(Q41572745)

4 October 2017

1 reference

title

Engineering novel proteins by transfer of active sites to natural scaffolds (English)

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4 October 2017

Vita C

1

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4 October 2017

1 August 1997

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Current Opinion in Biotechnology

4 October 2017

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4 October 2017

8

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4 October 2017

429-434

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4 October 2017

4

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Changing the binding specificity of a repressor by redesigning an alpha-helix

4 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Replacing the complementarity-determining regions in a human antibody with those from a mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Converting trypsin to chymotrypsin: the role of surface loops

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Attempts to convert chymotrypsin to trypsin

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Designing subtilisin BPN' to cleave substrates containing dibasic residues

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Furilisin: a variant of subtilisin BPN' engineered for cleaving tribasic substrates.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Structural differences between wild-type NADP-dependent glutathione reductase from Escherichia coli and a redesigned NAD-dependent mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Creation of an NADP-dependent pyruvate dehydrogenase multienzyme complex by protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Redesigning secondary structure to invert coenzyme specificity in isopropylmalate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Phage display: protein engineering by directed evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Engineering human prolactin to bind to the human growth hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

A covalent angiogenin/ribonuclease hybrid with a fourth disulfide bond generated by regional mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Replacing a Surface Loop Endows Ribonuclease A with Angiogenic Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Engineering of fibroblast growth factor: alteration of receptor binding specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Immune response to cholera toxin epitope inserted in Salmonella flagellin.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Fimbriae of Bacteroides nodosus: protein engineering of the structural subunit for the production of an exogenous peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

A genetic system to elicit and monitor antipeptide antibodies without peptide synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Antigenized antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Functional analysis and modeling of a conformationally constrained Arg-Gly-Asp sequence inserted into human lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Structure of a conformationally constrained Arg-Gly-Asp sequence inserted into human lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Strong inhibition of fibrinogen binding to platelet receptor alpha IIb beta 3 by RGD sequences installed into a presentation scaffold.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

A paradigm for drug discovery using a conformation from the crystal structure of a presentation scaffold

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Transfer of a beta-turn structure to a new protein context

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Modularity of protein function: chimeric interleukin 1 beta s containing specific protease inhibitor loops retain function of both molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Changing the structural context of a functional beta-hairpin. Synthesis and characterization of a chimera containing the curaremimetic loop of a snake toxin in the scorpion alpha/beta scaffold

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Scorpion toxins as natural scaffolds for protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Transfer of a beta-hairpin from the functional site of snake curaremimetic toxins to the alpha/beta scaffold of scorpion toxins: three-dimensional solution structure of the chimeric protein

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

Protein loop grafting to construct a variant of tissue-type plasminogen activator that binds platelet integrin alpha IIb beta 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2897%2980064-X

7 January 2021

10.1016/S0958-1669(97)80064-X

Identifiers

DOI

1 reference

4 October 2017

1 reference

PubMed ID

9265721