(Q41846529)

English

Discovery and structure-activity relationships of modified salicylanilides as cell permeable inhibitors of poly(ADP-ribose) glycohydrolase (PARG).

scientific article published on 8 July 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Discovery and structure-activity relationships of modified salicylanilides as cell permeable inhibitors of poly(ADP-ribose) glycohydrolase (PARG). (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

Jamin D Steffen

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Donna L Coyle

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Komath Damodaran

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Paul Beroza

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Myron K Jacobson

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

0 references

publication date

8 July 2011

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

54

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

15

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

5403-5413

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

The ups and downs of tannins as inhibitors of poly(ADP-ribose)glycohydrolase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Identification of a Regulatory Segment of Poly(ADP-ribose) Glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

PARP inhibition: PARP1 and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Selective down-regulation of nuclear poly(ADP-ribose) glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly(ADP-ribose) (PAR) polymer is a death signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Inhibition of poly(ADP-ribose) polymerase in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly(ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Target-related affinity profiling: Telik's lead discovery technology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Introduction to poly(ADP-ribose) metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

PARP inhibitors for cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Cytoprotective effect of gallotannin in oxidatively stressed HaCaT keratinocytes: the role of poly(ADP-ribose) metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Isolation and characterization of the cDNA encoding bovine poly(ADP-ribose) glycohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Effect of DNA intercalators on poly(ADP-ribose) glycohydrolase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly(ADP-ribose) in the cellular response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Inhibitory effect of tannin on poly(ADP-ribose) glycohydrolase from human placenta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Poly(ADP-ribose) levels in carcinogen-treated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

Pyridine nucleotide levels as a function of growth in normal and transformed 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

5 June 2018

The roles of poly(ADP-ribose)-metabolizing enzymes in alkylation-induced cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

18 August 2018

Poly(ADP-ribose) glycohydrolase as a target for neuroprotective intervention: assessment of currently available pharmacological tools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

18 August 2018

Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

18 August 2018

Antioxidant and pro-oxidant effects of tannins in digestive cells of the freshwater mussel Unio tumidus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

18 August 2018

Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

18 August 2018

Effect of carcinogenic N-alkyl-N-nitroso compounds on nicotinamide adenine dinucleotide metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150619

18 August 2018

Metabolic consequences of DNA damage: the role of poly (ADP-ribose) polymerase as mediator of the suicide response

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid assay of poly(ADP-ribose) glycohydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoglycosidic cleavage of branched polymers by poly(ADP-ribose) glycohydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syntheses of photoactive analogues of adenosine diphosphate (hydroxymethyl)pyrrolidinediol and photoaffinity labeling of poly(ADP-ribose) glycohydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological inhibition of poly(ADP-ribose) polymerase in cardiovascular disorders: future directions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21692479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM200325S

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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