(Q41594006)

4 October 2017

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title

Peptide-MHC complexes assembled following multiple pathways: an opportunity for the design of vaccines and therapeutic molecules (English)

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4 October 2017

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Corradin G

1

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4 October 2017

Demotz S

series ordinal

2

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4 October 2017

publication date

1 May 1997

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4 October 2017

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4 October 2017

volume

54

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4 October 2017

issue

2

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4 October 2017

page(s)

137-147

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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

4 October 2017

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HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

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Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein

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A new foreign policy: MHC class I molecules monitor the outside world

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Hepatitis B virus small surface antigen particles are processed in a novel endosomal pathway for major histocompatibility complex class I-restricted epitope presentation

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Antigen processing mutant T2 cells present viral antigen restricted through H-2Kb

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7 January 2021

MHC class II restricted antigen presentation

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7 January 2021

Assembly, transport, and function of MHC class II molecules

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HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells

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Mice lacking the MHC class II-associated invariant chain

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MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

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How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway

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7 January 2021

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

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7 January 2021

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

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7 January 2021

DR alpha beta dimers released from complexes with invariant chain fail to stimulate alloreactive T cell clones

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7 January 2021

T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates

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7 January 2021

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CL

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7 January 2021

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

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7 January 2021

Evidence for invariant chain 85-101 (CLIP) binding in the antigen binding site of MHC class II molecules

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7 January 2021

Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II molecules

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7 January 2021

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

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7 January 2021

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

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7 January 2021

Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant

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7 January 2021

HLA-DM: an in vivo facilitator of MHC class II peptide loading

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7 January 2021

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

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7 January 2021

How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

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7 January 2021

Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

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7 January 2021

Detection of functional class II-associated antigen: role of a low density endosomal compartment in antigen processing

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7 January 2021

Antigen-processing organelles from DRB1*1101 and DRB1*1104 B cell lines display a differential degradation activity

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7 January 2021

Dominance and crypticity of T cell antigenic determinants

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7 January 2021

Characterization of peptides bound to extracellular and intracellular HLA-DR1 molecules

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7 January 2021

Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules

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7 January 2021

Cell type-specific processing of the I-Ed-restricted hen egg lysozyme determinant 107-116.

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7 January 2021

Intracellular class II HLA antigens are accessible to transferrin-neuraminidase conjugates internalized by receptor-mediated endocytosis

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7 January 2021

Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

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7 January 2021

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7 January 2021

Intracellular assembly and transport of endogenous peptide-MHC class II complexes

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7 January 2021

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7 January 2021

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

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7 January 2021

Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments

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7 January 2021

Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface

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7 January 2021

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

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7 January 2021

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

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7 January 2021

Antigen presentation mediated by recycling of surface HLA-DR molecules.

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7 January 2021

Processing of DR1-restricted determinants from the fusion protein of measles virus following two distinct pathways

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7 January 2021

HLA-DM is localized to conventional and unconventional MHC class II-containing endocytic compartments.

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7 January 2021

Irreversible association of peptides with class II MHC molecules in living cells.

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7 January 2021

Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell

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7 January 2021

Early events in the assembly of major histocompatibility complex class II heterotrimers from their free subunits

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7 January 2021

Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

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7 January 2021

Assembly and peptide binding of major histocompatibility complex class II heterodimers in an in vitro translation system

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7 January 2021

Processing of a viral glycoprotein in the endoplasmic reticulum for class II presentation

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7 January 2021

Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak

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7 January 2021

Autophagy and related mechanisms of lysosome-mediated protein degradation

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7 January 2021

A novel and simple procedure for determining T cell epitopes in protein antigens

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7 January 2021

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells.

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7 January 2021

A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

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7 January 2021

The carrier effect in the secondary response to hapten-protein conjugates. I. Measurement of the effect with transferred cells and objections to the local environment hypothesis.

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7 January 2021

Carrier-priming leads to hapten-specific suppression.

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7 January 2021

Use of Prior Vaccinations for the Development of New Vaccines

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7 January 2021

Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system

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7 January 2021

Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria

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7 January 2021

Lack of H-2 restriction of the Plasmodium falciparum (NANP) sequence as multiple antigen peptide

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7 January 2021

Antigenicity and immunogenicity of multiple antigen peptides (MAP) containing P. vivax CS epitopes in Aotus monkeys

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7 January 2021

Identification of two promiscuous T cell epitopes from tetanus toxin

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7 January 2021

Recombinant fusion peptides containing single or multiple repeats of a ubiquitous T-helper epitope are highly immunogenic

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7 January 2021

Immunogenicity and in vivo efficacy of recombinant Plasmodium falciparum merozoite surface protein-1 in Aotus monkeys.

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7 January 2021

T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides

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7 January 2021

Induction of a cytotoxic T cell response by co-injection of a T helper peptide and a cytotoxic T lymphocyte peptide in incomplete Freund's adjuvant (IFA): further enhancement by pre-injection of IFA alone

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7 January 2021

CD8+ T-cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: evidence that localization of peptide-specific CTLs is crucial for protection against malaria

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7 January 2021

Identification of HIV protein-derived cytotoxic T lymphocyte (CTL) epitopes for their possible use as synthetic vaccine

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7 January 2021

Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans

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7 January 2021

Peptide-antibody conjugates for tumour therapy: a MHC-class-II-restricted tetanus toxin peptide coupled to an anti-Ig light chain antibody can induce cytotoxic lysis of a human B-cell lymphoma by specific CD4 T cells

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7 January 2021

10.1016/S0198-8859(97)00080-3

Identifiers

DOI

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4 October 2017

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