(Q41515240)

2 October 2017

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title

Genetics of apoptosis (English)

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2 October 2017

Genetics of Apoptosis (English)

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author

Michael Otmar Hengartner

object named as

Michael O. Hengartner

2

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author name string

Desnoyers S

1

1 reference

2 October 2017

Hengartner MO

2

1 reference

2 October 2017

Serge Desnoyers

1

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publication date

1 January 1997

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2 October 2017

1997

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published in

Advances in Pharmacology

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2 October 2017

41

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2 October 2017

35-56

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Death in Embryonic Systems

2 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Delayed internucleosomal DNA fragmentation in programmed cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cell death during development of the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Molecular mechanisms of developmental neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Programmed cell death in the immune system.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cell death mechanisms and the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The embryonic cell lineage of the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Genetic control of programmed cell death in the nematode C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Neuronal cell lineages in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

A genetic pathway for the development of the Caenorhabditis elegans HSN motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Molecular cloning of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Interleukin 1 beta (IL-1 beta) processing in murine macrophages requires a structurally conserved homologue of human IL-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Prevention of vertebrate neuronal death by the crmA gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Molecular regulation of apoptosis: genetic controls on cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Programmed cell death in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

dad-1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The essential OST2 gene encodes the 16-kD subunit of the yeast oligosaccharyltransferase, a highly conserved protein expressed in diverse eukaryotic organisms

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Inhibition of N-linked glycosylation induces early apoptosis in human promyelocytic HL-60 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cell death: the significance of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Fine structure of degenerating abdominal motor neurons after eclosion in the sphingid moth, Manduca sexta

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Post-embryonic development in the ventral cord of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

An endonuclease from Caenorhabditis elegans: partial purification and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The emergence of order in the Drosophila pupal retina.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Genetic control of programmed cell death in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Homology between reaper and the cell death domains of Fas and TNFR1

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The death domain: a module shared by proteins with diverse cellular functions.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cell killing by the Drosophila gene reaper

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Expression of the baculovirus p35 gene inhibits mammalian neural cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The head involution defective gene of Drosophila melanogaster functions in programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

grim, a novel cell death gene in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Life, death, and the pursuit of apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Induction of apoptosis by the Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The role of proteases during apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Viruses and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Mutations in the gene encoding the adenovirus early region 1B 19,000-molecular-weight tumor antigen cause the degradation of chromosomal DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The E1b oncogene of adenovirus confers cellular resistance to cytotoxicity of tumor necrosis factor and monoclonal anti-Fas antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The 19-Kilodalton Adenovirus E1B Transforming Protein Inhibits Programmed Cell Death and Prevents Cytolysis by Tumor Necrosis Factor α

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Epstein-Barr virus-infected B cells persist in the circulation of acyclovir-treated virus carriers

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Eradication of Epstein-Barr virus by allogeneic bone marrow transplantation: implications for sites of viral latency

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Apoptosis and programmed cell death in immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Prevention of apoptosis by a baculovirus gene during infection of insect cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Control of programmed cell death by the baculovirus genes p35 and iap.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Suppression of apoptosis in insect cells stably transfected with baculovirus p35: dominant interference by N-terminal sequences p35(1-76).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Identification and characterization of a spinal muscular atrophy-determining gene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Programmed cell death in bacterial populations

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Programmed nuclear death: apoptotic-like degradation of specific nuclei in conjugating Tetrahymena

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Genetic variation in pathogenic bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Selfish behavior of restriction-modification systems

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

Mechanisms and Functions of Cell Death

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2961053-4

7 January 2021

10.1016/S1054-3589(08)61053-4

Identifiers

DOI

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1 reference