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Ras versus cyclin-dependent kinase inhibitors
scientific article published on February 1998
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scholarly article
1 reference
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Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
review article
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Europe PubMed Central
title
Ras versus cyclin-dependent kinase inhibitors
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
author name string
Lloyd AC
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
publication date
1 February 1998
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Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
published in
Current Opinion in Genetics & Development
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stated in
Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
volume
8
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Europe PubMed Central
PubMed ID
9529604
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8 October 2017
page(s)
43-48
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stated in
Europe PubMed Central
PubMed ID
9529604
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8 October 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
cites work
ras genes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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Cooperation between oncogenes
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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Cooperating oncogenes converge to regulate cyclin/cdk complexes.
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reference URL
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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
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Proliferative lifespan checkpoints: cell-type specificity and influence on tumour biology
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7 January 2021
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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
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p53: puzzle and paradigm
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Role of the INK4a locus in tumor suppression and cell mortality.
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Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.
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Lessons from hereditary colorectal cancer
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7 January 2021
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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
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7 January 2021
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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
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7 January 2021
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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
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7 January 2021
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Radiation-induced cell cycle arrest compromised by p21 deficiency
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7 January 2021
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The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.
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High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.
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7 January 2021
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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Genetic determinants of p53-induced apoptosis and growth arrest
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Inhibition of ras-induced proliferation and cellular transformation by p16INK4.
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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inferred from DOI database lookup
Regulation of the cell cycle by viral oncoproteins.
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Crossref
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7 January 2021
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Binding and modulation of p53 by p300/CBP coactivators
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7 January 2021
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Synergistic activation of transcription by CBP and p53
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7 January 2021
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Recruitment of p300/CBP in p53-dependent signal pathways
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7 January 2021
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The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.
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7 January 2021
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Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein
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Crossref
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7 January 2021
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CDC25 phosphatases as potential human oncogenes
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Transformation of mammalian cells by constitutively active MAP kinase kinase
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7 January 2021
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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
1 reference
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Adhesion-dependency of serum-induced p42/p44 MAP kinase activation is released by retroviral oncogenes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Ectopic expression of cyclin D1 but not cyclin E induces anchorage-independent cell cycle progression
1 reference
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Cell cycle: routine role for Ras.
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
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Dependence of cyclin E-CDK2 kinase activity on cell anchorage.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Inactivation of the cyclin D-dependent kinase in the rat fibroblast cell line, 3Y1, induced by contact inhibition
1 reference
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
A link between cyclin A expression and adhesion-dependent cell cycle progression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.
1 reference
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https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Integrins and anoikis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980060-9
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7 January 2021
based on heuristic
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Identifiers
DOI
10.1016/S0959-437X(98)80060-9
1 reference
stated in
Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
PubMed ID
9529604
1 reference
stated in
Europe PubMed Central
PubMed ID
9529604
retrieved
8 October 2017
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