(Q37846088)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

review article

1 reference

title

The ups and downs of tannins as inhibitors of poly(ADP-ribose)glycohydrolase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Christian Blenn

series ordinal

1

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23 January 2020

Philippe Wyrsch

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Felix R Althaus

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

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publication date

22 February 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

2

1 reference

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23 January 2020

page(s)

1854-1877

1 reference

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Creative Commons Attribution 4.0 International

23 January 2020

copyright license

start time

22 February 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

1 reference

12 December 2020

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1 reference

12 December 2020

Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.

1 reference

12 December 2020

The poly(ADP-ribose) glycohydrolase inhibitor gallotannin blocks oxidative astrocyte death.

1 reference

12 December 2020

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

1 reference

12 December 2020

A bidirectional promoter connects the poly(ADP-ribose) polymerase 2 (PARP-2) gene to the gene for RNase P RNA. structure and expression of the mouse PARP-2 gene

1 reference

12 December 2020

Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism.

1 reference

12 December 2020

Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

1 reference

12 December 2020

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

1 reference

12 December 2020

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

1 reference

12 December 2020

Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties

1 reference

12 December 2020

Transcriptional suppression of the HIV promoter by natural compounds

1 reference

12 December 2020

Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat.

1 reference

12 December 2020

Mouse mammary tumor virus gene expression is suppressed by oligomeric ellagitannins, novel inhibitors of poly(ADP-ribose) glycohydrolase

1 reference

12 December 2020

SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase

1 reference

12 December 2020

Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid synthesizing nuclear enzyme

1 reference

12 December 2020

UV irradiation inhibits ABC transporters via generation of ADP-ribose by concerted action of poly(ADP-ribose) polymerase-1 and glycohydrolase

1 reference

12 December 2020

Changes in the activities and gene expressions of poly(ADP-ribose) glycohydrolases during the differentiation of human promyelocytic leukemia cell line HL-60.

1 reference

12 December 2020

Cytoprotective effect of gallotannin in oxidatively stressed HaCaT keratinocytes: the role of poly(ADP-ribose) metabolism

1 reference

12 December 2020

Tannins elevate the level of poly(ADP-ribose) in HeLa cell extracts.

1 reference

12 December 2020

Dual role for poly(ADP-ribose)polymerase-1 and -2 and poly(ADP-ribose)glycohydrolase as DNA-repair and pro-apoptotic factors in rat germinal cells exposed to nitric oxide donors

1 reference

12 December 2020

Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice

1 reference

12 December 2020

Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments

1 reference

12 December 2020

Inhibition of poly(ADP-ribose) glycohydrolase by gallotannin selectively up-regulates expression of proinflammatory genes

1 reference

12 December 2020

1 reference

12 December 2020

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

1 reference

12 December 2020

TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

1 reference

12 December 2020

Poly(ADP-ribose) glycohydrolase as a target for neuroprotective intervention: assessment of currently available pharmacological tools

1 reference

12 December 2020

A nonradiometric, high-throughput assay for poly(ADP-ribose) glycohydrolase (PARG): application to inhibitor identification and evaluation

1 reference

12 December 2020

Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.

1 reference

12 December 2020

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

1 reference

12 December 2020

Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury

1 reference

12 December 2020

PARG activity mediates intestinal injury induced by splanchnic artery occlusion and reperfusion

1 reference

12 December 2020

An epigenetic code for DNA damage repair pathways?

1 reference

12 December 2020

The role of poly(ADP-ribose) in the DNA damage signaling network

1 reference

12 December 2020

Gallotannin inhibits the expression of chemokines and inflammatory cytokines in A549 cells

1 reference

12 December 2020

Poly(ADP-ribose) glycohydrolase silencing protects against H2O2-induced cell death

1 reference

12 December 2020

Poly(ADP-ribose): novel functions for an old molecule

1 reference

12 December 2020

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

1 reference

12 December 2020

Poly(ADP-ribose) (PAR) polymer is a death signal

1 reference

12 December 2020

Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase

1 reference

12 December 2020

The involvement of ATP produced via (ADP-Ribose)n in the maintenance of DNA replication apparatus during DNA repair

1 reference

12 December 2020

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents

1 reference

12 December 2020

Differential effects of tannic acid on cisplatin induced nephrotoxicity in rats.

1 reference

12 December 2020

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

1 reference

12 December 2020

Modulation of transcription by PARP-1: consequences in carcinogenesis and inflammation.

1 reference

12 December 2020

Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity.

