(Q41821858)

12 October 2017

Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted (English)

1 reference

12 October 2017

Smit JW

1

1 reference

12 October 2017

Schinkel AH

series ordinal

2

1 reference

12 October 2017

Weert B

series ordinal

3

1 reference

12 October 2017

Meijer DK

series ordinal

4

1 reference

12 October 2017

language of work or name

English

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publication date

1 May 1998

1 reference

British Journal of Pharmacology

12 October 2017

1 reference

12 October 2017

124

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12 October 2017

416-424

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12 October 2017

2

1 reference

The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

12 October 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

Mediation of cimetidine secretion by P-glycoprotein and a novel H(+)-coupled mechanism in cultured renal epithelial monolayers of LLC-PK1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

Mixed-effect modeling for detection and evaluation of drug interactions: digoxin-quinidine and digoxin-verapamil combinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Uptake and excretion of vecuronium bromide and pancuronium bromide in the isolated perfused rat liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Luminal transport system for H+/organic cations in the rat proximal tubule. Kinetics, dependence on pH; specificity as compared with the contraluminal organic cation-transport system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Drug excretion mediated by a new prototype of polyspecific transporter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

ABC Transporters: From Microorganisms to Man

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Transport of cationic amino acids by the mouse ecotropic retrovirus receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Investigations on the hepatic uptake systems for organic cations with a photoaffinity probe of procainamide ethobromide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Hepatic uptake and biliary excretion of organic cations--I. Characterization of three new model compounds

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Structure-pharmacokinetics relationship of quaternary ammonium compounds

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Effect of procainamide on renal tubular transport of cimetidine in the isolated perfused rat kidney.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Assay of vecuronium in plasma using solid-phase extraction, high-performance liquid chromatography and post-column ion-pair extraction with fluorimetric detection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Transport interactions of different organic cations during their excretion by the intact rat kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Mechanisms mediating renal secretion of organic anions and cations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Transport of procainamide in a kidney epithelial cell line LLC-PK1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Absorption and secretion of monoquaternary ammonium compounds by the isolated intestinal mucosa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Induction of hepatic P-glycoprotein enhances biliary excretion of vincristine in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701845

7 January 2021

Identifiers

DOI

10.1038/SJ.BJP.0701845

1 reference

12 October 2017

1 reference

12 October 2017

1 reference