(Q41512249)

1 October 2017

5 references

31 July 2019

19 September 2019

12 October 2019

18 October 2019

26 August 2020

Understanding the mechanisms of sustained signaling and T cell activation (English)

1 reference

biomedical investigative technique

1 October 2017

1 reference

31 July 2019

1 reference

19 September 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

1 reference

26 August 2020

A Lanzavecchia

1

1 reference

PMCID

2196326

1 October 2017

language of work or name

English

0 references

publication date

1 May 1997

1 reference

PMCID

2196326

1 October 2017

19 May 1997

5 references

31 July 2019

19 September 2019

12 October 2019

18 October 2019

26 August 2020

3

1 reference

Journal of Experimental Medicine

inferred from page(s)

published in

6 references

1 October 2017

31 July 2019

19 September 2019

12 October 2019

18 October 2019

26 August 2020

185

1 reference

1 October 2017

1717-1719

1 reference

1 October 2017

10

1 reference

Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Kinetics and extent of T cell activation as measured with the calcium signal

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Early biochemical signals arise from low affinity TCR-ligand reactions at the cell-cell interface

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Partial signaling by CD8+ T cells in response to antagonist ligands

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

T cell activation determined by T cell receptor number and tunable thresholds.

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Essential flexibility in the T-cell recognition of antigen

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

High sensitivity, low affinity--paradox of T-cell receptor recognition

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

The minimal number of class II MHC-antigen complexes needed for T cell activation

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

10 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196326

Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.185.10.1717

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9198667

12 December 2020

inferred from PubMed ID database lookup

A cell culture model for T lymphocyte clonal anergy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9198667

12 December 2020

inferred from PubMed ID database lookup

Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9198667

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1084/JEM.185.10.1717

1 reference

1 October 2017

1 reference

1 October 2017

1 reference

PMCID

2196326