(Q41526041)

2 October 2017

1 reference

title

Toxicity of nonsteroidal anti-inflammatory drugs in the elderly: is advanced age a risk factor? (English)

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2 October 2017

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2

Gurwitz JH

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2 October 2017

Solomon DH

1

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PubMed ID

9217572

2 October 2017

language of work or name

English

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publication date

1 February 1997

1 reference

American Journal of Medicine

2 October 2017

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2 October 2017

102

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2 October 2017

2

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2 October 2017

208-215

1 reference

Prevalence and characteristics of multiple analgesic drug use in an elderly study group.

2 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Evaluating drugs after their approval for clinical use

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

7 January 2021

1 reference

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Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

7 January 2021

1 reference

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Renal syndromes associated with nonsteroidal antiinflammatory drugs

7 January 2021

1 reference

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Nonsteroidal anti-inflammatory drugs and peptic ulcer disease

7 January 2021

1 reference

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Aging and heparin-related bleeding

7 January 2021

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Benzodiazepines of long and short elimination half-life and the risk of hip fracture

7 January 2021

1 reference

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Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations (Part I).

7 January 2021

1 reference

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Implications of altered drug disposition in the elderly: studies of benzodiazepines

7 January 2021

1 reference

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Clinical Pharmacokinetics of Non-steroidal Anti-inflammatory Drugs

7 January 2021

1 reference

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The pharmacokinetics of non-steroidal anti-inflammatory drugs in the elderly

7 January 2021

1 reference

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Absorption and disposition of ibuprofen in the elderly

7 January 2021

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Effects of age on the clinical pharmacokinetics of ibuprofen

7 January 2021

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Naproxen pharmacokinetics in the elderly

7 January 2021

1 reference

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Pharmacokinetics of naproxen in elderly patients

7 January 2021

1 reference

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Steady state pharmacokinetics of naproxen in elderly rheumatics compared with young volunteers

7 January 2021

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Pharmacokinetics of ketoprofen in the elderly

7 January 2021

1 reference

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Pharmacokinetic profile of controlled release ketoprofen in elderly patients

7 January 2021

1 reference

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A multiple dose pharmacokinetic and tolerance study of once daily 200 mg sustained-release flurbiprofen capsules in young and very elderly patients

7 January 2021

1 reference

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Oxaprozin pharmacokinetics in the elderly

7 January 2021

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Pharmacokinetic projections for isoxicam and piroxicam in old and young subjects

7 January 2021

1 reference

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Factors affecting the kinetics of two benzothiazine non-steroidal anti-inflammatory medicines, piroxicam and isoxicam

7 January 2021

1 reference

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Effects of age and sex on piroxicam disposition

7 January 2021

1 reference

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Pharmacokinetic observations on piroxicam in young adult, middle-aged and elderly patients

7 January 2021

1 reference

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Single-dose and steady-state pharmacokinetics of piroxicam in elderly vs young adults

7 January 2021

1 reference

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The pharmacokinetics of piroxicam in elderly persons with and without renal impairment

7 January 2021

1 reference

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Effects of age and disease on the pharmacokinetics and pharmacodynamics of sulindac

7 January 2021

1 reference

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Etodolac kinetics in the elderly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Steady state pharmacokinetic profile of indomethacin in elderly patients and young volunteers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Pharmacokinetics of indomethacin in the elderly

7 January 2021

1 reference

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A pharmacokinetic study of the active metabolite of nabumetone in young healthy subjects and older arthritis patients

7 January 2021

1 reference

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Nabumetone kinetics in the young and elderly

7 January 2021

1 reference

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Effects of nabumetone on prostanoid biosynthesis in humans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Pharmacokinetics of Salicylates in Elderly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Influence of renal failure, rheumatoid arthritis and old age on the pharmacokinetics of diflunisal

7 January 2021

1 reference

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The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

PGH synthase isoenzyme selectivity: the potential for safer nonsteroidal antiinflammatory drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Nonsteroidal antiinflammatory drugs and the gastrointestinal tract. The double-edged sword

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Some of the factors that may mediate or modify the gastrointestinal mucosal damage induced by non-steroidal anti-inflammatory drugs

7 January 2021

1 reference

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The relative gastrointestinal toxicity of the nonsteroidal anti-inflammatory drugs

7 January 2021

1 reference

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Parenteral ketorolac and risk of gastrointestinal and operative site bleeding. A postmarketing surveillance study

7 January 2021

1 reference

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Free radicals and lipid peroxidation in ethanol- or aspirin-induced gastric mucosal injury

7 January 2021

1 reference

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Biochemical gastroprotection from acute ulceration induced by aspirin and related drugs

7 January 2021

1 reference

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The role of arachidonic acid metabolites in gastrointestinal homeostasis. Biochemical, histological and clinical gastrointestinal effects

7 January 2021

1 reference

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Duodenal bicarbonate secretion in humans. Role of prostaglandins

7 January 2021

1 reference

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Role of endogenous prostaglandins in preventing gastrointestinal ulceration: induction of ulcers by antibodies to prostaglandins.

