(Q41877780)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Human lactate dehydrogenase a inhibitors: a molecular dynamics investigation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

B Mario Pinto

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

language of work or name

English

0 references

publication date

17 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

e86365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

6 March 2020

copyright license

start time

17 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase

5 June 2018

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Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase

5 June 2018

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Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors

5 June 2018

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5 June 2018

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Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation

5 June 2018

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5 June 2018

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5 June 2018

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Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

5 June 2018

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Top leads for swine influenza A/H1N1 virus revealed by steered molecular dynamics approach.

5 June 2018

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Single-molecule pulling simulations can discern active from inactive enzyme inhibitors

5 June 2018

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Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

5 June 2018

1 reference

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Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials

5 June 2018

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

5 June 2018

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AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

5 June 2018

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LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer

5 June 2018

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R.E.DD.B.: a database for RESP and ESP atomic charges, and force field libraries

5 June 2018

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Canonical sampling through velocity rescaling

5 June 2018

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Comparison of multiple Amber force fields and development of improved protein backbone parameters

5 June 2018

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Crystalline lactic dehydrogenase from heart muscle

5 June 2018

1 reference

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The Amber biomolecular simulation programs

5 June 2018

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The approach to the Michaelis complex in lactate dehydrogenase: the substrate binding pathway

5 June 2018

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Why do cancers have high aerobic glycolysis?

5 June 2018

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Calculating potentials of mean force from steered molecular dynamics simulations

5 June 2018

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Development and testing of a general amber force field

5 June 2018

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Bias and error in estimates of equilibrium free-energy differences from nonequilibrium measurements

5 June 2018

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On respiratory impairment in cancer cells

5 June 2018

1 reference

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Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis

5 June 2018

1 reference

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Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase

5 June 2018

1 reference

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Canonical dynamics: Equilibrium phase-space distributions

5 June 2018

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Lactate dehydrogenase M-subunit deficiency: a new type of hereditary exertional myopathy

5 June 2018

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5 June 2018

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Toward quantitative estimates of binding affinities for protein-ligand systems involving large inhibitor compounds: a steered molecular dynamics simulation route.

18 August 2018

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Theoretical studies of HIV-1 reverse transcriptase inhibition.

18 August 2018

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Importance of the lactate dehydrogenase quaternary structure in theoretical calculations

18 August 2018

1 reference

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Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins

18 August 2018

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Lactate dehydrogenase-5 (LDH-5) expression in human gastric cancer: association with hypoxia-inducible factor (HIF-1alpha) pathway, angiogenic factors production and poor prognosis

18 August 2018

1 reference

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Nonequilibrium Equality for Free Energy Differences

18 August 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086365

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086365

Free energy calculation from steered molecular dynamics simulations using Jarzynski’s equality

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086365

Molecular dynamics with coupling to an external bath

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086365

Lactate Dehydrogenase 5 Expression in Operable Colorectal Cancer: Strong Association With Survival and Activated Vascular Endothelial Growth Factor Pathway—A Report of the Tumour Angiogenesis Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086365

Selective Inhibitors of Human Lactate Dehydrogenases and Lactate Dehydrogenase from the Malarial ParasitePlasmodiumfalciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086365

Removal of substrate inhibition in a lactate dehydrogenase from human muscle by a single residue change

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24466056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Design and synthesis of new enzymes based on the lactate dehydrogenase framework

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24466056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

LACTIC DEHYDROGENASE IN HUMAN NEOPLASTIC TISSUES

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24466056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0086365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

24466056

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24466056%20AND%20SRC:MED&resulttype=core&format=json