(Q41719113)

PubMed publication ID

26007168

8 October 2017

title

Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

Marco Agostino Deriu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

Andrea Danani

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

Jack Tuszyński

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

author name string

Ginevra Licandro

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

Alessio Prunotto

4

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13 May 2020

language of work or name

English

0 references

publication date

8 May 2015

1 reference

PubMed publication ID

8 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

issue

5

1 reference

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13 May 2020

page(s)

8316-8340

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 May 2020

copyright license

start time

8 May 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides

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Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells

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Innate sensing of self and non-self RNAs by Toll-like receptors

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TLR7 and TLR8 as targets in cancer therapy

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The application of Toll like receptors for cancer therapy

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Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans

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Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation

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Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes

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A point mutation in the amino terminus of TLR7 abolishes signaling without affecting ligand binding

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Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

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CL097, a TLR7/8 ligand, inhibits TLR-4--dependent activation of IRAK-M and BCL-3 expression.

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Toll-like receptor 7 agonist therapy with imidazoquinoline enhances cancer cell death and increases lymphocytic infiltration and proinflammatory cytokine production in established tumors of a renal cell carcinoma mouse model

21 January 2018

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Current and potential uses of imiquimod

21 January 2018

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

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Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

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Resiquimod, a topical drug for viral skin lesions and skin cancer.

21 January 2018

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The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines.

21 January 2018

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The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

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Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2

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21 January 2018

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Advances in Homology Protein Structure Modeling

21 January 2018

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Homology modeling of human Toll-like receptors TLR7, 8, and 9 ligand-binding domains

21 January 2018

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A leucine-rich repeat assembly approach for homology modeling of the human TLR5-10 and mouse TLR11-13 ectodomains

21 January 2018

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Toll-like receptor 7 agonists: chemical feature based pharmacophore identification and molecular docking studies

21 January 2018

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Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

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An Extended Hückel Theory. I. Hydrocarbons

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Development and testing of a general amber force field

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Comparison of simple potential functions for simulating liquid water

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Verification of protein structures: patterns of nonbonded atomic interactions

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Efficient detection of three-dimensional structural motifs in biological macromolecules by computer vision techniques

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21 January 2018

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Langevin dynamics of peptides: the frictional dependence of isomerization rates of N-acetylalanyl-N'-methylamide

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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

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21 January 2018

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Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Imiquimod: modes of action

21 January 2018

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12 December 2020

Molecular dynamics with coupling to an external bath

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The normal-mode entropy in the MM/GBSA method: effect of system truncation, buffer region, and dielectric constant

21 January 2018

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Combining innate immunity with radiation therapy for cancer treatment

21 January 2018

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12 December 2020

Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent

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12 December 2020

The generalized Born/volume integral implicit solvent model: estimation of the free energy of hydration using London dispersion instead of atomic surface area

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12 December 2020

The antiviral activity of Toll-like receptor 7 and 7/8 agonists

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12 December 2020

Dual or triple activation of TLR7, TLR8, and/or TLR9 by single-stranded oligoribonucleotides

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12 December 2020

Negative regulation of the type I interferon signaling pathway by synthetic Toll-like receptor 7 ligands

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12 December 2020

TLR7/8 agonists trigger immunostimulatory properties of human 6-sulfo LacNAc dendritic cells

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12 December 2020

Homology and molecular dynamics models of toll-like receptor 7 protein and its dimerization

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12 December 2020

Imiquimod in the treatment of breast cancer skin metastasis

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12 December 2020

10.3390/MOLECULES20058316

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json

13 May 2020

PubMed publication ID

26007168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272798&resulttype=core&format=json