(Q41637569)

5 October 2017

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title

Principles and methods of evolutionary biotechnology (English)

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5 October 2017

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Koltermann A

1

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5 October 2017

Kettling U

series ordinal

2

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5 October 2017

publication date

1 June 1997

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5 October 2017

published in

Biophysical Chemistry

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5 October 2017

volume

66

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5 October 2017

issue

2-3

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5 October 2017

page(s)

159-177

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Selforganization of matter and the evolution of biological macromolecules

5 October 2017

cites work

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7 January 2021

The Molecular Quasi-Species

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7 January 2021

In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide.

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7 January 2021

The hypercycle. A principle of natural self-organization. Part A: Emergence of the hypercycle

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7 January 2021

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7 January 2021

The origin of genetic information: viruses as models

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7 January 2021

How to search for RNA structures. Theoretical concepts in evolutionary biotechnology

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7 January 2021

RNA based evolutionary optimization

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7 January 2021

Crystal structure of a catalytic antibody with a serine protease active site

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7 January 2021

Randomization of genes by PCR mutagenesis

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7 January 2021

Cassette mutagenesis: an efficient method for generation of multiple mutations at defined sites

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7 January 2021

Selection of new biological activities from random nucleotide sequences: evolutionary and practical considerations

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7 January 2021

Combinatorial libraries by cassette mutagenesis

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7 January 2021

Kinetics of RNA replication.

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7 January 2021

Oligonucleotides as research, diagnostic, and therapeutic agents

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

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7 January 2021

Comparison of self-sustained sequence-replication reaction systems

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7 January 2021

The Mutant Distribution of an RNA Species Replicated by Qβ Replicase

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7 January 2021

Structure-function relationships of hammerhead ribozymes: from understanding to applications.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

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https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

In vitro selection of RNA molecules that bind specific ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Diversity of oligonucleotide functions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

All you wanted to know about SELEX.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

RNA Selection: Aptamers achieve the desired recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Microsatellite 'evolution': directionality or bias?

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

A DNA aptamer that binds adenosine and ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

In vitro selection of RNA aptamers specific for cyanocobalamin

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

RNA aptamers that bind flavin and nicotinamide redox cofactors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

The tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

High-affinity RNA ligands to human alpha-thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of tetrahymena

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Biological catalysis by RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Origin of life: The RNA world

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Evolutionary optimization of the catalytic properties of a DNA-cleaving ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

In vitro evolution of new ribozymes with polynucleotide kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

An RNA motif that binds ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Kinetic and Thermodynamic Characterization of the Reaction Catalyzed by a Polynucleotide Kinase Ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

1 reference

7 January 2021

Selective chemical catalysis by an antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Expanding the scope of RNA catalysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

A self-replicating peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Peptide display on filamentous phage capsids. A new powerful tool to study protein-ligand interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Filamentous phage display of oligopeptide libraries.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Selection of proteins and peptides from libraries displayed on filamentous bacteriophage

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Phage antibodies: filamentous phage displaying antibody variable domains

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Making antibodies by phage display technology

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Characterization of the Neisseria Iga beta-core. The essential unit for outer membrane targeting and extracellular protein secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Practical applications of engineering gram-negative bacterial cell surfaces

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

The expression of recombinant proteins on the external surface of Escherichia coli. Biotechnological applications.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Yeast alpha mating factor structure-activity relationship derived from genetically selected peptide agonists and antagonists of Ste2p

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Clonal Selection and Amplification of Phage Displayed Antibodies by Linking Antigen Recognition and Phage Replication

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Direct interaction rescue, a novel filamentous phage technique to study protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Co-selection of cognate antibody-antigen pairs by selectively-infective phages.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Random peptide libraries: a source of specific protein binding molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

An M13 phage library displaying random 38-amino-acid peptides as a source of novel sequences with affinity to selected targets

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Screening of cyclic peptide phage libraries identifies ligands that bind streptavidin with high affinities

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Binding to protein targets of peptidic leads discovered by phage display: crystal structures of streptavidin-bound linear and cyclic peptide ligands containing the HPQ sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Directed evolution of a type I antifreeze protein expressed in Escherichia coli with sodium chloride as selective pressure and its effect on antifreeze tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Improved green fluorescent protein by molecular evolution using DNA shuffling

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

FACS-optimized mutants of the green fluorescent protein (GFP)

