(Q41705437)

7 October 2017

title

Homology modeling and substrate binding study of human CYP2C9 enzyme (English)

1 reference

7 October 2017

Payne VA

1

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7 October 2017

Chang YT

series ordinal

2

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7 October 2017

Loew GH

series ordinal

3

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7 October 2017

language of work or name

English

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publication date

1 November 1999

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7 October 2017

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7 October 2017

volume

37

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7 October 2017

issue

2

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7 October 2017

page(s)

176-190

1 reference

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

7 October 2017

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Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes

21 January 2018

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Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes

21 January 2018

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Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

21 January 2018

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Identification of amino acid substitutions that confer a high affinity for sulfaphenazole binding and a high catalytic efficiency for warfarin metabolism to P450 2C19.

21 January 2018

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Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes

21 January 2018

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Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

21 January 2018

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Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution

21 January 2018

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Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

21 January 2018

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Modeling protein-substrate interactions in the heme domain of cytochrome P450(BM-3).

21 January 2018

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Structure of cytochrome P450eryF involved in erythromycin biosynthesis

21 January 2018

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21 January 2018

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21 January 2018

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Homology modeling and substrate binding study of human CYP4A11 enzyme

21 January 2018

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Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation

21 January 2018

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21 January 2018

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21 January 2018

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A hypervariable region of P450IIC5 confers progesterone 21-hydroxylase activity to P450IIC1.

21 January 2018

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The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.

21 January 2018

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A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli

21 January 2018

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Structure and function of cytochromes P450: a comparative analysis of three crystal structures.

21 January 2018

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Database algorithm for generating protein backbone and side-chain co-ordinates from a C alpha trace application to model building and detection of co-ordinate errors.

21 January 2018

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Conformational analysis of the backbone-dependent rotamer preferences of protein sidechains

21 January 2018

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Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool

21 January 2018

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21 January 2018

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Determining atom-centered monopoles from molecular electrostatic potentials. The need for high sampling density in formamide conformational analysis

21 January 2018

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21 January 2018

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21 January 2018

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Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

21 January 2018

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Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes

21 January 2018

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Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

21 January 2018

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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

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Oxidation of Tienilic Acid by Human Yeast-Expressed Cytochromes P-450 2C8, 2C9, 2C18 and 2C19. Evidence that this Drug is A Mechanism-Based Inhibitor Specific for Cytochrome P-450 2C9

21 January 2018

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The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An Approach Using Designed Tienilic Acid Derivatives and Molecular Modeling

21 January 2018

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The Substrate Binding Site of Human Liver Cytochrome P450 2C9: An NMR Study†

21 January 2018

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Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

21 January 2018

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Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations

21 January 2018

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10.1002/(SICI)1097-0134(19991101)37:2<176::AID-PROT4>3.0.CO;2-8

21 January 2018

Identifiers

DOI

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7 October 2017

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