(Q41817751)

English

The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase

scientific article published on July 16, 1997

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scholarly article

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Europe PubMed Central

PMC publication ID

12 October 2017

The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase (English)

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Europe PubMed Central

PMC publication ID

12 October 2017

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mitogen-activated protein kinase kinases

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

author name string

H. Ma

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

M. Gamper

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

C. Parent

3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

R. A. Firtel

4

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

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publication date

1 July 1997

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12 October 2017

16 July 1997

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9250676

10 November 2024

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https://europepmc.org/articles/pmc1170058?pdf=render

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

https://europepmc.org/articles/PMC1170058

online access status

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

https://europepmc.org/articles/PMC1170058?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250676

10 November 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1093%2Femboj%2F16.14.4317

1 reference

10.1093/EMBOJ/16.14.4317

https://api.crossref.org/works/10.1093/EMBOJ/16.14.4317

10 November 2024

https://onlinelibrary.wiley.com/doi/full/10.1093/emboj/16.14.4317

1 reference

10.1093/EMBOJ/16.14.4317

https://api.crossref.org/works/10.1093/EMBOJ/16.14.4317

10 November 2024

The EMBO Journal

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

16

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

14

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

4317-4332

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Complete sequence and transcript regulation of a cell adhesion protein from aggregating Dictyostelium cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Signaling through chemoattractant receptors in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Dual role of cAMP and involvement of both G-proteins and ras in regulation of ERK2 in Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Transduction of the chemotactic cAMP signal across the plasma membrane of Dictyostelium cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Yeast MEK-dependent signal transduction: response thresholds and parameters affecting fidelity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

A conserved kinase cascade for MAP kinase activation in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

The mitogen-activated protein kinase signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Phospholipase C in Dictyostelium discoideum. Cyclic AMP surface receptor and G-protein-regulated activity in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

A transformation vector for dictyostelium discoideum with a new selectable marker bsr.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

G protein-linked signaling pathways control the developmental program of Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Transformation of mammalian cells by constitutively active MAP kinase kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

A model for cAMP-mediated cGMP response in Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

MAP kinase pathways in yeast: for mating and more

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Chemoattractant and GTP gamma S-mediated stimulation of adenylyl cyclase in Dictyostelium requires translocation of CRAC to membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

cAMP-dependent protein kinase activity is essential for preaggregative gene expression in Dictyostelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Biochemical and biological analysis of Mek1 phosphorylation site mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

The proliferation of MAP kinase signaling pathways in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Regulation by protein-tyrosine phosphatase PTP2 is distinct from that by PTP1 during Dictyostelium growth and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Induction and modulation of cell-type-specific gene expression in Dictyostelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Microbiological assay of cyclic 3',5'-AMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

G-proteins in the signal-transduction pathways of Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Developmental regulation of Dictyostelium discoideum actin gene fusions carried on low-copy and high-copy transformation vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Chemotaxis in eukaryotic cells: a focus on leukocytes and Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: implications for cdc2+ protein structure and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Overproduction of the regulatory subunit of the cAMP-dependent protein kinase blocks the differentiation of Dictyostelium discoideum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

Adenylate cyclase assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

6 June 2018

The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by Ras and cAMP-dependent protein kinase (PKA) and mediates PKA function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

The role of the cyclic nucleotide phosphodiesterase of Dictyostelium discoideum during growth, aggregation, and morphogenesis: overexpression and localization studies with the separate promoters of the pde.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

Progression of an inductive signal activates sporulation in Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

Regulation of Dictyostelium early development genes in signal transduction mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170058

18 August 2018

Direct induction of dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple intracellular MAP kinase signaling cascades

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology in Dictyostelium: tools and applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of CRAC, a cytosolic regulator required for guanine nucleotide stimulation of adenylyl cyclase in Dictyostelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP induces a transient elevation of cGMP levels during early culmination of Dictyostelium minutum

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant cGMP-binding activity in non-chemotactic Dictyostelium discoideum mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane signaling in Dictyostelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streamers: Chemotactic Mutants of Dictyostelium discoideum with Altered Cyclic GMP Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9250676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/16.14.4317

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

ResearchGate publication ID

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