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English
Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine
scientific article published on 19 January 2015
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4333055
retrieved
13 October 2017
title
Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4333055
retrieved
13 October 2017
main subject
proteolysis
1 reference
based on heuristic
inferred from title
corrigendum / erratum
Erratum: Coordinated gripping of substrate by subunits of an AAA+ proteolytic machine
1 reference
stated in
Crossref
DOI
10.1038/NCHEMBIO0415-299A
retrieved
12 July 2019
reference URL
http://api.crossref.org/works?select=update-to&filter=doi:10.1038/NCHEMBIO0415-299A
author
Robert T Sauer
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
author name string
Ohad Iosefson
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
Andrew R Nager
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
Tania A Baker
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
publication date
19 January 2015
1 reference
stated in
Europe PubMed Central
PMCID
4333055
retrieved
13 October 2017
published in
Nature Chemical Biology
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
volume
11
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
page(s)
201-206
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nchembio.1732
0 references
cites work
Mechanochemical basis of protein degradation by a double-ring AAA+ machine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Substrate delivery by the AAA+ ClpX and ClpC1 unfoldases activates the mycobacterial ClpP1P2 peptidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
The ClpXP protease unfolds substrates using a constant rate of pulling but different gears.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Conformational switching of the 26S proteasome enables substrate degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Dynamic and static components power unfolding in topologically closed rings of a AAA+ proteolytic machine
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Stepwise unfolding of a β barrel protein by the AAA+ ClpXP protease.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
ClpXP, an ATP-powered unfolding and protein-degradation machine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
ClpX(P) generates mechanical force to unfold and translocate its protein substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Single-molecule protein unfolding and translocation by an ATP-fueled proteolytic machine.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
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5 June 2018
AAA+ proteases: ATP-fueled machines of protein destruction
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
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5 June 2018
ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle
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PubMed Central
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5 June 2018
Control of substrate gating and translocation into ClpP by channel residues and ClpX binding.
1 reference
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PubMed Central
reference URL
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5 June 2018
Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
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5 June 2018
Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
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5 June 2018
Polypeptide translocation by the AAA+ ClpXP protease machine.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
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5 June 2018
Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Distinct static and dynamic interactions control ATPase-peptidase communication in a AAA+ protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Partitioning between unfolding and release of native domains during ClpXP degradation determines substrate selectivity and partial processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Role of the processing pore of the ClpX AAA+ ATPase in the recognition and engagement of specific protein substrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
AAA+ superfamily ATPases: common structure--diverse function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Effects of protein stability and structure on substrate processing by the ClpXP unfolding and degradation machine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Molecular determinants of complex formation between Clp/Hsp100 ATPases and the ClpP peptidase.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Mutational studies on HslU and its docking mode with HslV
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
5 June 2018
Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Diverse pore loops of the AAA+ ClpX machine mediate unassisted and adaptor-dependent recognition of ssrA-tagged substrates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Protein unfolding by a AAA+ protease is dependent on ATP-hydrolysis rates and substrate energy landscapes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Mutations in p97/VCP induce unfolding activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Characterization of mutants of the Escherichia coli AAA protease, FtsH, carrying a mutation in the central pore region.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Substrate specific consequences of central pore mutations in the i-AAA protease Yme1 on substrate engagement
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
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18 August 2018
Rebuilt AAA + motors reveal operating principles for ATP-fuelled machines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
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18 August 2018
Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Conserved Pore Residues in the AAA Protease FtsH Are Important for Proteolysis and Its Coupling to ATP Hydrolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333055
retrieved
18 August 2018
Identifiers
DOI
10.1038/NCHEMBIO.1732
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
PMCID
4333055
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
PubMed ID
25599533
1 reference
stated in
Europe PubMed Central
PMCID
4333055
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25599533%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 May 2020
ResearchGate publication ID
271533683
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