(Q40146768)

English

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents

scientific article published on 11 April 2007

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Europe PubMed Central

PubMed publication ID

17 September 2017

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

ataxia telangiectasia

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based on heuristic

inferred from title

Michael J. Hendzel

object named as

Michael J Hendzel

5

0 references

Valina L. Dawson

object named as

Valina L Dawson

3

0 references

4

object named as

Ted M Dawson

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

author name string

Jean-François Haince

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Sergei Kozlov

2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Martin F Lavin

6

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Guy G Poirier

7

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

language of work or name

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publication date

11 April 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

17 September 2017

282

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Europe PubMed Central

PubMed publication ID

17 September 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

16441-16453

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

The role of double-strand break repair — insights from human genetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

ATM signaling and genomic stability in response to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

High doses of SN1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

PARP-1, a determinant of cell survival in response to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribose) (PAR) polymer is a death signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

The role of poly(ADP-ribose) in the DNA damage signaling network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Inhibition of poly(ADP-ribose) polymerase in cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Cell cycle perturbations following DNA damage in the presence of ADP-ribosylation inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

BubR1 is involved in regulation of DNA damage responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribose) is required for spindle assembly and structure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribose) reactivates stalled DNA topoisomerase I and Induces DNA strand break resealing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Ionizing radiation activates the ATM kinase throughout the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

ATM associates with and phosphorylates p53: mapping the region of interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Methods for biochemical study of poly(ADP-ribose) metabolism in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Intracellular delivery of proteins with a new lipid-mediated delivery system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

The ATM-mediated DNA-damage response: taking shape.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Does gammaH2AX foci formation depend on the presence of DNA double strand breaks?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

A comparative study of using comet assay and gammaH2AX foci formation in the detection of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

PARP-1 modifies the effectiveness of p53-mediated DNA damage response.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

The macro domain is an ADP-ribose binding module

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608406200

21 January 2018

Identifiers

10.1074/JBC.M608406200

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

ResearchGate publication ID

0 references

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