1 reference

12 December 2020

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

1 reference

12 December 2020

Intranasal administration of a PARG inhibitor profoundly decreases ischemic brain injury

1 reference

12 December 2020

Effects of chemically defined tannins on poly (ADP-ribose) glycohydrolase activity

1 reference

12 December 2020

Poly(ADP-ribose) makes a date with death

1 reference

12 December 2020

Nutraceuticals: facts and fiction

1 reference

12 December 2020

PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

1 reference

12 December 2020

The roles of poly(ADP-ribose)-metabolizing enzymes in alkylation-induced cell death.

1 reference

12 December 2020

Tannic acid prevents azidothymidine (AZT) induced hepatotoxicity and genotoxicity along with change in expression of PARG and histone H3 acetylation

1 reference

12 December 2020

Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation

1 reference

12 December 2020

The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes

1 reference

12 December 2020

Gallotannin ameliorates the development of streptozotocin-induced diabetic nephropathy by preventing the activation of PARP.

1 reference

12 December 2020

The role of poly(ADP-ribosyl)ation in epigenetic events.

1 reference

12 December 2020

Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death

1 reference

12 December 2020

Epigenetics: poly(ADP-ribosyl)ation of PARP-1 regulates genomic methylation patterns

1 reference

12 December 2020

Disruption of poly(ADP-ribose) homeostasis affects spermiogenesis and sperm chromatin integrity in mice.

1 reference

12 December 2020

A specific isoform of poly(ADP-ribose) glycohydrolase is targeted to the mitochondrial matrix by a N-terminal mitochondrial targeting sequence.

1 reference

12 December 2020

Tannins: current knowledge of food sources, intake, bioavailability and biological effects.

1 reference

12 December 2020

Radiation-induced mitotic catastrophe in PARG-deficient cells.

1 reference

12 December 2020

Discovery of novel poly(ADP-ribose) glycohydrolase inhibitors by a quantitative assay system using dot-blot with anti-poly(ADP-ribose).

1 reference

12 December 2020

Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

1 reference

12 December 2020

Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy.

1 reference

12 December 2020

AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

1 reference

12 December 2020

Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink.

1 reference

12 December 2020

Enhanced DNA accessibility and increased DNA damage induced by the absence of poly(ADP-ribose) hydrolysis

1 reference

12 December 2020

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

1 reference

12 December 2020

Poly(ADP-ribose)glycohydrolase is an upstream regulator of Ca2+ fluxes in oxidative cell death

1 reference

12 December 2020

Poly(ADP-ribose) metabolism is essential for proper nucleoprotein exchange during mouse spermiogenesis

1 reference

12 December 2020

Targeted therapies: PARP inhibitor olaparib is safe and effective in patients with BRCA1 and BRCA2 mutations

1 reference

12 December 2020

Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis

1 reference

12 December 2020

The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells

1 reference

12 December 2020

Therapeutic potential of poly(ADP-ribose) polymerase inhibitor AG014699 in human cancers with mutated or methylated BRCA1 or BRCA2.

1 reference

12 December 2020

Tannic acid ameliorates doxorubicin-induced cardiotoxicity and potentiates its anti-cancer activity: potential role of tannins in cancer chemotherapy

1 reference

12 December 2020

Poly(ADP-ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic

1 reference

12 December 2020

PARP and cancer--if it's broke, don't fix it.

1 reference

12 December 2020

Inhibitory effect of tannin on poly(ADP-ribose) glycohydrolase from human placenta

1 reference

12 December 2020

Purification and characterization of poly(ADP-ribose) glycohydrolase. Different modes of action on large and small poly(ADP-ribose)

1 reference

12 December 2020

Purification and Properties of a Glycohydrolase from Calf Thymus Splitting Ribose-Ribose Linkages of Poly(Adenosine Diphosphate Ribose)

1 reference

12 December 2020

A macrocircular ellagitannin, oenothein B, suppresses mouse mammary tumor gene expression via inhibition of poly(ADP-ribose) glycohydrolase

1 reference

12 December 2020

Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol

1 reference

12 December 2020

Mode of action of poly(ADP-ribose) glycohydrolase

1 reference

12 December 2020

Novel inhibitors of poly(ADP-ribose) glycohydrolase

1 reference

12 December 2020

Inhibitory effect of tannic acid on human immunodeficiency virus promoter activity induced by 12-O-tetra decanoylphorbol-13-acetate in Jurkat T-cells

1 reference

12 December 2020

Natural polyphenols (vegetable tannins) as drugs: possible modes of action

1 reference

12 December 2020

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

12 December 2020

10.3390/MOLECULES16021854

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21343889%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

21343889

1 reference