(Q41906544)

English

Differential modulation of doxorubicin toxicity to multidrug and intrinsically drug resistant cell lines by anti-oestrogens and their major metabolites

scientific article published on June 1, 1993

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Differential modulation of doxorubicin toxicity to multidrug and intrinsically drug resistant cell lines by anti-oestrogens and their major metabolites (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

multiple drug resistance

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

4

object named as

I J Stratford

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

5

object named as

A. L. Harris

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

author name string

J. Kirk

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

S. Houlbrook

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

N. S. Stuart

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

I. J. Stratford

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

J. Carmichael

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

language of work or name

0 references

publication date

1 June 1993

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

full work available at URL

https://europepmc.org/articles/pmc1968530?pdf=render

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

https://europepmc.org/articles/PMC1968530

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

https://europepmc.org/articles/PMC1968530?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7685615

17 August 2024

http://www.nature.com/articles/bjc1993224.pdf

Portable Document Format

1 reference

10.1038/BJC.1993.224

https://api.crossref.org/works/10.1038/BJC.1993.224

17 August 2024

http://www.nature.com/articles/bjc1993224

1 reference

10.1038/BJC.1993.224

https://api.crossref.org/works/10.1038/BJC.1993.224

17 August 2024

British Journal of Cancer

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

67

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1189-1195

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Determination and pharmacology of a new hydroxylated metabolite of tamoxifen observed in patient sera during therapy for advanced breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Pharmacology of tamoxifen in laboratory animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Reversal of acquired resistance to doxorubicin in P388 murine leukemia cells by tamoxifen and other triparanol analogues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Breast tumor cell lines from pleural effusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

A human cell line from a pleural effusion derived from a breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Effect of tamoxifen, a nonsteroidal antiestrogen, on phospholipid/calcium-dependent protein kinase and phosphorylation of its endogenous substrate proteins from the rat brain and ovary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Effect of verapamil and other agents on the distribution of anthracyclines and on reversal of drug resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Phorbol esters induce multidrug resistance in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Modulation of induced resistance to adriamycin in two human breast cancer cell lines with tamoxifen or perhexiline maleate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Inhibition of protein kinase C by tamoxifen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Cyclosporin A and its analogues as modifiers of adriamycin and vincristine resistance in a multi-drug resistant human lung cancer cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Interactions among membrane transport systems: anthracyclines, calcium antagonists and anti-estrogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Effects of the pH dependence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

The biochemistry of P-glycoprotein-mediated multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Toremifene: pharmacologic and pharmacokinetic basis of reversing multidrug resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Reversal of acquired resistance to adriamycin in CHO cells by tamoxifen and 4-hydroxy tamoxifen: role of drug interaction with alpha 1 acid glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Development of antiestrogens and their use in breast cancer: eighth Cain memorial award lecture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Preclinical studies with toremifene as an antitumor agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Cell surface actions of adriamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Reversal of multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in multidrug-resistant cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Protein kinase C phosphorylates P-glycoprotein in multidrug resistant human KB carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Binding of an optically pure photoaffinity analogue of verapamil, LU-49888, to P-glycoprotein from multidrug-resistant human leukemic cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Cystic fibrosis. Channelling our thoughts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Expression of P-glycoprotein in breast cancer tissue and in vitro resistance to doxorubicin and vincristine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Analysis of P-glycoprotein phosphorylation in HL60 cells isolated for resistance to vincristine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Keynote address: Multidrug resistance: A pleiotropic response to cytotoxic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

High-dose tamoxifen as an enhancer of etoposide cytotoxicity. Clinical effects and in vitro assessment in p-glycoprotein expressing cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

3 The Molecular Basis for the Action of Some DNA-Binding Drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

5 June 2018

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

18 August 2018

Effect of the calmodulin inhibitor trifluoperazine on phosphorylation of P-glycoprotein and topoisomerase II: relationship to modulation of subcellular distribution, DNA damage and cytotoxicity of doxorubicin in multidrug resistant L1210 mouse leuke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1968530

18 August 2018

Intrinsic multidrug resistance phenotype of Chinese hamster (rodent) cells in comparison to human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of specific interactions between protein kinase C and triphenylethylenes in inhibition of the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of 4-hydroxy-N-desmethyltamoxifen and other tamoxifen metabolites in human biological fluids during tamoxifen treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein joins transport family

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and pharmacological effects of toremifene metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of the tolerance and pharmacokinetics of toremifene in patients with cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolites, pharmacodynamics, and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,25-dihydroxyvitamin D3 specifically binds to a human breast cancer cell line (T47D) and stimulates growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen is a calmodulin antagonist in the activation of cAMP phosphodiesterase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Volume regulation of Chinese hamster ovary cells in anisoosmotic media

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen metabolites in patients on long-term adjuvant therapy for breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7685615

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.1993.224

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q41906544&oldid=2233039759"