(Q947595)

DrugBank

image of molecular model or crystal lattice model

17 November 2015

Halofantrine.svg
512 × 535; 5 KB

0 references

Halofantrine - 3D - Stick Model.png
1,647 × 1,703; 248 KB

depicts

ball-and-stick model

0 references

mass

499.165655 dalton

1 reference

Halofantrine (English)

4 October 2016

chemical formula

C₂₆H₃₀Cl₂F₃NO

1 reference

Halofantrine (English)

4 October 2016

canonical SMILES

CCCCN(CCCC)CCC(C1=C2C=CC(=CC2=C3C=C(C=C(C3=C1)Cl)Cl)C(F)(F)F)O

1 reference

Halofantrine (English)

4 October 2016

defined daily dose

1.5 gram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=P01BX01

World Health Organisation international non-proprietary name

Halofantrine (English)

1 reference

Halofantrine (English)

medical condition treated

19 January 2016

Plasmodium falciparum malaria

1 reference

13 December 2016

Plasmodium vivax malaria

1 reference

Food and Drug Administration

13 December 2016

Plasmodium vivax malaria

start time

10 December 1993

approved by

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/Q2OS4303HZ

http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf

Plasmodium falciparum malaria

start time

24 July 1992

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/Q2OS4303HZ

http://www.accessdata.fda.gov/drugsatfda_docs/label/2002/20250s7s8lbl.pdf

significant drug interaction

bepridil

1 reference

High-priority drug–drug interactions for use in electronic health records

sevoflurane

1 reference

High-priority drug–drug interactions for use in electronic health records

amiodarone

1 reference

High-priority drug–drug interactions for use in electronic health records

anagrelide

1 reference

High-priority drug–drug interactions for use in electronic health records

arsenic trioxide

1 reference

High-priority drug–drug interactions for use in electronic health records

astemizole

1 reference

High-priority drug–drug interactions for use in electronic health records

azithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

chloroquine

1 reference

High-priority drug–drug interactions for use in electronic health records

chlorpromazine

1 reference

High-priority drug–drug interactions for use in electronic health records

cisapride

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-citalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

clarithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

cocaine

1 reference

High-priority drug–drug interactions for use in electronic health records

disopyramide

1 reference

High-priority drug–drug interactions for use in electronic health records

dofetilide

1 reference

High-priority drug–drug interactions for use in electronic health records

domperidone

1 reference

High-priority drug–drug interactions for use in electronic health records

dronedarone

1 reference

High-priority drug–drug interactions for use in electronic health records

droperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

erythromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

escitalopram

1 reference

High-priority drug–drug interactions for use in electronic health records

flecainide

1 reference

High-priority drug–drug interactions for use in electronic health records

haloperidol

1 reference

High-priority drug–drug interactions for use in electronic health records

ibutilide

1 reference

High-priority drug–drug interactions for use in electronic health records

mesoridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-methadone

2 references

High-priority drug–drug interactions for use in electronic health records

https://www.drugs.com/drug-interactions/methadone-index.html

moxifloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

ondansetron

1 reference

High-priority drug–drug interactions for use in electronic health records

pentamidine

1 reference

High-priority drug–drug interactions for use in electronic health records

pimozide

1 reference

High-priority drug–drug interactions for use in electronic health records

probucol

1 reference

High-priority drug–drug interactions for use in electronic health records

procainamide

1 reference

High-priority drug–drug interactions for use in electronic health records

quinidine

1 reference

High-priority drug–drug interactions for use in electronic health records

sotalol

1 reference

High-priority drug–drug interactions for use in electronic health records

sparfloxacin

1 reference

High-priority drug–drug interactions for use in electronic health records

(RS)-sulpiride

1 reference

High-priority drug–drug interactions for use in electronic health records

terfenadine

1 reference

High-priority drug–drug interactions for use in electronic health records

thioridazine

1 reference

High-priority drug–drug interactions for use in electronic health records

subject has role

antimalarial

1 reference

InChI=1S/C26H30Cl2F3NO/c1-3-5-10-32(11-6-4-2)12-9-25(33)23-16-22-21(14-18(27)15-24(22)28)20-13-17(26(29,30)31)7-8-19(20)23/h7-8,13-16,25,33H,3-6,9-12H2,1-2H3

Medical Subject Headings

15 March 2018

Halofantrine

0 references

Identifiers

InChI

1 reference

Halofantrine (English)

FOHHNHSLJDZUGQ-UHFFFAOYSA-N

4 October 2016

InChIKey

2 references

Halofantrine (English)

4 October 2016

ChEBI release 2020-09-01

2 references

Halofantrine (English)

FOHHNHSLJDZUGQ-UHFFFAOYSA-N

4 October 2016

InChIKey

8 April 2021

https://commonchemistry.cas.org/detail?cas_rn=69756-53-2

1 reference

Halofantrine (English)

4 October 2016

1 reference

Halofantrine (English)

4 October 2016

ChEBI ID

94392

mapping relation type

1 reference

3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthrenyl]-1-propanol (English)

4 October 2016

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

HALOFANTRINE (English)

4 October 2016

1 reference

1 reference

DSSTOX compound identifier

DTXCID403119

0 references

EC number

274-104-1

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.067.346

27 December 2018

ECHA Substance Infocard ID

Halofantrine (English)

quotation

CAS no.: 69756-53-2 (English)

100.067.346

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.067.346

27 December 2018

Halofantrine (English)

quotation

CAS no.: 69756-53-2 (English)

1 reference

Guide to Pharmacology Ligand ID

Halofantrine (English)

publication date

17 November 2015

10019

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

5 February 2021

1 reference

Medical Subject Headings

14 March 2018

1 reference

26 February 2018

1 reference

Halofantrine (English)

Human Metabolome Database ID

4 October 2016

HMDB0015349

1 reference

based on heuristic

inferred from InChIKey

1 reference

Halofantrine (English)

4 October 2016

1 reference