(Q41774263)

English

Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus.

scientific article published on 28 July 2011

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10 February 2020

Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus (English)

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10 February 2020

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10 February 2020

Yehezkel Ben-Ari

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10 February 2020

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28 July 2011

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10 February 2020

Frontiers in Cellular Neuroscience

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10 February 2020

Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.

1 reference

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6 June 2018

Robust tonic GABA currents can inhibit cell firing in mouse newborn neocortical pyramidal cells

1 reference

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6 June 2018

Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Temporal coding at the immature depolarizing GABAergic synapse.

1 reference

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6 June 2018

Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

In the developing rat hippocampus, endogenous activation of presynaptic kainate receptors reduces GABA release from mossy fiber terminals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

The interaction of the neuroprotective compounds riluzole and phenobarbital with AMPA-type glutamate receptors: a patch-clamp study

1 reference

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6 June 2018

Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

The impact of diazepam's discovery on the treatment and understanding of status epilepticus

1 reference

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6 June 2018

Cation-chloride cotransporters and neuronal function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Interictal high-frequency oscillations (80-500 Hz) are an indicator of seizure onset areas independent of spikes in the human epileptic brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Gamma-aminobutyric acid (GABA) and pentobarbital induce different conformational rearrangements in the GABA A receptor alpha1 and beta2 pre-M1 regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Structural mechanisms underlying benzodiazepine modulation of the GABA(A) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Subunit-specific trafficking of GABA(A) receptors during status epilepticus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Treatment of pediatric epilepsy: European expert opinion, 2007.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

GABA transient sets the susceptibility of mIPSCs to modulation by benzodiazepine receptor agonists in rat hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Seizure recurrence and developmental disabilities after neonatal seizures: outcomes are unrelated to use of phenobarbital prophylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Benzodiazepine receptor agonists affect both binding and gating of recombinant alpha1beta2gamma2 gamma-aminobutyric acid-A receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Novel anticonvulsant drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

The dark side of high-frequency oscillations in the developing brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

GABA regulates synaptic integration of newly generated neurons in the adult brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Mechanisms of action of antiepileptic drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Continuous pentobarbital infusion in children is associated with high rates of complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2L GABAA receptor currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

The neurobiology of antiepileptic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Mechanism of activity-dependent downregulation of the neuron-specific K-Cl cotransporter KCC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Cation-chloride co-transporters in neuronal communication, development and trauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

On the origin of interictal activity in human temporal lobe epilepsy in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Phenobarbitone, neonatal seizures, and video-EEG.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Anticonvulsants: aspects of their mechanisms of action

1 reference

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6 June 2018

Blockade of glutamate receptors and barbiturate anesthesia: increased sensitivity to pentobarbital-induced anesthesia despite reduced inhibition of AMPA receptors in GluR2 null mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Electrophysiologic analysis of a chronic seizure model after unilateral hippocampal KA injection

1 reference

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6 June 2018

Phenobarbital compared with phenytoin for the treatment of neonatal seizures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Antiepileptic drug-induced worsening of seizures in children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Antiepileptic drugs as a cause of worsening seizures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

A novel in vitro preparation: the intact hippocampal formation.

1 reference

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6 June 2018

The pilocarpine model of epilepsy in mice

1 reference

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6 June 2018

Amplitude fluctuations of dual-component EPSCs in hippocampal pyramidal cells: implications for long-term potentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Mechanisms of action of currently prescribed and newly developed antiepileptic drugs

1 reference

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6 June 2018

Pentobarbital: selective depression of excitatory postsynaptic potentials.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Differing actions of convulsant and nonconvulsant barbiturates: An electrophysiological study in the isolated spinal cord of the rat

1 reference

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6 June 2018

Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses.

1 reference

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6 June 2018

Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy

1 reference

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6 June 2018

Clinical and EEG response to anticonvulsants in neonatal seizures

1 reference

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6 June 2018

Comparison of the anticonvulsant efficacy of primidone and phenobarbital during chronic treatment of amygdala-kindled rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Giant synaptic potentials in immature rat CA3 hippocampal neurones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

Barbiturates decrease voltage-dependent calcium conductance of mouse neurons in dissociated cell culture

1 reference

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6 June 2018

Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

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Diazepam pretreatment reduces distant hippocampal damage induced by intra-amygdaloid injections of kainic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

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Pentobarbitone pharmacology of mammalian central neurones grown in tissue culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

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Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones

1 reference

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Enhancement of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: A common mode of anticonvulsant action

1 reference

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1 reference

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6 June 2018

Phenobarbitone modulation of postsynaptic GABA receptor function on cultured mammalian neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

6 June 2018

GABAergic hub neurons orchestrate synchrony in developing hippocampal networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Brief alteration of NMDA or GABAA receptor-mediated neurotransmission has long term effects on the developing cerebral cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Neonatal seizures: dilemmas in workup and management.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Neonatal seizures: multicenter variability in current treatment practices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Epileptogenic actions of GABA and fast oscillations in the developing hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Structural determinants of benzodiazepine allosteric regulation of GABA(A) receptor currents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Drug treatment of neonatal seizures by neonatologists and paediatric neurologists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

In vitro formation of a secondary epileptogenic mirror focus by interhippocampal propagation of seizures

1 reference

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18 August 2018

When midazolam fails

1 reference

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18 August 2018

Maturation of kainate-induced epileptiform activities in interconnected intact neonatal limbic structures in vitro.

1 reference

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18 August 2018

Comparison of the effects of convulsant and depressant barbiturate stereoisomers on AMPA-type glutamate receptors.

1 reference

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18 August 2018

Sites of volatile anesthetic action on kainate (Glutamate receptor 6) receptors.

1 reference

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18 August 2018

Anesthetics produce subunit-selective actions on glutamate receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3148783

18 August 2018

Sensitivity of AMPA receptors to pentobarbital.

1 reference

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18 August 2018

Changes in reliability of synaptic function as a mechanism for plasticity.

1 reference

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18 August 2018

Benzodiazepines modulate calcium spikes in young and adult hippocampal cells.

1 reference

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18 August 2018

Multiple actions of picomolar concentrations of flurazepam on the excitability of cultured mouse spinal neurons.

1 reference

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18 August 2018

Barbiturate reduction of calcium-dependent action potentials: Correlation with anesthetic action

1 reference

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18 August 2018

Transient expression of a novel type of GABA response in rat CA3 hippocampal neurones during development

1 reference

https://pubmed.ncbi.nlm.nih.gov/21847371

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular bases of barbiturate and phenytoin anticonvulsant drug action

1 reference

https://pubmed.ncbi.nlm.nih.gov/21847371

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/21847371

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FNCEL.2011.00016

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21847371%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21847371%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21847371%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

ResearchGate publication ID

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