(Q41564414)

3 October 2017

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title

Apoptosis: molecular mechanisms and implications for cancer chemotherapy (English)

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3 October 2017

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Guchelaar HJ

1

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3 October 2017

Vermes A

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2

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3 October 2017

Vermes I

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3

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3 October 2017

Haanen C

series ordinal

4

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3 October 2017

language of work or name

English

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publication date

1 June 1997

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International Journal of Clinical Pharmacy

3 October 2017

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3 October 2017

19

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3 October 2017

119-125

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3 October 2017

3

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Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival

3 October 2017

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12 December 2020

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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12 December 2020

Prognostic significance of p53 overexpression in primary breast cancer; a novel luminometric immunoassay applicable on steroid receptor cytosols

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12 December 2020

Regulation of lymphocyte survival by the bcl-2 gene family

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12 December 2020

Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism

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12 December 2020

Apoptotic neutrophils are phagocytosed by fibroblasts with participation of the fibroblast vitronectin receptor and involvement of a mannose/fucose-specific lectin

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12 December 2020

ICE-like proteases in apoptosis

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12 December 2020

Calcium-activated DNA fragmentation kills immature thymocytes

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12 December 2020

Apoptosis induction with three nucleoside analogs on freshly isolated B-chronic lymphocytic leukemia cells

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12 December 2020

Cancer progression and p53.

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12 December 2020

Mutant p53 protein associated with chemosensitivity in breast cancer specimens.

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12 December 2020

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

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12 December 2020

Ceramide: an intracellular signal for apoptosis

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12 December 2020

DNA fragmentation in targets of CTL: an example of programmed cell death in the immune system

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12 December 2020

Increasing the susceptibility of the rat 208F fibroblast cell line to radiation-induced apoptosis does not alter its clonogenic survival dose-response

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12 December 2020

Clinical implications of the p53 tumor-suppressor gene

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12 December 2020

Life, death, and the pursuit of apoptosis.

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12 December 2020

Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis

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12 December 2020

Apoptosis in murine tumors treated with chemotherapy agents

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12 December 2020

Ultrastructural observations on cell death by apoptosis in the ?resting? human breast

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12 December 2020

Apoptosis and a re-investigation of the biologic basis for cancer therapy

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12 December 2020

Cell nucleus and DNA fragmentation are not required for apoptosis

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12 December 2020

Probing the molecular program of apoptosis by cancer chemopreventive agents.

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12 December 2020

Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.

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12 December 2020

Ceramide: an endogenous regulator of apoptosis and growth suppression.

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12 December 2020

Cell-death by apoptosis following anticancer drug-treatment in-vitro.

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12 December 2020

p53 status and the efficacy of cancer therapy in vivo

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12 December 2020

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells

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12 December 2020

Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia

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12 December 2020

Apoptosis in cancer therapy: crossing the threshold

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12 December 2020

The p53 tumour suppressor gene

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12 December 2020

Apoptosis and cancer: the failure of controls on cell death and cell survival.

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12 December 2020

Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage

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12 December 2020

Apoptosis, cancer and the p53 tumour suppressor gene

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12 December 2020

Apoptosis and disease.

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12 December 2020

Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis.

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12 December 2020

Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma

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12 December 2020

Induction of DNA strand breaks associated with apoptosis during treatment of leukemias.

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12 December 2020

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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12 December 2020

The bcl-2 gene family

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12 December 2020

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

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12 December 2020

Apoptosis is inversely related to necrosis and determines net growth in tumors bearing constitutively expressed myc, ras, and HPV oncogenes

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12 December 2020

Control of apoptosis by the cellular ATP level

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12 December 2020

Cancer. p53, guardian of the genome

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12 December 2020

Programmed cell death and Bcl-2 protection in the absence of a nucleus

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12 December 2020

Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage-specific monoclonal antibody

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12 December 2020

Mitochondrial DNA is not fragmented during apoptosis

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12 December 2020

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages

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12 December 2020

The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

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12 December 2020

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

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12 December 2020

Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats.

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12 December 2020

Mechanisms and Functions of Cell Death

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12 December 2020

The killer and the executioner: how apoptosis controls malignancy.

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12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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12 December 2020

The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining.

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12 December 2020

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

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12 December 2020

Extracellular ATP as a trigger for apoptosis or programmed cell death

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12 December 2020

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death

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12 December 2020

Prognostic value of bcl-2 expression in invasive breast cancer

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12 December 2020

Protease activation during apoptosis: death by a thousand cuts?

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12 December 2020

Induction of apoptosis in murine tumors by cyclophosphamide

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12 December 2020

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12 December 2020

p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs

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12 December 2020

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

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12 December 2020

Apoptosis in the pathogenesis and treatment of disease

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12 December 2020

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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12 December 2020

Bcl-2 and the regulation of programmed cell death

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12 December 2020

Shrinkage necrosis: a distinct mode of cellular death.

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12 December 2020

Programmed cell death (apoptosis) and response to anti-cancer drugs.

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12 December 2020

Ceramide: a stress signal and mediator of growth suppression and apoptosis.

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12 December 2020

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

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12 December 2020

Apoptosis: programmed cell death in health and disease

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12 December 2020

Apoptosis induced by anticancer drugs

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12 December 2020

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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12 December 2020

Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene

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12 December 2020

Drug-target interactions: only the first step in the commitment to a programmed cell death?

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12 December 2020

Bcl-2 initiates a new category of oncogenes: regulators of cell death

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12 December 2020

Apoptosis and chemotherapy resistance

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12 December 2020

Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note.

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12 December 2020

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor

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12 December 2020

Expression and prognostic significance of Bcl-2 in ovarian tumours

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12 December 2020

The biochemistry of cell death by apoptosis

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12 December 2020

Apoptosis and therapy of malignant diseases of the hematopoietic system

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12 December 2020

Fludarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event

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12 December 2020

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

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12 December 2020

Expression of Bax in relation to Bcl-2 and other predictive parameters in breast cancer

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12 December 2020

Differential sensitivity to the induction of apoptosis by cisplatin in proliferating and quiescent immature rat thymocytes is independent of the levels of drug accumulation and DNA adduct formation.

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12 December 2020

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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12 December 2020

Apoptosis. Biochemical events and relevance to cancer chemotherapy

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12 December 2020

Phagocyte recognition of cells undergoing apoptosis

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12 December 2020

Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells

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12 December 2020

Identifiers

DOI

10.1023/A:1008654316572

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3 October 2017

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