(Q41837351)

English

Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1).

scientific article published on December 2008

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scholarly article

1 reference

Europe PubMed Central

12 October 2017

Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1). (English)

1 reference

Europe PubMed Central

12 October 2017

myotonic dystrophy

1 reference

based on heuristic

inferred from title

Benjamin L. Miller

6

1 reference

Europe PubMed Central

12 October 2017

Prakash B Palde

object named as

Prakash B Palde

4

0 references

Krzysztof Sobczak

2

object named as

Krzysztof Sobczak

1 reference

Europe PubMed Central

12 October 2017

author name string

Peter C Gareiss

1

1 reference

Europe PubMed Central

12 October 2017

Brian R McNaughton

3

1 reference

Europe PubMed Central

12 October 2017

Charles A Thornton

5

1 reference

Europe PubMed Central

12 October 2017

language of work or name

0 references

publication date

1 December 2008

1 reference

Europe PubMed Central

12 October 2017

Journal of the American Chemical Society

1 reference

Europe PubMed Central

12 October 2017

130

1 reference

Europe PubMed Central

12 October 2017

48

1 reference

Europe PubMed Central

12 October 2017

16254-16261

1 reference

Europe PubMed Central

12 October 2017

Two-vial, LC-MS identification of ephedrine receptors from a solution-phase dynamic combinatorial library of over 9000 components

1 reference

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Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners

1 reference

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Small-molecule aggregates inhibit amyloid polymerization

1 reference

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Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors

1 reference

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Dynamic combinatorial chemistry: on the road to fulfilling the promise

1 reference

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Guanidinoneomycin B Recognition of an HIV-1 RNA Helix

1 reference

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Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

1 reference

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Myotonic dystrophy: RNA-mediated muscle disease

1 reference

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Identification of a selective small-molecule ligand for HIV-1 frameshift-inducing stem-loop RNA from an 11,325 member resin bound dynamic combinatorial library

1 reference

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Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs

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1 reference

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Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

1 reference

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Resin-bound dynamic combinatorial chemistry

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Trisaccharide mimetics of the aminoglycoside antibiotic neomycin

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Ligand amplification in a dynamic combinatorial glycopeptide library

1 reference

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Clinical and molecular aspects of the myotonic dystrophies: a review.

1 reference

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Enzyme fragment complementation: a flexible high throughput screening assay technology

1 reference

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RNA−Ligand Interactions: Affinity and Specificity of Aminoglycoside Dimers and Acridine Conjugates to the HIV-1 Rev Response Element

1 reference

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A specific mechanism of nonspecific inhibition

1 reference

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Chemical and functional diversity of small molecule ligands for RNA.

1 reference

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Mechanisms of alternative pre-messenger RNA splicing

1 reference

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Identification of critical amino acid residues on human dihydrofolate reductase protein that mediate RNA recognition

1 reference

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Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy

1 reference

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Molecular recognition of DNA by small molecules

1 reference

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Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645920

6 June 2018

Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645920

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New promise in combinatorial chemistry: synthesis, characterization, and screening of small-molecule libraries in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2645920

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Application of capillary electrophoresis-electrospray ionization mass spectometry in the determination of molecular diversity

1 reference

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A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions

1 reference

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Macrocyclic helix-threading peptides for targeting RNA.

1 reference

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A tale of two targets: differential RNA selectivity of nucleobase-aminoglycoside conjugates.

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Size-specific ligands for RNA hairpin loops

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Dimeric aminoglycosides as antibiotics.

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Piperidine glycosides targeting the ribosomal decoding site.

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Design of novel antibiotics that bind to the ribosomal acyltransfer site

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Dynamic Combinatorial Chemistry

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Targeting RNA with Small Molecules

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Peptide quinoline conjugates: a new class of RNA-binding molecules

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Biochemical and thermodynamic characterization of compounds that bind to RNA hairpin loops: toward an understanding of selectivity

1 reference

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A Multifunctional RNA Recognition Motif in Poly(A)-specific Ribonuclease with Cap and Poly(A) Binding Properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/18998634

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based on heuristic

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Targeting RNA with small molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/18998634

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Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

1 reference

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Identifiers

10.1021/JA804398Y

1 reference

Europe PubMed Central

12 October 2017

1 reference

Europe PubMed Central

12 October 2017

1 reference

Europe PubMed Central

12 October 2017

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