(Q41835536)

12 October 2017

Development of small-molecule inhibitors targeting adipose triglyceride lipase (English)

1 reference

12 October 2017

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10

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12 October 2017

13

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12 October 2017

14

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12 October 2017

Gernot F Grabner

4

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Jakov Ivkovic

Jakov Ivkovic

7

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Christoph Heier

Christoph Heier

8

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Martina Schweiger

Martina Schweiger

2

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Thomas O Eichmann

Thomas O Eichmann

5

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Rolf Breinbauer

Rolf Breinbauer

15

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author name string

Nicole Mayer

1

1 reference

12 October 2017

Matthias Romauch

3

1 reference

12 October 2017

Elisabeth Fuchs

6

1 reference

12 October 2017

Irina Mrak

9

1 reference

12 October 2017

Gerald Höfler

11

1 reference

12 October 2017

Christian Fledelius

12

1 reference

12 October 2017

6 October 2013

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12 October 2017

Nature Chemical Biology

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12 October 2017

9

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12 October 2017

12

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12 October 2017

785-787

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio.1359

12 October 2017

0 references

cites work

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

The role of insulin resistance in the development of muscle wasting during cancer cachexia

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Origins of metabolic complications in obesity: ectopic fat accumulation. The importance of the qualitative aspect of lipotoxicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Obesity, insulin resistance and free fatty acids

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Lipid-induced insulin resistance: unravelling the mechanism

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Acyl-CoA synthesis, lipid metabolism and lipotoxicity.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Fate of fat: the role of adipose triglyceride lipase in lipolysis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Characterization of the human patatin-like phospholipase family

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Ceramides in insulin resistance and lipotoxicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Lipotoxicity: when tissues overeat

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

A novel clinical entity: triglyceride deposit cardiomyovasculopathy

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Synthesis and structure-activity relationship for a novel class of potent and selective carbamate-based inhibitors of hormone selective lipase with acute in vivo antilipolytic effects

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3829776

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1359

Hormone-sensitive lipase and monoacylglycerol lipase are both required for complete degradation of adipocyte triacylglycerol

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24096302

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/24096302

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1359

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

24096302

1 reference