(Q41792378)

10 October 2017

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. (English)

1 reference

Unc-51 like autophagy activating kinase 1

10 October 2017

0 references

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

2

1 reference

10 October 2017

Matteo Bordi

6

0 references

Pamela Bielli

Pamela Bielli

4

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Manuela Antonioli

Manuela Antonioli

3

0 references

Francesca Nazio

Francesca Nazio

1

0 references

Valentina Cianfanelli

Valentina Cianfanelli

5

0 references

Jörn Dengjel

Joern Dengjel

8

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Francesco Cecconi

Francesco Cecconi

11

0 references

Gian Maria Fimia

Gian Maria Fimia

10

0 references

Mauro Piacentini

9

Mauro Piacentini

1 reference

10 October 2017

7

Christine Gretzmeier

1 reference

10 October 2017

24 March 2013

1 reference

10 October 2017

1 reference

10 October 2017

15

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10 October 2017

406-416

1 reference

10 October 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/ncb2708

10 October 2017

0 references

cites work

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

1 reference

12 December 2020

Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons

1 reference

12 December 2020

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

1 reference

12 December 2020

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

1 reference

12 December 2020

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

1 reference

12 December 2020

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

1 reference

12 December 2020

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

1 reference

12 December 2020

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

1 reference

12 December 2020

Autophagy: renovation of cells and tissues

1 reference

12 December 2020

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

12 December 2020

Noncovalent dimerization of ubiquitin

1 reference

12 December 2020

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

12 December 2020

Nonproteolytic functions of ubiquitin in cell signaling

1 reference

12 December 2020

Atg101, a novel mammalian autophagy protein interacting with Atg13

1 reference

12 December 2020

An Atg13 protein-mediated self-association of the Atg1 protein kinase is important for the induction of autophagy

1 reference

12 December 2020

Distinct molecular mechanism for initiating TRAF6 signalling

1 reference

12 December 2020

Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1.

1 reference

12 December 2020

Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell death

1 reference

12 December 2020

Ambra1 regulates autophagy and development of the nervous system

1 reference

12 December 2020

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

1 reference

12 December 2020

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

1 reference

12 December 2020

Targeting the ubiquitin system in cancer therapy

1 reference

12 December 2020

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

1 reference

12 December 2020

The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

1 reference

12 December 2020

Network organization of the human autophagy system

1 reference

12 December 2020

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

1 reference

12 December 2020

A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons

1 reference

12 December 2020

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

1 reference

12 December 2020

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

1 reference

12 December 2020

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

1 reference

12 December 2020

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

1 reference

12 December 2020

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

1 reference

12 December 2020

Intrinsically unstructured proteins and their functions

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2708

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCB2708

1 reference

10 October 2017

1 reference

PubMed ID

23524951