(Q41751967)

8 October 2017

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title

Localized delivery of proteins in the brain: can transport be customized? (English)

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8 October 2017

Haller MF

1

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PubMed ID

9563066

8 October 2017

Saltzman WM

series ordinal

2

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PubMed ID

9563066

8 October 2017

language of work or name

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1 March 1998

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8 October 2017

Pharmaceutical Research

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8 October 2017

15

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8 October 2017

3

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8 October 2017

377-385

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Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

8 October 2017

1 reference

12 December 2020

High-flow microinfusion: tissue penetration and pharmacodynamics.

1 reference

12 December 2020

Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies

1 reference

12 December 2020

Ion-selective microelectrodes and diffusion measurements as tools to explore the brain cell microenvironment

1 reference

12 December 2020

Engineering dynamics of growth factors and other therapeutic ligands

1 reference

12 December 2020

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

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12 December 2020

Two-photon molecular excitation provides intrinsic 3-dimensional resolution for laser-based microscopy and microphotochemistry

1 reference

12 December 2020

Drug "diffusion" within the brain.

1 reference

12 December 2020

Long distance pathways of diffusion for dextran along fibre bundles in brain. Relevance for volume transmission

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12 December 2020

Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface.

1 reference

12 December 2020

Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons

1 reference

12 December 2020

Interstitial transport of rabbit and sheep antibodies in normal and neoplastic tissues

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12 December 2020

Transport and elimination of recombinant human NGF during long-term delivery to the brain

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12 December 2020

Diffusional transport of macromolecules in developing nerve processes

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12 December 2020

Barriers to drug delivery in solid tumors

1 reference

12 December 2020

Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates

1 reference

12 December 2020

Extravascular diffusion in normal and neoplastic tissues

1 reference

12 December 2020

NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion

1 reference

12 December 2020

Brain interstitial volume fraction and tortuosity in anoxia. Evaluation of the ion-selective micro-electrode method.

1 reference

12 December 2020

Polymer conjugates. Pharmacokinetic considerations for design and development

1 reference

12 December 2020

Sucrose and inulin space measurements of cerebral cortex in four mammalian species

1 reference

12 December 2020

Quantitative Examination of Tissue Concentration Profiles Associated with Microdialysis

1 reference

12 December 2020

Implantation of polymer-encapsulated human nerve growth factor-secreting fibroblasts attenuates the behavioral and neuropathological consequences of quinolinic acid injections into rodent striatum

1 reference

12 December 2020

The use of magnetic resonance imaging to track controlled drug release and transport in the brain.

1 reference

12 December 2020

Enhanced survival and neuronal differentiation of adrenal chromaffin cells cografted into the striatum with NGF-producing fibroblasts

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12 December 2020

Internalization and excretion of epidermal growth factor-dextran-associated radioactivity in cultured human squamous-carcinoma cells

1 reference

12 December 2020

Treatment of adenosine deaminase deficiency with polyethylene glycol-modified adenosine deaminase

1 reference

12 December 2020

Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection

1 reference

12 December 2020

Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis.

1 reference

12 December 2020

Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat.

1 reference

12 December 2020

A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. The Tacrine Collaborative Study Group.

1 reference

12 December 2020

Receptor-mediated retrograde transport in CNS neurons after intraventricular administration of NGF and growth factors

1 reference

12 December 2020

Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum

1 reference

12 December 2020

Sustained Release of Nerve Growth Factor from Biodegradable Polymer Microspheres

1 reference

12 December 2020

Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain.

1 reference

12 December 2020

Macromolecules released from polymers: diffusion into unstirred fluids.

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12 December 2020

Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

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12 December 2020

Diffusion characteristics and extracellular volume fraction during normoxia and hypoxia in slices of rat neostriatum.

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12 December 2020

Visualization of slow axonal transport in vivo.

