(Q35891625)

English

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.

scientific article published in February 2012

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scholarly article

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22 January 2020

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice (English)

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22 January 2020

Wiskott-Aldrich syndrome

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Siobhan O Burns

2

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22 January 2020

Miguel De La Fuente

3

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22 January 2020

4

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22 January 2020

12

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22 January 2020

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22 January 2020

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22 January 2020

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22 January 2020

Francesco Frugoni

20

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22 January 2020

Lisa Westerberg

33

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22 January 2020

Adrian Thrasher

34

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22 January 2020

Luigi D Notarangelo

35

object named as

Luigi D Notarangelo

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22 January 2020

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Mike Recher

1

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22 January 2020

Carin Dahlberg

5

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22 January 2020

Jolan E Walter

6

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22 January 2020

Kristin Moffitt

7

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22 January 2020

Divij Mathew

8

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22 January 2020

Nadine Honke

9

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22 January 2020

Philipp A Lang

10

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22 January 2020

Laura Patrizi

11

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22 January 2020

Fabio Candotti

16

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22 January 2020

Kari Nadeau

17

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22 January 2020

Ottavia M Delmonte

19

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22 January 2020

Angela B Ferraz Fomin

21

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22 January 2020

David Buchbinder

22

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22 January 2020

Emma Maria Lundequist

23

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22 January 2020

Michel J Massaad

24

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22 January 2020

George C Tsokos

25

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22 January 2020

John Hartwig

26

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22 January 2020

John Manis

27

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22 January 2020

Cox Terhorst

28

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22 January 2020

Raif S Geha

29

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22 January 2020

Scott Snapper

30

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22 January 2020

Karl S Lang

31

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22 January 2020

Richard Malley

32

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22 January 2020

Eva Csizmadia

15

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22 January 2020

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publication date

1 February 2012

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22 January 2020

1 reference

Europe PubMed Central

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22 January 2020

119

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22 January 2020

12

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22 January 2020

2819-2828

1 reference

Europe PubMed Central

PMC publication ID

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22 January 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3327460/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

WASP: a key immunological multitasker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Follicular shuttling of marginal zone B cells facilitates antigen transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Testing gene function early in the B cell lineage in mb1-cre mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Clinical course of patients with WASP gene mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Defects in T-cell-mediated immunity to influenza virus in murine Wiskott-Aldrich syndrome are corrected by oncoretroviral vector-mediated gene transfer into repopulating hematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Autoimmunity in Wiskott-Aldrich syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Autoimmunity in Wiskott-Aldrich syndrome: risk factors, clinical features, and outcome in a single-center cohort of 55 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Protective T cell-independent antiviral antibody responses are dependent on complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Defective actin polymerization in EBV-transformed B-cell lines from patients with the Wiskott-Aldrich syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Systemic exposure to irradiated apoptotic cells induces autoantibody production

1 reference

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11 July 2018

Macrophage scavenger receptor MARCO: in vitro and in vivo regulation and involvement in the anti-bacterial host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

A multiinstitutional survey of the Wiskott-Aldrich syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

11 July 2018

Immunodeficiency in the Wiskott-Aldrich syndrome

1 reference

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11 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

24 September 2018

Expression of Wiskott-Aldrich syndrome protein in dendritic cells regulates synapse formation and activation of naive CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

24 September 2018

Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells.

1 reference

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24 September 2018

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells

1 reference

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24 September 2018

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1 reference

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24 September 2018

Integrin-mediated long-term B cell retention in the splenic marginal zone.

1 reference

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24 September 2018

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

1 reference

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24 September 2018

Expansion and functional activity of Ly-1+ B cells upon transfer of peritoneal cells into allotype-congenic, newborn mice

1 reference

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14 November 2018

Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327460

14 November 2018

IL-12 deficiency in MRL-Fas(lpr) mice delays nephritis and intrarenal IFN-gamma expression, and diminishes systemic pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Wiskott-Aldrich syndrome: studies of lymphocytes, granulocytes, and platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity of a viral model vaccine after different inactivation procedures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immune response to pneumococcal polysaccharides: complement-mediated localization preferentially on CD21-positive splenic marginal zone B cells and follicular dendritic cells*

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wiskott-Aldrich syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marginal zone macrophages and immune responses against viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22302739

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2011-09-379412

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22302739%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22302739%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22302739%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

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