(Q41652326)

6 October 2017

1 reference

title

Pathological mutations of nicotinic receptors and nicotine-based therapies for brain disorders (English)

1 reference

6 October 2017

Léna C

1

1 reference

PubMed ID

9384554

6 October 2017

Changeux JP

series ordinal

2

1 reference

6 October 2017

1 October 1997

1 reference

Current Opinion in Neurobiology

6 October 2017

1 reference

6 October 2017

7

1 reference

6 October 2017

674-682

1 reference

6 October 2017

5

1 reference

Neuronal nicotinic receptors: molecular organization and regulations

6 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotinic receptors in the development and modulation of CNS synapses.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

A model of the nicotinic receptor extracellular domain based on sequence identity and residue location

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Functional contributions of alpha5 subunit to neuronal acetylcholine receptor channels.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Assembly of human neuronal nicotinic receptor alpha5 subunits with alpha3, beta2, and beta4 subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Stable expression and pharmacological properties of the human alpha 7 nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Allosteric proteins after thirty years: the binding and state functions of the neuronal alpha 7 nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

The multiple phenotypes of allosteric receptor mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor epsilon subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Congenital myasthenic syndromes due to heteroallelic nonsense/missense mutations in the acetylcholine receptor epsilon subunit gene: identification and functional characterization of six new mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

End-plate acetylcholine receptor deficiency due to nonsense mutations in the epsilon subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

A beta-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Mutations in different functional domains of the human muscle acetylcholine receptor alpha subunit in patients with the slow-channel congenital myasthenic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Slow-channel myasthenic syndrome caused by enhanced activation, desensitization, and agonist binding affinity attributable to mutation in the M2 domain of the acetylcholine receptor alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Slow-channel transgenic mice: a model of postsynaptic organellar degeneration at the neuromuscular junction.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

An amino acid exchange in the second transmembrane segment of a neuronal nicotinic receptor causes partial epilepsy by altering its desensitization kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

An insertion mutation of the CHRNA4 gene in a family with autosomal dominant nocturnal frontal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Intravenous nicotine in Alzheimer's disease: a pilot study.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotinic autoreceptors mediating enhancement of acetylcholine release become operative in conditions of "impaired" cholinergic presynaptic function.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Potential treatment of Alzheimer disease using cholinergic channel activators (ChCAs) with cognitive enhancement, anxiolytic-like, and cytoprotective properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

(S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

The Wisconsin Card Sorting Test: Theoretical Analysis and Modeling in a Neuronal Network

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

The ascending neuromodulatory systems in learning by reinforcement: comparing computational conjectures with experimental findings

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

The biological, social and clinical bases of drug addiction: commentary and debate.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotine self-administration in animals and humans: similarities and differences

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Common neural substrates for the addictive properties of nicotine and cocaine.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Inhibition of monoamine oxidase B in the brains of smokers

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Cigarette smokers self-administer intravenous nicotine

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotine dependence, midbrain dopamine systems and psychiatric disorders.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotine-haloperidol interactions and cognitive performance in schizophrenics.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotine effects on adults with attention-deficit/hyperactivity disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotine may relieve symptoms of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

The short-term effect of nicotine chewing gum in patients with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotinic receptor function in schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Hippocampal synaptic transmission enhanced by low concentrations of nicotine.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

A leucine-to-phenylalanine substitution in the acetylcholine receptor ion channel in a family with the slow-channel syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0959-4388%2897%2980088-8

7 January 2021

10.1016/S0959-4388(97)80088-8

Identifiers

DOI

1 reference

6 October 2017

1 reference

PubMed ID

9384554