(Q41842884)

English

Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids

scientific article published on 12 April 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

13 October 2017

Genetic adaptation of fatty-acid metabolism: a human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids (English)

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Europe PubMed Central

PMC publication ID

13 October 2017

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genetic adaptation

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based on heuristic

inferred from title

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Thomas Meitinger

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Igor Rudan

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Cornelia M. van Duijn

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Cornelia van Duijn

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Mark Joseph Daly

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Mark J Daly

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13 October 2017

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Ulf Gyllensten

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James F. Wilson

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James F Wilson

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Harry Campbell

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Ben Oostra

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Peter P. Pramstaller

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Peter P Pramstaller

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Asa Johansson

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Wilmar Igl

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Ghazal Zaboli

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Lars Feuk

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author name string

Anna C V Johansson

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Manuel A Rivas

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Gerd Schmitz

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Alan F Wright

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publication date

12 April 2012

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13 October 2017

American Journal of Human Genetics

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13 October 2017

90

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5

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13 October 2017

809-820

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Europe PubMed Central

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13 October 2017

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

1 reference

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Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome

1 reference

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The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

1 reference

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Testing for an unusual distribution of rare variants

1 reference

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1 reference

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phangorn: phylogenetic analysis in R

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Statistical analysis strategies for association studies involving rare variants

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Integrating common and rare genetic variation in diverse human populations

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Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study

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Biological, clinical and population relevance of 95 loci for blood lipids

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6 June 2018

Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios

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Complete Khoisan and Bantu genomes from southern Africa

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Genetic determinants of circulating sphingolipid concentrations in European populations

1 reference

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A 'desaturase hypothesis' for atherosclerosis: Janus-faced enzymes in omega-6 and omega-3 polyunsaturated fatty acid metabolism.

1 reference

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6 June 2018

Fat and fatty acid terminology, methods of analysis and fat digestion and metabolism: a background review paper

1 reference

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Genotype imputation

1 reference

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The Sequence Alignment/Map format and SAMtools

1 reference

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Signals of recent positive selection in a worldwide sample of human populations

1 reference

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Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study

1 reference

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Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

1 reference

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Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

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Common variants at 30 loci contribute to polygenic dyslipidemia

1 reference

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Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis

1 reference

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6 June 2018

Runs of homozygosity in European populations

1 reference

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Genetically determined variation in polyunsaturated fatty acid metabolism may result in different dietary requirements

1 reference

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Mapping the genetic architecture of gene expression in human liver

1 reference

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Localizing recent adaptive evolution in the human genome

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Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids

1 reference

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Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3

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1 reference

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1 reference

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1 reference

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Evidence for the unique function of docosahexaenoic acid during the evolution of the modern hominid brain

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk

1 reference

https://pubmed.ncbi.nlm.nih.gov/22503634

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJHG.2012.03.014

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

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