(Q41852151)

13 October 2017

Inhibition of IgE-mediated secretion from human basophils with a highly selective Bruton's tyrosine kinase, Btk, inhibitor (English)

1 reference

13 October 2017

Donald MacGlashan

1

1 reference

13 October 2017

Lee A Honigberg

2

1 reference

13 October 2017

Ashley Smith

3

1 reference

13 October 2017

Joseph Buggy

4

1 reference

13 October 2017

John T Schroeder

5

1 reference

13 October 2017

language of work or name

1 reference

14 January 2011

1 reference

International Immunopharmacology

13 October 2017

1 reference

13 October 2017

11

1 reference

13 October 2017

4

1 reference

13 October 2017

475-479

1 reference

describes a project that uses

13 October 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3345890/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Human basophils secrete IL-3: evidence of autocrine priming for phenotypic and functional responses in allergic disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Polymerization of actin does not regulate desensitization in human basophils

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

A quantitative analysis of kinase inhibitor selectivity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

The phosphoinositide 3-kinase pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

An automated continuous-flow system for the extraction and fluorometric analysis of histamine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Oscillations in free cytosolic calcium during IgE-mediated stimulation distinguish human basophils from human mast cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Differential mechanisms in the stimulus-secretion coupling in human basophils: evidence for a protein-kinase-C-dependent and a protein-kinase-C-independent route

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Basophil counting with a new staining method using alcian blue

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Inducing an anergic state in mast cells and basophils without secretion

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Loss of syk kinase during IgE-mediated stimulation of human basophils

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345890

Phosphatidylinositol-3 kinase regulates p21ras activation during IgE-mediated stimulation of human basophils

18 August 2018

1 reference

12 December 2020

The tyrosine kinases p53/56lyn and p72syk are differentially expressed at the protein level but not at the messenger RNA level in nonreleasing human basophils

1 reference

12 December 2020

Pharmacology of IgE-mediated desensitization of human basophils: effects of protein kinase C and src-family kinase inhibitors

1 reference

12 December 2020

Measuring leukotrienes of slow reacting substance of anaphylaxis: development of a specific radioimmunoassay

1 reference

12 December 2020

Biphasic Ca2+ responses in human basophils. Evidence that the initial transient elevation associated with the mobilization of intracellular calcium is an insufficient signal for degranulation

1 reference

12 December 2020

Nonspecific Desensitization, Functional Memory, and the Characteristics of SHIP Phosphorylation following IgE-Mediated Stimulation of Human Basophils

1 reference

12 December 2020

10.1016/J.INTIMP.2010.12.018

Identifiers

DOI

1 reference

release_oucgcvqgr5ertclnlq6234v6wa

13 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oucgcvqgr5ertclnlq6234v6wa

24 November 2022

mapped directly with Wikidata item

1 reference

13 October 2017

PubMed publication ID

21238622

1 reference