(Q41918415)

14 October 2017

title

Clotrimazole binds to heme and enhances heme-dependent hemolysis: proposed antimalarial mechanism of clotrimazole (English)

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14 October 2017

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1

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14 October 2017

Kaeko Kamei

2

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14 October 2017

Takushi Yamamoto

3

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14 October 2017

Yoshiro Kondo

4

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14 October 2017

Kenji Kanaori

5

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14 October 2017

Ryo Takano

6

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14 October 2017

Kunihiko Tajima

7

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14 October 2017

Saburo Hara

8

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14 October 2017

language of work or name

English

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publication date

13 November 2001

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Journal of Biological Chemistry

14 October 2017

published in

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14 October 2017

volume

277

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14 October 2017

issue

6

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14 October 2017

page(s)

4152-4158

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Induction and isolation of artemisinine-resistant mutants of Plasmodium falciparum.

14 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Clotrimazole inhibits the growth of Plasmodium falciparum in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Clotrimazole inhibits cell proliferation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Functional state of the plasma membrane Ca2+ pump in Plasmodium falciparum-infected human red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Depletion of intracellular Ca2+ stores, phosphorylation of eIF2alpha, and sustained inhibition of translation initiation mediate the anticancer effects of clotrimazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Role of glutathione in the detoxification of ferriprotoporphyrin IX in chloroquine resistant Plasmodium berghei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

The malaria parasite supplies glutathione to its host cell--investigation of glutathione transport and metabolism in human erythrocytes infected with Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Plasmodium falciparum-infected red blood cells depend on a functional glutathione de novo synthesis attributable to an enhanced loss of glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Chloroquine: mechanism of drug action and resistance in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Accumulation and drainage of hemin in the red cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

A spectroscopic study of the haemin--human-serum-albumin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Studies on haemin in dimethyl sulphoxide/water mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Thermodynamic factors controlling the interaction of quinoline antimalarial drugs with ferriprotoporphyrin IX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Hinding of imidazole and 2-methylimidazole by hemes in organic solvents. Evidence for five-coordination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Chloroquine-resistant Plasmodium falciparum: effect of substrate on chloroquine and amodiaquin accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Iron ligands in different forms of ferricytochrome c: The 620-nm band as a probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Alkaline haematin and nitrogenous ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

The effect of ferriprotoporphyrin IX and chloroquine on phospholipid monolayers and the possible implications to antimalarial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Interactions of hemin, antimalarial drugs and hemin-antimalarial complexes with phospholipid monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107285200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107285200

1 reference

14 October 2017

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