(Q41743808)

8 October 2017

title

The stereoselective distribution of halofantrine enantiomers within human, dog, and rat plasma lipoproteins (English)

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8 October 2017

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Brocks DR

1

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8 October 2017

Ramaswamy M

series ordinal

2

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8 October 2017

MacInnes AI

series ordinal

3

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8 October 2017

Wasan KM

series ordinal

4

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8 October 2017

language of work or name

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1 April 2000

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8 October 2017

published in

Pharmaceutical Research

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8 October 2017

volume

17

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8 October 2017

issue

4

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8 October 2017

page(s)

427-431

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A comparison of step-gradient and sequential density ultracentrifugation and the use of lipoprotein deficient plasma controls in determining the plasma lipoprotein distribution of lipid-associated nystatin and cyclosporine

8 October 2017

cites work

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12 December 2020

In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum

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12 December 2020

The antimalarial drug halofantrine is bound mainly to low and high density lipoproteins in human serum

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12 December 2020

Stereochemical aspects of pharmacotherapy

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12 December 2020

Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria.

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12 December 2020

X-ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity.

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12 December 2020

Clinical pharmacokinetics of halofantrine

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12 December 2020

Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state

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12 December 2020

Plasmodium falciparum: role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents

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12 December 2020

A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma

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12 December 2020

Physiological parameters in laboratory animals and humans

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12 December 2020

A physicochemical basis for the effect of food on the absolute oral bioavailability of halofantrine

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12 December 2020

Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients

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12 December 2020

Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid

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12 December 2020

Cardiac complications of halofantrine: a prospective study of 20 patients

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12 December 2020

Pharmacokinetics of halofantrine in the rat: stereoselectivity and interspecies comparisons

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12 December 2020

Effect of altered serum lipid concentrations on the IC50 of halofantrine against Plasmodium falciparum

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12 December 2020

Differences in the lipoprotein distribution of halofantrine are regulated by lipoprotein apolar lipid and protein concentration and lipid transfer protein I activity: In vitro studies in normolipidemic and dyslipidemic human plasmas

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12 December 2020

Halofantrine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic potential

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12 December 2020

Identifiers

DOI

10.1023/A:1007524919865

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8 October 2017

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