(Q41817691)

English

Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia

scientific article published on 12 March 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

12 October 2017

Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia (English)

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

frontotemporal dementia

1 reference

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inferred from title

Tara L Spires-Jones

object named as

Tara L Spires-Jones

1

0 references

author name string

Leora M Fox

2

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Anete Rozkalne

3

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Rose Pitstick

4

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

George A Carlson

5

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Aleksey G Kazantsev

6

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

language of work or name

1 reference

based on heuristic

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publication date

12 March 2012

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Frontiers in Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

3

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

42

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

A brain-permeable small molecule reduces neuronal cholesterol by inhibiting activity of sirtuin 2 deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Contemporary approaches to Alzheimer's disease and frontotemporal dementia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Tau pathophysiology in neurodegeneration: a tangled issue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Therapeutic role of sirtuins in neurodegenerative disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Sirtuins in mammals: insights into their biological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Molecular mechanisms mediating pathological plasticity in Huntington's disease and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Tau suppression in a neurodegenerative mouse model improves memory function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Calorie restriction--the SIR2 connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Frontal lobe atrophy due to a mutation in the cholesterol binding protein HE1/NPC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Structural correlates of cognition in dementia: quantification and assessment of synapse change.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

6 June 2018

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

18 August 2018

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

18 August 2018

Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

18 August 2018

Behavioural effects of dimethyl sulfoxide (DMSO): changes in sleep architecture in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298895

18 August 2018

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22416232

12 December 2020

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Identifiers

10.3389/FPHAR.2012.00042

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

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