeling of the lactating rat and nursing pup: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Detection of a cellular oncogene in spontaneous liver tumors of B6C3F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Inhalation carcinogenicity of trichloroethylene in mice and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

A physiologically based simulation approach for determining metabolic constants from gas uptake data

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

An association of human congenital cardiac malformations and drinking water contaminants

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Chloroethylenes: a mechanistic approach to human risk evaluation

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Species differences in response to trichloroethylene. II. Biotransformation in rats and mice

21 January 2018

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Mutagenicity and chromosomal aberrations as an analytical tool for in vitro detection of mammalian enzyme-mediated formation of reactive metabolites

21 January 2018

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Consideration of the evidence for mechanisms of 1,1,2-trichloroethylene metabolism, including new identification of its dichloroacetic acid and trichloroacetic acid metabolites in mice

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Trichlorethylene anaesthesia

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Reactions of trichloroethylene epoxide in aqueous systems

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Carcinogenicity study of trichloroethylene by longterm inhalation in three animal species

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice

21 January 2018

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Carcinogenicity of trichloroethylene: fact or artifact?

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Metabolism of trichloroethylene and tetrachloroethylene in human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Metabolism of trichloroethylene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Uptake via the blood and elimination of 10 organic solvents following epicutaneous exposure of anesthetized guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Trichloroethylene: effects on body and organ weights in mice, rats and gerbils.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Effects of long‐term exposure to trichloroethylene on the behavior of mongolian gerbils (meriones unguiculatus)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Relative effects of various chlorinated hydrocarbons on liver and kidney function in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Hepatotoxic Effect of Tri- and Tetra-chlorethylene on Mice

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Effect of inhaled trichloroethylene on the CNS. As measured by optokinetic nystagmus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Vinyl chloride and trichloroethylene: Comparison of alkylating effects of metabolites and induction of preneoplastic enzyme deficiencies in rat liver

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Common-source community and industrial exposure to trichloroethylene

21 January 2018

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"Danger--vapor harmful": spot-remover sniffing

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

ACUTE TRICHLOROETHYLENE NARCOSIS. ACCIDENT INVOLVING THE USE OF TRICHLOROETHYLENE IN A CONFINED SPACE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Effects of oral exposure to trichloroethylene on female reproductive function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Enhancement of DMN-induced kidney tumors by 1,2-dichlorovinylcysteine in Swiss-Webster mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Oxidation of trichloroethylene by liver microsomal cytochrome P-450: evidence for chlorine migration in a transition state not involving trichloroethylene oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539109029772

Difference in uptake, elimination, and metabolism in exposure to trichloroethylene, 1,1,1-trichloroethane and tetrachloroethylene

21 January 2018

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Pharmacokinetics of trichloroethylene in volunteers, influence of workload and exposure concentration

21 January 2018

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Kinetics of 1,1,1-trichloroethane in volunteers; Influence of exposure concentration and work load

21 January 2018

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Enhancement of the metabolism and hepatotoxicity of trichloroethylene and perchloroethylene

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Metabolism of trichloroethylene in man. II. Pharmacokinetics of metabolites

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Metabolism of trichloroethylene in man. III. Interaction of trichloroethylene and ethanol

21 January 2018

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Dietary modification of metabolism and toxicity of chemical substances--with special reference to carbohydrate

21 January 2018

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Acetaldehyde level in the blood and liver aldehyde dehydrogenase activities in trichloroethylene-treated rats

21 January 2018

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Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo

21 January 2018

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Dose-response relationship for trichloroethylene in man.

21 January 2018

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Metabolism of [14C]trichloroethylene to 14CO2 and interaction of a metabolite with liver DNA in rats and mice

21 January 2018

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Inhibition, activation, destruction, and induction of drug-metabolizing enzymes by trichloroethylene

21 January 2018

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Distribution of volatile halogenated organic compounds between rat blood serum and adipose tissue

21 January 2018

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Stevens-Johnson syndrome associated with occupational exposure to trichloroethylene

21 January 2018

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Effects on experimental animals of long-term inhalation of trichloroethylene, carbon tetrachloride, 1,1,1-trichloroethane, dichlorodifluoromethane, and 1,1-dichloroethylene

