(Q41560743)

3 October 2017

title

The deubiquitinating enzyme CYLD regulates the differentiation and maturation of thymic medullary epithelial cells (English)

1 reference

3 October 2017

3

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Nadine Hövelmeyer

2

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Ari Waisman

8

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author name string

Sonja Reissig

1

1 reference

3 October 2017

Nadine Hövelmeyer

2

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3 October 2017

Yilang Tang

3

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3 October 2017

Debra Weih

4

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3 October 2017

Alexey Nikolaev

5

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3 October 2017

Marc Riemann

6

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3 October 2017

Falk Weih

7

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3 October 2017

Ari Waisman

8

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3 October 2017

publication date

20 January 2015

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Immunology & Cell Biology

3 October 2017

published in

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3 October 2017

volume

93

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3 October 2017

issue

6

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3 October 2017

page(s)

558-566

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Thymic epithelial cells: working class heroes for T cell development and repertoire selection

3 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

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Promiscuous gene expression and central T-cell tolerance: more than meets the eye.

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Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes

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Self-representation in the thymus: an extended view

21 January 2018

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T cell tolerance to a neo-self antigen expressed by thymic epithelial cells: the soluble form is more effective than the membrane-bound form

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2014.122

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

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1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Expression of relB is required for the development of thymic medulla and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Deubiquitylation and regulation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Regulation of T cell development by the deubiquitinating enzyme CYLD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Naturally occurring short splice variant of CYLD positively regulates dendritic cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

The tumor suppressor CYLD controls the function of murine regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Generating intrathymic microenvironments to establish T-cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Projection of an immunological self shadow within the thymus by the aire protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Growth of epithelial cells in the thymic medulla is under the control of mature T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Dependence of self-tolerance on TRAF6-directed development of thymic stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Central tolerance: good but imperfect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Control of lymphocyte development by nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Thymic overexpression of CD40 ligand disrupts normal thymic epithelial organization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Analysis of thymic stromal cell populations using flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2014.122

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

21 January 2018

1 reference

12 December 2020

Aire and Foxp3 expression in a particular microenvironment for T cell differentiation

1 reference

12 December 2020

Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironment

1 reference

12 December 2020

In Vivo Treatment of Class II MHC-Deficient Mice with Anti-TCR Antibody Restores the Generation of Circulating CD4 T Cells and Optimal Architecture of Thymic Medulla

1 reference

12 December 2020

Identifiers

DOI

10.1038/ICB.2014.122

1 reference

3 October 2017

1 reference