(Q41693676)

7 October 2017

Our cells get stressed too! Implications for human disease (English)

1 reference

7 October 2017

Michael B Kastan

1

1 reference

7 October 2017

29 May 2007

1 reference

Blood Cells, Molecules and Diseases

7 October 2017

1 reference

7 October 2017

39

1 reference

7 October 2017

2

1 reference

7 October 2017

148-150

1 reference

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome

7 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Initiating cellular stress responses

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

ATM: genome stability, neuronal development, and cancer cross paths

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

p53 down-regulation: a new molecular mechanism involved in ischaemic preconditioning

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1989115

Endogenous p53 Protects Vascular Smooth Muscle Cells From Apoptosis and Reduces Atherosclerosis in ApoE Knockout Mice

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17537652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17537652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BCMD.2007.04.002

1 reference

7 October 2017

1 reference

7 October 2017

1 reference

PMCID

1989115