(Q41579896)

English

EO9: a novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models

scientific article published on January 1993

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scholarly article

1 reference

Europe PubMed Central

4 October 2017

EO9: a novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models (English)

1 reference

Europe PubMed Central

4 October 2017

author name string

Hendriks HR

1

1 reference

Europe PubMed Central

4 October 2017

Pizao PE

2

1 reference

Europe PubMed Central

4 October 2017

Berger DP

3

1 reference

Europe PubMed Central

4 October 2017

Kooistra KL

4

1 reference

Europe PubMed Central

4 October 2017

Bibby MC

5

1 reference

Europe PubMed Central

4 October 2017

Boven E

6

1 reference

Europe PubMed Central

4 October 2017

Dreef-van der Meulen HC

7

1 reference

Europe PubMed Central

4 October 2017

Henrar RE

8

1 reference

Europe PubMed Central

4 October 2017

Fiebig HH

9

1 reference

Europe PubMed Central

4 October 2017

Double JA

10

1 reference

Europe PubMed Central

4 October 2017

publication date

1 January 1993

1 reference

Europe PubMed Central

4 October 2017

European Journal of Cancer

1 reference

Europe PubMed Central

4 October 2017

29A

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Europe PubMed Central

4 October 2017

6

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Europe PubMed Central

4 October 2017

897-906

1 reference

Europe PubMed Central

4 October 2017

DT-diaphorase: questionable role in mitomycin C resistance, but a target for novel bioreductive drugs?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The Role of NAD(P)H: Quinone Reductase (EC 1.6.99.2, DT-Diaphorase) in the Reductive Bioactivation of the Novel Indoloquinone Antitumor Agent E09

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro activity of the novel indoloquinone EO-9 and the influence of pH on cytotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

New colorimetric cytotoxicity assay for anticancer-drug screening

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Colony assay with human tumor xenografts, murine tumors and human bone marrow. Potential for anticancer drug development.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The clonogenic assay with human tumor xenografts: evaluation, predictive value and application for drug screening.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Preclinical phase II study of ifosfamide in human tumour xenografts in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Therapeutic index: a vital component in selection of anticancer agents for clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of site on the chemosensitivity of transplantable murine colon tumours to flavone acetic acid (LM975, NSC 347512).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

CGP 6809--a new nitrosoureido-sugar derivative with activity in human tumor xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

General guidelines for the preclinical toxicology of new cytotoxic anticancer agents in Europe. Joint Steering Committee of the European Organization for Research and Treatment of Cancer (EORTC) and the Cancer Research Campaign (CRC)

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitomycin antitumour agents: a review of their physico-chemical and analytical properties and stability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-activity relationships for DT-diaphorase reduction of hypoxic cell directed agents: indoloquinones and diaziridinyl benzoquinones

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

DT-diaphorase activity correlates with sensitivity to the indoloquinone EO9 in mouse and human colon carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The sensitivity of human tumour cells to quinone bioreductive drugs: what role for DT-diaphorase?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitomycin C is not metabolized by but is an inhibitor of human kidney NAD(P)H: (quinone-acceptor)oxidoreductase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro and in vivo evaluation of the indoloquinone EO-9 (NSC 382 459) against human small cell carcinoma of the lung

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2805%2980434-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0959-8049(05)80434-4

1 reference

Europe PubMed Central

4 October 2017

1 reference

Europe PubMed Central

4 October 2017

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