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12 December 2020

The use of the fluorescence photobleaching recovery technique to study the self-assembly of tubulin

1 reference

12 December 2020

Motor fluctuations in Parkinson's disease: pathogenetic and therapeutic studies

1 reference

12 December 2020

Fluorescence photobleaching with spatial Fourier analysis: measurement of diffusion in light-scattering media

1 reference

12 December 2020

Macromolecular permeability across the blood-nerve and blood-brain barriers

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12 December 2020

Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication.

1 reference

12 December 2020

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection

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12 December 2020

Measuring serotonin distribution in live cells with three-photon excitation

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12 December 2020

Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neurites after intraventricular administration of nerve growth factor

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12 December 2020

Clinical pharmacology of polyethylene glycol-L-asparaginase

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12 December 2020

In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain

1 reference

12 December 2020

Antibody diffusion in human cervical mucus

1 reference

12 December 2020

Multiphoton fluorescence excitation: new spectral windows for biological nonlinear microscopy.

1 reference

12 December 2020

Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion

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12 December 2020

The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

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12 December 2020

Mobility measurement by analysis of fluorescence photobleaching recovery kinetics

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12 December 2020

Hindered diffusion in agarose gels: test of effective medium model

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12 December 2020

Fate of receptor and ligand during endocytosis of asialoglycoproteins by isolated hepatocytes

1 reference

12 December 2020

Nerve growth factor infusions combined with fetal hippocampal grafts enhance reconstruction of the lesioned septohippocampal projection.

1 reference

12 December 2020

Endocytic Relay as a Potential Means for Enhancing Ligand Transport through Cellular Tissue Matrices: Analysis and Possible Implications for Drug Delivery

1 reference

12 December 2020

Autoradiographic study of [125I]epidermal growth factor-binding sites in the mesencephalon of control and parkinsonian brains post-mortem

1 reference

12 December 2020

Diffusion coefficient of fluorescein-labeled tubulin in the cytoplasm of embryonic cells of a sea urchin: video image analysis of fluorescence redistribution after photobleaching

1 reference

12 December 2020

Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants.

1 reference

12 December 2020

Nerve growth factor delivery and cell aggregation enhance choline acetyltransferase activity after neural transplantation.

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12 December 2020

Detection of dopamine overflow and diffusion with voltammetry in slices of rat brain.

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12 December 2020

Distribution of nerve growth factor following direct delivery to brain interstitium

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12 December 2020

Diffusion properties of brain tissue measured with electrode methods and prospects for optical analysis.

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12 December 2020

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

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12 December 2020

Albumin outflow into deep cervical lymph from different regions of rabbit brain.

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12 December 2020

Retrograde axonal transport of signal transduction proteins in rat sciatic nerve

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12 December 2020

Distribution of drugs following controlled delivery to the brain interstitium

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12 December 2020

Differential distribution of exogenous BDNF, NGF, and NT-3 in the brain corresponds to the relative abundance and distribution of high-affinity and low-affinity neurotrophin receptors

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12 December 2020

Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders

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12 December 2020

Antibodies for treating and preventing disease: the potential role of polymeric controlled release.

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12 December 2020

Dextran Retention in the Rat Brain Following Release from a Polymer Implant

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12 December 2020

Glucose diffusion coefficients determined from concentration profiles in EMT6 tumor spheroids incubated in radioactively labeled L-glucose.

1 reference

12 December 2020

Diffusion of albumins in rat cortical slices and relevance to volume transmission.

1 reference

12 December 2020

Epidermal growth factor exerts neuronotrophic effects on dopaminergic and GABAergic CNS neurons: Comparison with basic fibroblast growth factor

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12 December 2020

Covalent coupling of methotrexate to dextran enhances the penetration of cytotoxicity into a tissue-like matrix.

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12 December 2020

Diffusion of fluorescein-labelled molecules in suspensions of erythrocyte ghosts

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12 December 2020

Stabilization of nerve growth factor in controlled release polymers and in tissue.

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12 December 2020

Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group

1 reference

12 December 2020

Role of growth factors in degeneration and regeneration in the central nervous system; clinical experiences with NGF in Parkinson's and Alzheimer's diseases.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1011911912174

1 reference

8 October 2017

1 reference

PubMed ID

9563066