7 January 2021

1 reference

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Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial

7 January 2021

1 reference

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Double-blind, placebo-controlled endoscopic comparison of the mucosal protective effects of misoprostol versus cimetidine on tolmetin-induced mucosal injury to the stomach and duodenum

7 January 2021

1 reference

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Misoprostol compared with sucralfate in the prevention of nonsteroidal anti-inflammatory drug-induced gastric ulcer. A randomized, controlled trial

7 January 2021

1 reference

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Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial

7 January 2021

1 reference

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Lipid peroxidation and free radical scavengers in Alzheimer's disease

7 January 2021

1 reference

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7 January 2021

1 reference

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Age-associated decreases in prostaglandin contents in human gastric mucosa

7 January 2021

1 reference

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Effects of aging on responses to furosemide

7 January 2021

1 reference

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7 January 2021

1 reference

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The influence of age on renal prostaglandin synthesis in man.

7 January 2021

1 reference

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Effect of aging on 6-keto-PGF1 alpha levels in normotensive and essential hypertensive males

7 January 2021

1 reference

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The effect of age on circulating 6-keto-prostaglandin F1 alpha in humans

7 January 2021

1 reference

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Reduction of aspirin-induced gastroduodenal mucosal damage with ranitidine

7 January 2021

1 reference

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Protective effect of sucralfate against aspirin-induced damage to the human gastric mucosa

7 January 2021

1 reference

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Aspirin use in patients with major upper gastrointestinal bleeding and peptic-ulcer disease. A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9343%2896%2900380-4

Nonsteroidal anti-inflammatory drugs and gastrointestinal bleeding. A case-control study

7 January 2021

1 reference

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Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer

7 January 2021

1 reference

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The association of nonsteroidal anti-inflammatory drugs with upper gastrointestinal tract bleeding

7 January 2021

1 reference

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Risk of acute upper gastrointestinal bleeding in patients with ulcerative disease and treatment with non-steroidal anti-inflammatory drugs (NSAIDs). Results from the Comprehensive Hospital Drug Monitoring Berne (CHDM)

7 January 2021

1 reference

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Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons

7 January 2021

1 reference

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Risk for Serious Gastrointestinal Complications Related to Use of Nonsteroidal Anti-inflammatory Drugs

7 January 2021

1 reference

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Non-steroidal anti-inflammatory drugs and peptic ulcer perforation

7 January 2021

1 reference

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Nonsteroidal anti-inflammatory drug use and death from peptic ulcer in elderly persons

7 January 2021

1 reference

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Fatal upper gastrointestinal hemorrhage or perforation among users and nonusers of nonsteroidal anti-inflammatory drugs in Saskatchewan, Canada 1983

7 January 2021

1 reference

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Non-steroidal anti-inflammatory drug ingestion: retrospective study of 272 bleeding or perforated peptic ulcers

7 January 2021

1 reference

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Upper gastrointestinal bleeding in relation to previous use of analgesics and non-steroidal anti-inflammatory drugs

7 January 2021

1 reference

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Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin: a case-control study

7 January 2021

1 reference

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Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons

7 January 2021

1 reference

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Risk of upper gastrointestinal bleeding and perforation associated with Individual non-steroidal anti-inflammatory drugs

7 January 2021

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Renal prostaglandins, effective renal plasma flow and glomerular filtration rate in healthy elderly subjects

7 January 2021

1 reference

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A study of manufacturer-supported trials of nonsteroidal anti-inflammatory drugs in the treatment of arthritis

7 January 2021

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L-745,337: a selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats

7 January 2021

1 reference

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NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions

7 January 2021

1 reference

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A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats

7 January 2021

1 reference

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Pharmacokinetic Studies on Diclofenac Sodium in Young and Old Volunteers

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0002-9343(96)00380-4

1 reference

2 October 2017

1 reference

PubMed ID

9217572