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Engineering nitrile hydratase activity into a cysteine protease by a single mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Natural protein proteinase inhibitors and their interaction with proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Selection of beta-lactamase on filamentous bacteriophage by catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Changes in the substrate specificities of an enzyme during directed evolution of new functions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Directed evolution of a second xylitol catabolic pathway in Klebsiella pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Enzyme evolution in Rhodobacter sphaeroides: selection of a mutant expressing a new galactitol dehydrogenase and biochemical characterization of the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Mutants generated by the insertion of random oligonucleotides into the active site of the beta-lactamase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Herpes thymidine kinase mutants with altered catalytic efficiencies obtained by random sequence selection.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Selection of new biologically active molecules from random nucleotide sequences.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Identification of important residues within the putative nucleoside binding site of HSV-1 thymidine kinase by random sequence selection: analysis of selected mutants in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Artificial mutants generated by the insertion of random oligonucleotides into the putative nucleoside binding site of the HSV-1 thymidine kinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

DNA polymerase beta can substitute for DNA polymerase I in the initiation of plasmid DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Overproduction of DnaE protein (alpha subunit of DNA polymerase III) restores viability in a conditionally inviable Escherichia coli strain deficient in DNA polymerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Unnatural nucleotide sequences in biopharmaceutics.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Tolerance of different proteins for amino acid diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Random mutagenesis of the substrate-binding site of a serine protease can generate enzymes with increased activities and altered primary specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Directed evolution of subtilisin E in Bacillus subtilis to enhance total activity in aqueous dimethylformamide

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Enzyme engineering for nonaqueous solvents: random mutagenesis to enhance activity of subtilisin E in polar organic media

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Enzyme engineering for nonaqueous solvents. II. Additive effects of mutations on the stability and activity of subtilisin E in polar organic media

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Improvement in the alkaline stability of subtilisin using an efficient random mutagenesis and screening procedure

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Proteases of enhanced stability: characterization of a thermostable variant of subtilisin

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

New developments in enzymatic peptide synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Engineering proteins for nonnatural environments.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Rapid evolution of a protein in vitro by DNA shuffling

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Molecular Architecture and Biological Reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

A stereospecific cyclization catalyzed by an antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Induction of an Antibody That Catalyzes the Hydrolysis of an Amide Bond

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Catalytic antibodies with lipase activity and R or S substrate selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

1 reference

7 January 2021

From molecular diversity to catalysis: lessons from the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

[34] Expression of functional antibody Fv and Fab fragments in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Antibodies from Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Making antibody fragments using phage display libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

The scope of antibody catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Immune recognition, antigen design, and catalytic antibody production

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Drug synthesis by genetically engineered microorganisms

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Substrate specificity of isopenicillin N synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Gamma-lactam analogues of beta-lactam antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

A macrolide 3-O-acyltransferase gene from the midecamycin-producing species Streptomyces mycarofaciens

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Production of a hybrid macrolide antibiotic in Streptomyces ambofaciens and Streptomyces lividans by introduction of a cloned carbomycin biosynthetic gene from Streptomyces thermotolerans

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Nucleotide sequences and heterologous expression of tcmG and tcmP, biosynthetic genes for tetracenomycin C in Streptomyces glaucescens

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Cloning and sequencing of a gene encoding carminomycin 4-O-methyltransferase from Streptomyces peucetius and its expression in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Overproduction of soluble trichodiene synthase from Fusarium sporotrichioides in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Generation of polyketide libraries via combinatorial biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Polyketide synthesis: prospects for hybrid antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Genetic engineering of Streptomyces to create hybrid antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Polyketide synthase gene manipulation: a structure-function approach in engineering novel antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Production of ‘hybrid’ antibiotics by genetic engineering

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Engineered biosynthesis of novel polyketides

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Engineered biosynthesis of a complete macrolactone in a heterologous host

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Expression of a functional fungal polyketide synthase in the bacterium Streptomyces coelicolor A3(2)

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Cellstat-a continuous culture system of a bacteriophage for the study of the mutation rate and the selection process of the DNA level

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Growth kinetics of a bacteriophage in continuous culture

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

High-throughput screening for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

Fluorescence correlation spectroscopy (FCS)--a highly sensitive method to analyze drug/target interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0301-4622%2897%2900063-X

7 January 2021

10.1016/S0301-4622(97)00063-X

Identifiers

DOI

1 reference

release_isiv4f4gtjfhvocdbre34ymdty

5 October 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/isiv4f4gtjfhvocdbre34ymdty

24 November 2022

mapped directly with Wikidata item

1 reference