21 January 2018

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Species differences in response to trichloroethylene. I. Pharmacokinetics in rats and mice

21 January 2018

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Damage to hepatic cellular membranes by chlorinated olefins with emphasis on synergism and antagonism

21 January 2018

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Chemically induced nephrotoxicity: role of metabolic activation

21 January 2018

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A new syndrome with pigmentation, scleroderma, gynaecomastia, Raynaud's phenomenon and peripheral neuropath

21 January 2018

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Humoral and cell-mediated immune status in mice exposed to trichloroethylene in the drinking water

21 January 2018

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Accumulation kinetics of trichloroethylene and its metabolites during multiple exposures. A theoretical study (author's transl)

21 January 2018

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Trichloroethylene and 1,1,1-trichloroethane: effects on brain and liver after five days intermittent inhalation

21 January 2018

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Interaction of chloral hydrate and ethanol in man: I. Metabolism

21 January 2018

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Teratogenic activity of trichloroacetic acid in the rat.

21 January 2018

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Range-Finding Toxicity Data: List VII

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Observations on the Concentrations of Trichloroethylene in Blood and Expired Air Following Exposure of Humans

21 January 2018

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ABSORPTION OF CARBON TETRACHLORIDE, TRICHLOROETHYLENE, TETRACHLOROETHYLENE, METHYLENE CHLORIDE, AND 1,1,1-TRICHLOROETHANE THROUGH THE HUMAN SKIN.

21 January 2018

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Experimental Human Exposure to Trichloroethylene

21 January 2018

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Use of breath analysis to monitor trichloroethylene exposures

21 January 2018

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"Degreasers' flush:" dermal response to trichloroethylene and ethanol

21 January 2018

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Further studies on the site and mechanism of action of s-(1,2 dichlorovinyl)-l-systeine and s-(1,2 dichlorovinyl)-3-mercaptopropionic acid in rat liver

21 January 2018

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The pharmacokinetics and macromolecular interactions of trichloroethylene in mice and rats

21 January 2018

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Genetic and nongenetic events in neoplasia

21 January 2018

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Reduction of chloral hydrate to trichloroethanol in brain extracts

21 January 2018

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The subcellular distribution and properties of aldehyde dehydrogenases in rat liver

21 January 2018

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Toxicology of trichloroethylene in the mouse

21 January 2018

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Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro

21 January 2018

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Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation

21 January 2018

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Mutagenicity of amino acid and glutathione S-conjugates in the Ames test

21 January 2018

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Dechloriation mechanisms of chlorinated olefins

21 January 2018

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Do solvents cause scleroderma?

21 January 2018

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Trichloroethylene. I. An overview

21 January 2018

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The action of trichlorethylene on the cardiovascular system

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Epinephrine-induced cardiac arrhythmias in rabbits exposed to trichloroethylene: Potentiation by ethanol

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Cardiac arrhythmias due to chloral hydrate poisoning

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Effects of trichloroethylene exposure on male reproductive function in rats

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Determination of the kinetic constants for metabolism of inhaled toxicants in vivo using gas uptake measurements

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539109029772

Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens

21 January 2018

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Cleavage of S-(1,2-dichlorovinyl)-l-cysteine by an enzyme of bovine origin

21 January 2018

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A Cohort Study on Trichloroethylene Exposure and Cancer Mortality

29 November 2022

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Reactions of vinyl chloride with RNA and DNA of various mouse tissues in vivo

29 November 2022

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Properties of DNA treated with S-(1,2-dichlorovinyl)-L-cysteine and a lyase

29 November 2022

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Human liver aldehyde dehydrogenase: partial purification and properties

29 November 2022

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Reactive metabolites and carcinogenicity of halogenated ethylenes

29 November 2022

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Chloral hydrate overdose and cardiac arrhythmias

29 November 2022

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29 November 2022

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29 November 2022

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Pharmacokinetics of halogenated ethylenes in rats

29 November 2022

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The relation between inhaled and exhaled trichlorethylene and trichloracetic acid excreted in the urine of rats exposed to trichlorethylene.

29 November 2022

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Biotransformation of trichloroethylene.

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17 August 2017

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