(Q41911121)

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Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells.

scientific article published on 5 October 2015

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Wiskott-Aldrich syndrome

1 reference

based on heuristic

inferred from title

protein deficiency

1 reference

based on heuristic

inferred from title

Selina J Keppler

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Marianne Burbage

3

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Bruno Frederico

5

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26 February 2020

7

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26 February 2020

author name string

Francesca Gasparrini

2

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26 February 2020

Shweta Aggarwal

4

1 reference

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PMC publication ID

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26 February 2020

Raif S Geha

6

1 reference

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PMC publication ID

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26 February 2020

Andreas Bruckbauer

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Facundo D Batista

9

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26 February 2020

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publication date

6 October 2015

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26 February 2020

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

43

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26 February 2020

4

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Europe PubMed Central

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26 February 2020

660-673

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Europe PubMed Central

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26 February 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4622935/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Erratum: Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WIP: more than a WASp-interacting protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

B-cell expansion and lymphomagenesis induced by chronic CD40 signaling is strictly dependent on CD19.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Context-specific BAFF-R signaling by the NF-κB and PI3K pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

N-wasp is essential for the negative regulation of B cell receptor signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Genome engineering using the CRISPR-Cas9 system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Multiplex genome engineering using CRISPR/Cas systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Wiskott-Aldrich syndrome protein (WASP) and N-WASP are critical for peripheral B-cell development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

New insights into the biology of Wiskott-Aldrich syndrome (WAS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Actin depolymerization transduces the strength of B-cell receptor stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Chemokine requirements for B cell entry to lymph nodes and Peyer's patches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Cd19-dependent activation of Akt kinase in B-lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Signal transduction by lymphocyte antigen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

5 June 2018

Antigen receptor tail clue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

16 June 2018

WIP null mice display a progressive immunological disorder that resembles Wiskott-Aldrich syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

18 August 2018

B cell ligand discrimination through a spreading and contraction response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

18 August 2018

WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

18 August 2018

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

18 August 2018

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

18 August 2018

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

18 August 2018

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622935

18 August 2018

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/26453379

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/26453379

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/26453379

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.IMMUNI.2015.09.004

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26453379%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

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