(Q41554894)

3 October 2017

OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution (English)

1 reference

3 October 2017

7

Patrick Yu-Wai-Man

1 reference

3 October 2017

14

Patrick F Chinnery

1 reference

3 October 2017

0 references

16

Valerio Carelli

1 reference

3 October 2017

Ghizlane Elachouri

1

1 reference

3 October 2017

Sara Vidoni

2

1 reference

3 October 2017

Claudia Zanna

3

1 reference

3 October 2017

Alexandre Pattyn

4

1 reference

3 October 2017

Hassan Boukhaddaoui

5

1 reference

3 October 2017

Karen Gaget

6

1 reference

3 October 2017

Giuseppe Gasparre

8

1 reference

3 October 2017

Emmanuelle Sarzi

9

1 reference

3 October 2017

Cécile Delettre

10

1 reference

3 October 2017

Aurélien Olichon

11

1 reference

3 October 2017

Dominique Loiseau

12

1 reference

3 October 2017

Pascal Reynier

13

1 reference

3 October 2017

Agnès Rotig

15

1 reference

3 October 2017

Christian P Hamel

17

1 reference

3 October 2017

Michela Rugolo

18

1 reference

3 October 2017

Guy Lenaers

19

1 reference

3 October 2017

language of work or name

1 reference

25 October 2010

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3 October 2017

1 reference

3 October 2017

21

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3 October 2017

1

1 reference

3 October 2017

12-20

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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

3 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

The layered structure of human mitochondrial DNA nucleoids

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Inherited mitochondrial diseases of DNA replication

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mammalian mitochondrial nucleoids: organizing an independently minded genome.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Chromosome organization and segregation in bacteria

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Critical dependence of neurons on mitochondrial dynamics

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Organization, dynamics and transmission of mitochondrial DNA: focus on vertebrate nucleoids.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Two-step cross-linking method for identification of NF-kappaB gene network by chromatin immunoprecipitation.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Processing of Mgm1 by the Rhomboid-type Protease Pcp1 Is Required for Maintenance of Mitochondrial Morphology and of Mitochondrial DNA

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Composition and dynamics of human mitochondrial nucleoids

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mutation spectrum and splicing variants in the OPA1 gene

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Normal mitochondrial structure and genome maintenance in yeast requires the dynamin-like product of the MGM1 gene.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Association of a protein structure of probable membrane derivation with HeLa cell mitochondrial DNA near its origin of replication

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mitochondrial bioenergetic background confers a survival advantage to HepG2 cells in response to chemotherapy.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Molecular screening of 980 cases of suspected hereditary optic neuropathy with a report on 77 novel OPA1 mutations.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Disorders from perturbations of nuclear-mitochondrial intergenomic cross-talk.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mitochondrial fusion protects against neurodegeneration in the cerebellum.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Mitochondrial DNA depletion is a prevalent cause of multiple respiratory chain deficiency in childhood

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

A replicating module as the unit of mitochondrial structure and functioning

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

Identification of a fission yeast dynamin-related protein involved in mitochondrial DNA maintenance.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012919

19 August 2018

1 reference

12 December 2020

Mitochondrial DNA. I. Intramitochondrial distribution and structural relations of single- and double-length circular DNA

1 reference

12 December 2020

Heterologous mitochondrial DNA recombination in human cells

1 reference

12 December 2020

OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis

1 reference

12 December 2020

Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances

1 reference

12 December 2020

Fission yeast Msp1 is a mitochondrial dynamin-related protein

1 reference

12 December 2020

Reversible optic neuropathy with OPA1 exon 5b mutation

1 reference

12 December 2020

Transmembrane segments of the dynamin Msp1p uncouple its functions in the control of mitochondrial morphology and genome maintenance

1 reference

12 December 2020

Identifiers

DOI

10.1101/GR.108696.110

1 reference

3 October 2017

1 reference

3 October 2017

1 reference