(Q41700856)

7 October 2017

title

Presenilin-2 mutations modulate amplitude and kinetics of inositol 1, 4,5-trisphosphate-mediated calcium signals (English)

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7 October 2017

Leissring MA

1

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7 October 2017

Parker I

series ordinal

2

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7 October 2017

LaFerla FM

series ordinal

3

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7 October 2017

language of work or name

English

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publication date

1 November 1999

1 reference

Journal of Biological Chemistry

7 October 2017

published in

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7 October 2017

volume

274

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7 October 2017

issue

46

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7 October 2017

page(s)

32535-32538

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Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

7 October 2017

cites work

1 reference

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Candidate gene for the chromosome 1 familial Alzheimer's disease locus

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

21 January 2018

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Monogenic determinants of familial Alzheimer's disease: presenilin-2 mutations.

21 January 2018

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Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3

21 January 2018

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Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells

21 January 2018

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Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease

21 January 2018

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Calcium stores in cultured fibroblasts and their changes with Alzheimer's disease.

21 January 2018

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Abnormalities in Alzheimer's disease fibroblasts bearing the APP670/671 mutation.

21 January 2018

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Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families

21 January 2018

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Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes

21 January 2018

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Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

21 January 2018

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Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice

21 January 2018

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Calcium ionophore increases amyloid beta peptide production by cultured cells

21 January 2018

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Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons

21 January 2018

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The Calcium Rationale in Aging and Alzheimer's Disease

21 January 2018

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Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

21 January 2018

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Association of Sorcin With the Cardiac Ryanodine Receptor

21 January 2018

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Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels

21 January 2018

1 reference

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Caged inositol 1,4,5-trisphosphate for studying release of Ca2+ from intracellular stores

21 January 2018

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A continuum of InsP3-mediated elementary Ca2+ signalling events in Xenopus oocytes

21 January 2018

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Proteolytic fragments of the Alzheimer's disease associated presenilins-1 and -2 are phosphorylated in vivo by distinct cellular mechanisms

21 January 2018

1 reference

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Inositol trisphosphate-mediated Ca2+ influx into Xenopus oocytes triggers Ca2+ liberation from intracellular stores

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32535

Cloning of Xenopus presenilin-alpha and -beta cDNAs and their differential expression in oogenesis and embryogenesis

21 January 2018

1 reference

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The Xenopus IP3 receptor: structure, function, and localization in oocytes and eggs.

21 January 2018

1 reference

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Hypothesis on the regulation of cytosol calcium concentration and the aging brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32535

Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32535

Estimation of the Genetic Contribution of Presenilin-1 and -2 Mutations in a Population-Based Study of Presenile Alzheimer Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32535

Evidence That Intramolecular Associations between Presenilin Domains Are Obligatory for Endoproteolytic Processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.46.32535

21 January 2018

Identifiers

DOI

10.1074/JBC.274.46.32535

1 reference

7 October 2017

1 reference