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Dissociated GαGTP and Gβγ protein subunits are the major activated form of heterotrimeric Gi/o proteins.
scientific article published on 4 December 2013
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
title
Dissociated GαGTP and Gβγ protein subunits are the major activated form of heterotrimeric Gi/o proteins
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
author
Josef Lazar
series ordinal
2
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Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Josef Lazar
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
author name string
Alexey Bondar
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1
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Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
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2 March 2020
language of work or name
English
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publication date
4 December 2013
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Europe PubMed Central
PMC publication ID
3894313
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
number of pages
11
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Journal of Biological Chemistry
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Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
volume
289
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Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
issue
3
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Europe PubMed Central
PMC publication ID
3894313
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
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2 March 2020
page(s)
1271-1281
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Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3894313/fullTextXML
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Two distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunits
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G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK)
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Some G protein heterotrimers physically dissociate in living cells
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Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors
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G protein betagamma11 complex translocation is induced by Gi, Gq and Gs coupling receptors and is regulated by the alpha subunit type
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G Protein activation without subunit dissociation depends on a G{alpha}(i)-specific region.
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12 December 2020
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Structural basis of activity and subunit recognition in G protein heterotrimers
1 reference
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Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits
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Identifiers
DOI
10.1074/JBC.M113.493643
1 reference
stated in
Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PMC publication ID
3894313
1 reference
stated in
Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PubMed publication ID
24307173
1 reference
stated in
Europe PubMed Central
PMC publication ID
3894313
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307173%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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