(Q41701150)

7 October 2017

Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS). (English)

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7 October 2017

J M Dintaman

1

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PubMed ID

10554096

7 October 2017

J A Silverman

series ordinal

2

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7 October 2017

1 October 1999

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7 October 2017

Pharmaceutical Research

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7 October 2017

16

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7 October 2017

10

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7 October 2017

1550-1556

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Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

7 October 2017

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12 December 2020

Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells

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12 December 2020

Early steps of the P-glycoprotein expression in cell cultures studied with vital fluorochrome.

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12 December 2020

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

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12 December 2020

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

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12 December 2020

The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers

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12 December 2020

Multidrug resistance gene family and chemical carcinogens

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12 December 2020

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance

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12 December 2020

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals

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12 December 2020

The use of cultured epithelial and endothelial cells for drug transport and metabolism studies

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12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

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12 December 2020

Inhibition of intestinal P-glycoprotein and effects on etoposide absorption.

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12 December 2020

MDR1 gene expression in solid tumours

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12 December 2020

Epithelial secretion of vinblastine by human intestinal adenocarcinoma cell (HCT-8 and T84) layers expressing P-glycoprotein

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12 December 2020

Use of water-soluble liquid vitamin E to enhance cyclosporine absorption in children after liver transplant

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12 December 2020

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

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12 December 2020

Reversal of the multidrug resistance phenotype with cremophor EL, a common vehicle for water-insoluble vitamins and drugs

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12 December 2020

Measurement of cremophor EL following taxol: plasma levels sufficient to reverse drug exclusion mediated by the multidrug-resistant phenotype

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12 December 2020

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

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12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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12 December 2020

The multidrug transporter, a double-edged sword

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12 December 2020

Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters

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12 December 2020

Improvement of cyclosporin absorption in children after liver transplantation by means of water-soluble vitamin E

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12 December 2020

How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture.

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12 December 2020

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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12 December 2020

Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies

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12 December 2020

Functional characterization of the rat mdr1b encoded P-glycoprotein: not all inducing agents are substrates

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12 December 2020

Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes

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12 December 2020

Comparison of solutol HS 15, Cremophor EL and novel ethoxylated fatty acid surfactants as multidrug resistance modification agents

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12 December 2020

Active secretion and enterocytic drug metabolism barriers to drug absorption

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12 December 2020

Saquinavir, an HIV protease inhibitor, is transported by P-glycoprotein

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12 December 2020

MDR expression in normal tissues. Pharmacologic implications for the clinical use of P-glycoprotein inhibitors.

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12 December 2020

The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system

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12 December 2020

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

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12 December 2020

Effects of pluronic P85 unimers and micelles on drug permeability in polarized BBMEC and Caco-2 cells.

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12 December 2020

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

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12 December 2020

The biochemistry of P-glycoprotein-mediated multidrug resistance

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12 December 2020

Cremophor-EL enhances taxol efficacy in a multi-drug resistant C1300 neuroblastoma cell line.

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12 December 2020

Enhanced oral cyclosporine absorption with water-soluble vitamin E early after liver transplantation.

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12 December 2020

Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver

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12 December 2020

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

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12 December 2020

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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12 December 2020

Inhibition of the intestinal digoxin absorption and exsorption by quinidine

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12 December 2020

Differential effects of P-glycoprotein inhibitors on NIH3T3 cells transfected with wild-type (G185) or mutant (V185) multidrug transporters

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12 December 2020

Identifiers

DOI

10.1023/A:1015000503629

1 reference

7 October 2017

1 reference

PubMed ID

10554096