(Q41504616)

English

Physiologically based modeling of the pharmacokinetics of acetaminophen and its major metabolites in humans using a Bayesian population approach.

scientific article published on 31 January 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Physiologically based modeling of the pharmacokinetics of acetaminophen and its major metabolites in humans using a Bayesian population approach (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Todd J Zurlinden

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

2

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Todd J Zurlinden

1

1 reference

Europe PubMed Central

PubMed publication ID

1 October 2017

Brad Reisfeld

2

1 reference

Europe PubMed Central

PubMed publication ID

1 October 2017

publication date

31 January 2015

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

European Journal of Drug Metabolism and Pharmacokinetics

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

41

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29 February 2020

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

267-280

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

GNU MCSim: Bayesian statistical inference for SBML-coded systems biology models.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Physiological parameter values for physiologically based pharmacokinetic models

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Physiologically based pharmacokinetic/toxicokinetic modeling

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Single-dose pharmacokinetics of paracetamol and its conjugates in Chinese non-insulin-dependent diabetic patients with renal impairment.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

The comparative pharmacokinetics of modified-release and immediate-release paracetamol in a simulated overdose model

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Kinetics of acetaminophen absorption and gastric emptying in man

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

The role of sulphate conjugation in the metabolism and disposition of oral and intravenous paracetamol in man.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Inter-subject and ethnic differences in paracetamol metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Differences in the single-oral-dose pharmacokinetics and urinary excretion of paracetamol and its conjugates between Hong Kong Chinese and Caucasian subjects

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Development and evaluation of a generic physiologically based pharmacokinetic model for children.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Paracetamol metabolism in two ethnically different Spanish populations

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Clinical pharmacokinetics of paracetamol

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Matplotlib: A 2D Graphics Environment

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Effect of nizatidine on paracetamol and its metabolites in human plasma

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Is biliary excretion of paracetamol significant in man?

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

The quantification of paracetamol, paracetamol glucuronide and paracetamol sulphate in plasma and urine using a single high-performance liquid chromatography assay.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Effects of imatinib mesylate on the pharmacokinetics of paracetamol (acetaminophen) in Korean patients with chronic myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Quantitation of small intestinal permeability during normal human drug absorption

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Dose-dependent pharmacokinetics: experimental observations and theoretical considerations

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Computational toxicology of chloroform: reverse dosimetry using Bayesian inference, Markov chain Monte Carlo simulation, and human biomonitoring data.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Sulfotransferase (SULT) 1A1 polymorphic variants *1, *2, and *3 are associated with altered enzymatic activity, cellular phenotype, and protein degradation

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Utility of Hepatocytes in Predicting Drug Metabolism: Comparison of Hepatic Intrinsic Clearance in Rats and Humans in Vivo and in Vitro

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Prediction of dose-hepatotoxic response in humans based on toxicokinetic/toxicodynamic modeling with or without in vivo data: a case study with acetaminophen.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Kinetics and metabolism of paracetamol and phenacetin

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Paracetamol disposition and metabolite kinetics in patients with chronic renal failure

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Assessment of cryopreserved human hepatocytes as a model system to investigate sulfation and glucuronidation and to evaluate inhibitors of drug conjugation

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Physiologically based pharmacokinetic modelling 2: predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Acetaminophen hepatotoxicity: the first 35 years

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Pharmacokinetics/pharmacodynamics of acetaminophen analgesia in Japanese patients with chronic pain

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

A level A in vitro/in vivo correlation in fasted and fed states using different methods: applied to solid immediate release oral dosage form

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Application of physiologically based pharmacokinetic models for assessing drug disposition in space

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Quantification of acetaminophen and two of its metabolites in human plasma by ultra-high performance liquid chromatography-low and high resolution tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Introduction to pharmacokinetics in clinical toxicology.

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

HMDB 3.0--The Human Metabolome Database in 2013

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Pharmacokinetics of acetaminophen in Hong Kong Chinese subjects

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

The NumPy Array: A Structure for Efficient Numerical Computation

1 reference

https://api.crossref.org/works/10.1007%2FS13318-015-0253-X

21 January 2018

Determination of blood and other tissue concentrations of paracetamol in dog and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of probenecid on paracetamol metabolism and pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of acetaminophen glucuronidation by UDP-glucuronosyltransferases 1A1, 1A6, 1A9 and 2B15. Potential implications in acetaminophen-induced hepatotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistently increased acetaminophen concentrations in a patient with acute liver failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple-Dose Acetaminophen Pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetaminophen decreases adenosine 3'-phosphate 5'-phosphosulfate and uridine diphosphoglucuronic acid in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of acetaminophen conjugates in isolated rat hepatocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of paracetamol (acetaminophen) after intravenous and oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The estimation of paracetamol and its major metabolites in both plasma and urine by a single high-performance liquid chromatography assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous quantitative determination of paracetamol and its glucuronide conjugate in human plasma and urine by liquid chromatography coupled to electrospray tandem mass spectrometry: application to a clinical pharmacokinetic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of pharmacokinetics and metabolism in drug discovery and development

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The disposition of paracetamol and its conjugates during multiple dosing in patients with end-stage renal failure maintained on haemodialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucuronidation and biliary excretion of acetaminophen in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-dependent pharmacokinetics and first-pass metabolism of acetaminophen in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatographic determination of acetaminophen in plasma: single-dose pharmacokinetic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25636597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13318-015-0253-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

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24 November 2022

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25636597%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

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