(Q41813859)

English

Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance.

scientific article published on 22 May 2012

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scholarly article

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2 February 2020

Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance (English)

1 reference

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2 February 2020

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

3

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2 February 2020

author name string

John R Ussher

1

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2 February 2020

Clifford D L Folmes

2

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2 February 2020

Natasha Fillmore

4

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2 February 2020

Jagdip S Jaswal

5

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2 February 2020

Virgilio J Cadete

6

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2 February 2020

Donna L Beker

7

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2 February 2020

Victoria H Lam

8

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2 February 2020

Liyan Zhang

9

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2 February 2020

Gary D Lopaschuk

10

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2 February 2020

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22 May 2012

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2 February 2020

1 reference

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2 February 2020

7

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2 February 2020

5

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2 February 2020

e37703

1 reference

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2 February 2020

copyright license

Creative Commons Attribution 4.0 International

22 May 2012

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April 2022 Public Data File from Crossref

copyright status

0 references

Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo

1 reference

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6 June 2018

Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption

1 reference

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Myocardial fatty acid metabolism in health and disease

1 reference

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6 June 2018

Myocardium of type 2 diabetic and obese patients is characterized by alterations in sphingolipid metabolic enzymes but not by accumulation of ceramide.

1 reference

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6 June 2018

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase

1 reference

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6 June 2018

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

1 reference

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6 June 2018

Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion

1 reference

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6 June 2018

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

1 reference

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6 June 2018

The malonyl CoA axis as a potential target for treating ischaemic heart disease

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Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

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Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

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6 June 2018

Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats

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Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3.

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6 June 2018

Ceramides in insulin resistance and lipotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes

1 reference

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6 June 2018

Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

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The obesity epidemic, metabolic syndrome and future prevention strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

Impairment of glucose metabolism in hearts from rats treated with endotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

The worldwide obesity epidemic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

A novel mouse model of lipotoxic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

6 June 2018

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

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Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

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Increased CD36 expression in middle-aged mice contributes to obesity-related cardiac hypertrophy in the absence of cardiac dysfunction.

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Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle.

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Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358297

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Potential mechanisms and consequences of cardiac triacylglycerol accumulation in insulin-resistant rats

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Measurement of ceramide levels by the diacylglycerol kinase reaction and by high-performance liquid chromatography-fluorescence spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22629445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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inferred from PubMed ID database lookup

Protons in ischemia: where do they come from; where do they go to?

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https://pubmed.ncbi.nlm.nih.gov/22629445

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inferred from PubMed ID database lookup

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22629445

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/22629445

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inferred from PubMed ID database lookup

Fatty acids attenuate insulin regulation of 5'-AMP-activated protein kinase and insulin cardioprotection after ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22629445

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based on heuristic

inferred from PubMed ID database lookup

Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22629445

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based on heuristic

inferred from PubMed ID database lookup

Induction of cardiac uncoupling protein-2 expression and adenosine 5'-monophosphate-activated protein kinase phosphorylation during early states of diet-induced obesity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22629445

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0037703

1 reference

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2 February 2020

2012PLoSO...737703U

0 references

1 reference

Europe PubMed Central

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2 February 2020

1 reference

Europe PubMed Central

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2 February 2020

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