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Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.
scientific article published on 27 July 2010
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
title
Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
author
Keiji Miyazawa
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
author name string
Yuto Kamiya
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
Kohei Miyazono
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
language of work or name
English
0 references
publication date
27 July 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
volume
285
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
issue
40
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
page(s)
30804-30813
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
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PubMed Central
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6 June 2018
Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation
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PubMed Central
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6 June 2018
A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling
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6 June 2018
NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor
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Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)
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6 June 2018
Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling
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6 June 2018
GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor
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6 June 2018
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
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6 June 2018
Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads
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Two major Smad pathways in TGF-beta superfamily signalling.
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6 June 2018
The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling
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6 June 2018
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
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6 June 2018
Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945574
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6 June 2018
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation
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PubMed Central
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6 June 2018
Structural basis of Smad2 recognition by the Smad anchor for receptor activation
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6 June 2018
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.
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6 June 2018
Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors
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6 June 2018
Determinants of specificity in TGF-beta signal transduction.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945574
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6 June 2018
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
1 reference
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PubMed Central
reference URL
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6 June 2018
The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.
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PubMed Central
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6 June 2018
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
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6 June 2018
A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity
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6 June 2018
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945574
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6 June 2018
Specificity of the inhibitory effects of Dad on TGF-beta family type I receptors, Thickveins, Saxophone, and Baboon in Drosophila.
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PubMed Central
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18 August 2018
dSmurf Selectively Degrades Decapentaplegic-activated MAD, and Its Overexpression Disrupts Imaginal Disc Development
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PubMed Central
reference URL
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18 August 2018
Smad6 inhibits signalling by the TGF-beta superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2945574
retrieved
18 August 2018
The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20663871
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20663871
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M110.166140
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PMC publication ID
2945574
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PubMed publication ID
20663871
1 reference
stated in
Europe PubMed Central
PMC publication ID
2945574
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20663871%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
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